Protein Alignment KIF24 and kif2c

DIOPT Version :9

• Sequence 1: XP_011516163.1
• Gene: KIF24 / 347240
• HGNCID: 19916
• Length: 1399
• Species: Homo sapiens
• Sequence 2: XP_005163529.1
• Gene: kif2c / 100136875
• ZFINID: ZDB-GENE-070912-298
• Length: 700
• Species: Danio rerio
• Alignment Length: 598
• Identity: 228/598 - (38%)
• Similarity: 316/598 - (52%)
• Gaps: 107/598 - (17%)

Human    78 DMNDRKRL-FQLIKIIK-IMQEEDKAVSIP------ERHLQTSSLRIKSQEL------------- 121
            |||:...| ..||:.:: ..|||.....||      .:.::.|.|.::|..:
Zfish    54 DMNELNHLNSDLIQHLQPCHQEEPAPTPIPTPMTRMTKSVKASELPLRSSRIPTTSEPAPRDCPS 118

Human   122 ------RSGPRRQLNFDSPADNKDRNASNDGFEMCSLSD-FSANEQKSTYLKVLEHMLPDDSQYH 179
                  |...|:...|..||.....:||       |..| .|.|...||        :|..|.|.
Zfish   119 EEPASRRMTTRQTCLFRQPAPPPVVSAS-------SADDVLSQNLPSST--------IPKHSGYQ 168

Human   180 TKTGILNATAGDSYVQTE-ISTSLFSPNYLSAILGDCDIPIIQRISHVSGYNYGIPH--SCIRQN 241
            .:  :|:..|......|| |..|..|.   .|.:|    |...|:|.||..|.....  |..:..
Zfish   169 RR--LLSKPASPLLPSTEAICESEASK---CAPMG----PPSHRMSQVSETNKVANKRLSIAKMP 224

Human   242 TSEKQNPWTE------------------------------MEKIRVCVRKRPLGMREVRRGEINI 276
            .::|:..:.|                              ..:|.||||||||..:|:.:.||::
Zfish   225 DAQKRGKFGETNRSKQFYQMIEEYRETVQKVPMSLSDPVKTHRICVCVRKRPLNKKELAKKEIDV 289

Human   277 ITVEDKETLLVHEKKEAVDLTQYILQHVFYFDEVFGEACTNQDVYMKTTHPLIQHIFNGGNATCF 341
            :|:.....||:||.|:.||||:|:....|:||..|.|..||..||..|..||::.||.||.||||
Zfish   290 VTIPGNGVLLLHEPKQKVDLTKYLENQTFHFDYSFDEDATNDLVYRFTAKPLVKTIFEGGMATCF 354

Human   342 AYGQTGAGKTYTMIG------THENPGLYALAAKDIFRQLEVSQPR---KHLFVWISFYEIYCGQ 397
            ||||||:|||:||.|      .:.:.|:|||||:|:|..|.  |.|   ..|..:::|:|||.|:
Zfish   355 AYGQTGSGKTHTMGGDFSGKSQNSSKGIYALAAQDVFTLLR--QKRYVDMDLCPYVTFFEIYNGK 417

Human   398 LYDLLNRRKRLFAREDSKHMVQIVGLQELQVDSVELLLEVILKGSKERSTGATGVNADSSRSHAV 462
            ::||||::.:|...||.|..|.:|||||:.|..|:.::::|.:||..|::|.|..||.||||||:
Zfish   418 VFDLLNKKTKLRVLEDEKQQVNVVGLQEVPVSCVDDVIKMIERGSACRTSGQTFANASSSRSHAI 482

Human   463 IQIQIKDSAKRTF--GRISFIDLAGSERAADARDSDRQTKMEGAEINQSLLALKECIRALDQEHT 525
            :|:.::   :|.|  |:.|.:||||:||..|...:||.|.:|.||||:||||||||||:|.|...
Zfish   483 LQVILR---RRNFLYGKFSLVDLAGNERGTDVSSNDRHTIVETAEINRSLLALKECIRSLGQNSE 544

Human   526 HTPFRQSKLTQVLKDSFIG-NAKTCMIANISPSHVATEHTLNTLRYADRVKELKKGIKCCTSVTS 589
            |.|||.|||||||:||||| |::|||||.|||...:.|:||||||||:||||| .||....:|.:
Zfish   545 HIPFRMSKLTQVLRDSFIGENSRTCMIAMISPGMSSCEYTLNTLRYANRVKEL-NGISKGDAVEN 608

Human   590 RNR----TSGNSS 598
            .::    ..||||
Zfish   609 GSKLELSEEGNSS 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KIF24	XP_011516163.1	SAM_KIF24-like	34..93	CDD:188940	6/15 (40%)
		KISc_KIF2_like	254..575	CDD:276818	169/332 (51%)
		Kinesin	260..576	CDD:278646	166/327 (51%)
kif2c	XP_005163529.1	KISc_KIF2_like	267..595	CDD:276818	169/332 (51%)
		Kinesin	273..596	CDD:278646	166/327 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D202066at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100492
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820