DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha6T and Psma1

DIOPT Version :9

Sequence 1:	NP_609623.1	Gene:	Prosalpha6T / 34726	FlyBaseID:	FBgn0032492	Length:	289	Species:	Drosophila melanogaster
Sequence 2:	NP_058974.1	Gene:	Psma1 / 29668	RGDID:	61841	Length:	263	Species:	Rattus norvegicus

Alignment Length:	261	Identity:	135/261 - (51%)
Similarity:	184/261 - (70%)	Gaps:	12/261 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFRNQYDNDTTTWSPQGRLFQVEYAMEAVKQGAATVGLKGTDYAVLAALCRTSKDTNTLQRKIMP 65
            |||||||||.|.||||||:.|:||||||||||:||||||...:|||.||.|...:....|:||:.
  Rat     1 MFRNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQKKILH 65

  Fly    66 VDDHVGMSIAGLTADARVVCQYMRTECMAYRHSYNAEFPVRRLVSNLGNKLQTTTQRYDRRPYGV 130
            ||:|:|:||||||||||::|.:||.||:..|..::...||.||||.:|:|.|..||||.||||||
  Rat    66 VDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGV 130

  Fly   131 GLLVAGYDEQGPHIYQVMPTANVLNCKAMAIGSRSQSARTYLERNMESFEDCDMDELICHAIQAI 195
            |||:||||:.|||::|..|:||..:|:||:||:|||||||||||:|..|..|::|||:.|.::|:
  Rat   131 GLLIAGYDDMGPHVFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMQCNLDELVKHGLRAL 195

  Fly   196 RGSLGSD-DVENLTINVAIVGKDVPFKMF-----------TEAENQKYVKLVKAMDPPLEADHDP 248
            |.:|.:: |:....:::.|||||:.|.::           .|...|:..:..:|.|.|.|...:|
  Rat   196 RETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLDGLEERPQRKAQPSQAADEPAEKADEP 260

  Fly   249 L 249
            :
  Rat   261 M 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha6T	NP_609623.1	PRE1	4..233	CDD:223711	127/240 (53%)
Prosalpha6T	NP_609623.1	proteasome_alpha_type_1	6..215	CDD:239718	118/209 (56%)
Psma1	NP_058974.1	proteasome_alpha_type_1	6..216	CDD:239718	118/209 (56%)
Psma1	NP_058974.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	232..263		7/30 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338838
Domainoid	1	1.000	217	1.000	Domainoid score	I2597
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2080
Inparanoid	1	1.050	290	1.000	Inparanoid score	I2712
OMA	1	1.010	-	-		QHG53705
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	1	1.000	-	-		FOG0003679
OrthoInspector	1	1.000	-	-		otm45795
orthoMCL	1	0.900	-	-		OOG6_102143
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2552
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770