Protein Alignment Prosalpha6T and PSMB10

DIOPT Version :10

• Sequence 1: NP_609623.1
• Gene: Prosalpha6T / 34726
• FlyBaseID: FBgn0032492
• Length: 289
• Species: Drosophila melanogaster
• Sequence 2: NP_002792.1
• Gene: PSMB10 / 5699
• HGNCID: 9538
• Length: 273
• Species: Homo sapiens
• Alignment Length: 232
• Identity: 60/232 - (25%)
• Similarity: 91/232 - (39%)
• Gaps: 33/232 - (14%)

  Fly    28 AVKQGAATVGLKGTDYAVLAALCRTSKDTNTLQR---KIMPVDDHVGMSIAGLTADARVVCQYMR 89
            |.|.|....||...|..:|.|..|.:.|:....:   ||..:...:....||:.|||.     |.
Human    35 ARKTGTTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAE-----MT 94

  Fly    90 TECMAYRHSYNAEFPVRR-LVSNLGNKLQTTTQRYDRRPYGVGLLVAGYDEQGPHIYQVMPTANV 153
            |..:|.:...:|....|. .|:.:...|:.|..||... .|..|:|.|.|..||.:|.|.|..:.
Human    95 TRMVASKMELHALSTGREPRVATVTRILRQTLFRYQGH-VGASLIVGGVDLTGPQLYGVHPHGSY 158

  Fly   154 LNCKAMAIGSRSQSARTYLERNMESFEDCDMDE-LICHAIQA-IRGSLGSDDVENLTINVAIVGK 216
            ......|:||...:|...||...:.....:..: |:..|:.| |.|.|||..    .::..::.|
Human   159 SRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGG----NVDACVITK 219

  Fly   217 DVPFKMFTEAENQKYVKLVKAMDPPLEADHDPLSEEG 253
                   |.|      ||::.:..|.|    |:...|
Human   220 -------TGA------KLLRTLSSPTE----PVKRSG 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha6T	NP_609623.1	proteasome_alpha_type_1	6..215	CDD:239718	51/192 (27%)
PSMB10	NP_002792.1	proteasome_beta_type_7	40..227	CDD:239732	53/209 (25%)
		Pr_beta_C	231..267	CDD:463597	4/13 (31%)