DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha6T and PAF1

DIOPT Version :9

Sequence 1:	NP_609623.1	Gene:	Prosalpha6T / 34726	FlyBaseID:	FBgn0032492	Length:	289	Species:	Drosophila melanogaster
Sequence 2:	NP_199093.1	Gene:	PAF1 / 834290	AraportID:	AT5G42790	Length:	278	Species:	Arabidopsis thaliana

Alignment Length:	281	Identity:	128/281 - (45%)
Similarity:	174/281 - (61%)	Gaps:	7/281 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFRNQYDNDTTTWSPQGRLFQVEYAMEAVKQGAATVGLKGTDYAVLAALCRTSKDTNTLQRKIMP 65
            |||||||.|.|||||.||||||||||||||||:|.:||:...:.|||.:.:...:.::.||||..
plant     1 MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQRKIFK 65

  Fly    66 VDDHVGMSIAGLTADARVVCQYMRTECMAYRHSYNAEFPVRRLVSNLGNKLQTTTQRYDRRPYGV 130
            ||||:|::|||||||.||:.:|||:|.:.:..:|.:..||.|||.:|.:|.|..|||..:|||||
plant    66 VDDHIGVAIAGLTADGRVLSRYMRSESINHSFTYESPLPVGRLVVHLADKAQVCTQRSWKRPYGV 130

  Fly   131 GLLVAGYDEQGPHIYQVMPTANVLNCKAMAIGSRSQSARTYLERNMESFEDCDMDELICHAIQAI 195
            ||||.|.||.|.|:|...|:.|....:|.|||||||:|:|||||..|||.|...::||..||.|:
plant   131 GLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFGDSSREDLIKDAILAV 195

  Fly   196 RGSLGSDDVENLTINVAIVGKDVPFKMFTEAENQKYVKLVKAMDPPLEADHDPLSEEGMSDDDMT 260
            |.:|..:.:::....|||:|.|.||....:...||.:...:.:....|.:    .|.|..:.:..
plant   196 RETLQGETLKSSLCTVAILGVDEPFHFLDQEAIQKVIDTFEKVPEEEEGE----GEAGEGEAEAA 256

  Fly   261 DHGPSSSG---VPPNDTSDME 278
            :..|:..|   ....|.:.||
plant   257 EAAPAERGGGVAGDQDVAPME 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha6T	NP_609623.1	PRE1	4..233	CDD:223711	117/228 (51%)
Prosalpha6T	NP_609623.1	proteasome_alpha_type_1	6..215	CDD:239718	109/208 (52%)
PAF1	NP_199093.1	proteasome_alpha_type_1	6..215	CDD:239718	109/208 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	183	1.000	Domainoid score	I1012
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2080
Inparanoid	1	1.050	248	1.000	Inparanoid score	I1037
OMA	1	1.010	-	-		QHG53705
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	1	1.000	-	-		FOG0003679
OrthoInspector	1	1.000	-	-		mtm980
orthoMCL	1	0.900	-	-		OOG6_102143
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2552
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840