DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha6T and pas-6

DIOPT Version :9

Sequence 1:	NP_609623.1	Gene:	Prosalpha6T / 34726	FlyBaseID:	FBgn0032492	Length:	289	Species:	Drosophila melanogaster
Sequence 2:	NP_504472.1	Gene:	pas-6 / 178943	WormBaseID:	WBGene00003927	Length:	260	Species:	Caenorhabditis elegans

Alignment Length:	230	Identity:	115/230 - (50%)
Similarity:	164/230 - (71%)	Gaps:	5/230 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFRNQYDNDTTTWSPQGRLFQVEYAMEAVKQGAATVGLKGTDYAVLAALCRTSKDTNTLQRKIMP 65
            |||||||.|.|.|||||||.|||||:||:|||:||||:|...:||:.||.|...|.::.|:|:..
Worm     1 MFRNQYDGDVTVWSPQGRLHQVEYAVEAMKQGSATVGIKSETHAVIVALKRAQNDLSSHQKKVYE 65

  Fly    66 VDDHVGMSIAGLTADARVVCQYMRTECMAYRHSYNAEFPVRRLVSNLGNKLQTTTQRYDRRPYGV 130
            :|.|.|:|||||.:|.|::.:|::|||.::|..|....|:::|..::..|||..||.|.|||:||
Worm    66 IDTHAGVSIAGLLSDGRILARYLQTECSSWRWDYKQAVPIKKLAESMQLKLQANTQYYGRRPFGV 130

  Fly   131 GLLVAGYDEQGPHIYQVMPTANVLNCKAMAIGSRSQSARTYLERNMESFEDCDMDELICHAIQAI 195
            |:|:||||:.|.||.|..|:|.|::....:||:||||||||||||:::||....::||.||:.|:
Worm   131 GILIAGYDKDGAHIIQTDPSAEVVSMHGTSIGARSQSARTYLERNVDNFEKSTPEQLIVHALLAL 195

  Fly   196 RGSLGSDDVENL---TINVAIVGKDVPFKMFTEAE 227
            |.:|.::  |||   ..::.|||||.||.:..:|:
Worm   196 RDTLPAE--ENLNAQNTSIGIVGKDSPFSLLEDAQ 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha6T	NP_609623.1	PRE1	4..233	CDD:223711	112/227 (49%)
Prosalpha6T	NP_609623.1	proteasome_alpha_type_1	6..215	CDD:239718	103/211 (49%)
pas-6	NP_504472.1	PRE1	4..237	CDD:223711	112/227 (49%)
pas-6	NP_504472.1	proteasome_alpha_type_1	6..216	CDD:239718	103/211 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158520
Domainoid	1	1.000	178	1.000	Domainoid score	I2120
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2080
Inparanoid	1	1.050	246	1.000	Inparanoid score	I2041
Isobase	1	0.950	-	0	Normalized mean entropy	S372
OMA	1	1.010	-	-		QHG53705
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	1	1.000	-	-		FOG0003679
OrthoInspector	1	1.000	-	-		otm14740
orthoMCL	1	0.900	-	-		OOG6_102143
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1003
SonicParanoid	1	1.000	-	-		X2552
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790