DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha6T and psma1

DIOPT Version :9

Sequence 1:	NP_609623.1	Gene:	Prosalpha6T / 34726	FlyBaseID:	FBgn0032492	Length:	289	Species:	Drosophila melanogaster
Sequence 2:	NP_001008159.1	Gene:	psma1 / 493521	XenbaseID:	XB-GENE-995831	Length:	261	Species:	Xenopus tropicalis

Alignment Length:	259	Identity:	133/259 - (51%)
Similarity:	185/259 - (71%)	Gaps:	10/259 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFRNQYDNDTTTWSPQGRLFQVEYAMEAVKQGAATVGLKGTDYAVLAALCRTSKDTNTLQRKIMP 65
            |||||||||.|.||||||:.|:||||||||||:||||||....|||.||.|...:....|:||:.
Frog     1 MFRNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKSQAVLVALKRAQSELAAHQKKILN 65

  Fly    66 VDDHVGMSIAGLTADARVVCQYMRTECMAYRHSYNAEFPVRRLVSNLGNKLQTTTQRYDRRPYGV 130
            ||:|||:||||||||||::|.:||.||:..|..::...||.||||.:|:|.|..||||.||||||
Frog    66 VDNHVGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSQIGSKTQIPTQRYGRRPYGV 130

  Fly   131 GLLVAGYDEQGPHIYQVMPTANVLNCKAMAIGSRSQSARTYLERNMESFEDCDMDELICHAIQAI 195
            |||:||||:.||||:|..|:||..:|:||:||:|||||||||||:|..|.||::::|:.|.::|:
Frog   131 GLLIAGYDDMGPHIFQTSPSANYFDCRAMSIGARSQSARTYLERHMSEFLDCNLNDLVKHGLRAL 195

  Fly   196 RGSLGSD-DVENLTINVAIVGKDVPFKMFTEAENQKYV---------KLVKAMDPPLEADHDPL 249
            |.:|.:: |:....:::.||||::.|.::.:.|...::         |:....:.|:|...:|:
Frog   196 RETLPAEQDLTTKNVSIGIVGKEMEFTIYDDDEVAPFLEGLEERPQRKVAPPAEEPVEKQEEPM 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha6T	NP_609623.1	PRE1	4..233	CDD:223711	126/238 (53%)
Prosalpha6T	NP_609623.1	proteasome_alpha_type_1	6..215	CDD:239718	119/209 (57%)
psma1	NP_001008159.1	proteasome_alpha_type_1	6..216	CDD:239718	119/209 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	218	1.000	Domainoid score	I2606
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	289	1.000	Inparanoid score	I2754
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003679
OrthoInspector	1	1.000	-	-		otm48890
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2552
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.050