DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha6T and PUP3

DIOPT Version :9

Sequence 1:	NP_609623.1	Gene:	Prosalpha6T / 34726	FlyBaseID:	FBgn0032492	Length:	289	Species:	Drosophila melanogaster
Sequence 2:	NP_011020.3	Gene:	PUP3 / 856830	SGDID:	S000000896	Length:	205	Species:	Saccharomyces cerevisiae

Alignment Length:	223	Identity:	50/223 - (22%)
Similarity:	81/223 - (36%)	Gaps:	49/223 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 GAATVGLKGTDYAVLAALCRTSKDTNTLQRKIMPV--DDHVGMSIAGLTADARVVCQYMRTECMA 94
            |...|.:.|.|...:|...|....:..:..|...:  ..||.:.|.||..|...:.:..|.:...
Yeast     9 GGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLGITGLATDVTTLNEMFRYKTNL 73

  Fly    95 YRHSYNAEFPVRRLVSNLGNKLQTTTQ-----RYDRR--PYGVGLLVAGYDEQG--PHIYQVMPT 150
            |           :|......:.:|.||     .|:||  ||.||.:|||.:.:.  |.|    ..
Yeast    74 Y-----------KLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFI----AG 123

  Fly   151 ANVLNC-----KAMAIGSRSQS----ARTYLERNMESFEDCDMDELICHAIQAIRGSLGSDDVEN 206
            .:::.|     ..:..|:.|..    ..:..|.|:|..   |:.|.|.   ||:..:...|.:..
Yeast   124 FDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPE---DLFETIS---QALLNAADRDALSG 182

  Fly   207 LTINVAIVGKDVPFKMFTEAENQKYVKL 234
            ....|.|:.||...|        :|:|:
Yeast   183 WGAVVYIIKKDEVVK--------RYLKM 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha6T	NP_609623.1	PRE1	4..233	CDD:223711	49/220 (22%)
Prosalpha6T	NP_609623.1	proteasome_alpha_type_1	6..215	CDD:239718	45/202 (22%)
PUP3	NP_011020.3	proteasome_beta_type_3	8..201	CDD:239728	49/220 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810