DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16812 and RGD1307554

DIOPT Version :9

Sequence 1:	NP_609619.1	Gene:	CG16812 / 34722	FlyBaseID:	FBgn0032488	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_001103134.1	Gene:	RGD1307554 / 292739	RGDID:	1307554	Length:	413	Species:	Rattus norvegicus

Alignment Length:	465	Identity:	117/465 - (25%)
Similarity:	174/465 - (37%)	Gaps:	160/465 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SAARWVKFFNAAGIPSPAAAGYAHVFVENRIQDDMLLDLNKEYLREMGITLMGDIIAILRHSKTV 69
            :.:.|::||..||||...|..||.:||:||||..||||||||.:.|:|:|::|||||||:|:|.|
  Rat    33 ATSEWIQFFKEAGIPPGPAVNYAVMFVDNRIQKSMLLDLNKEIMNELGVTVVGDIIAILKHAKVV 97

  Fly    70 -----CEQNAREQVLTTEVVQSVVR--------------------PVSPKPKAPVATPKAKVYPP 109
                 |:........|...:|..:|                    |.:|..::..:|.|..|...
  Rat    98 HRQDMCKAATASVPCTPSPLQGELRRGASSAASRMIANSLNHDSPPHTPARRSDNSTSKISVTVS 162

  Fly   110 AKPA-----------------------RRVLPEHEGKYKVTLPSGTTERSKQILAKREKLYSDRV 151
            .|.|                       |||..|.||||.:.:|.|||.|:::||.:::     ..
  Rat   163 NKVAVKNAKAAALAHREEESLVVPTKRRRVTAEMEGKYIIHMPKGTTPRTRKILEQQQ-----AA 222

  Fly   152 SSSKKSDIFTRLHAEDEAQEGIVSSSGESSVRVHVAGASKTAATSSNNSVFARLGGKQGALPE-- 214
            ....::.:|.||.||.:|.                     |...:....||:||    ||.||
  Rat   223 KGLHRTSVFDRLGAETKAD---------------------TTTGTKPTGVFSRL----GATPEMD 262

  Fly   215 -----------EFTSTREIKSILKNTHRTVGGGGGGGGVTKNSP----IVKAKKVAAVTQQKVML 264
                       ..:|..:...:||..         |.|.||.||    .||||..::.|
  Rat   263 EELAWDSDNDSSSSSVLQYAGVLKKL---------GRGPTKASPQPALTVKAKATSSAT------ 312

  Fly   265 VHKVPLKKGDDDDDSMDDFESDEEDYMSSGEDFDMGAGEKIVKFASTAEVREI-VPESAYKNRQG 328
                                                      ..|||.::|.: :|......::.
  Rat   313 ------------------------------------------TLASTPKLRRLALPSRPGPEKKP 335

  Fly   329 KSFAN-NIKSRLG---MVSKLHATKKTYNLKASPARKPQARLSPVKGKTIRMRSDELFSRQD--- 386
            :|... :|..|||   :||:...::.|.....|......|....:.|......|:.|.::.|
  Rat   336 ESLPKVSILKRLGKAAVVSEAQDSQVTSTKSKSSTEVKFAIKRTLVGPRGSSSSESLGAQMDHAG 400

  Fly   387 TVPVHRRLGK 396
            ||.|.:|||:
  Rat   401 TVSVFKRLGR 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16812	NP_609619.1	SAM_CS047	6..70	CDD:188930	37/68 (54%)
CG16812	NP_609619.1	SAM	<26..72	CDD:197735	30/50 (60%)
RGD1307554	NP_001103134.1	SAM_CS047	34..98	CDD:188930	36/63 (57%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	135..156		3/20 (15%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	289..316		11/74 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340638
Domainoid	1	1.000	84	1.000	Domainoid score	I8123
eggNOG	1	0.900	-	-		E1_KOG3930
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1034351at2759
OrthoFinder	1	1.000	-	-		FOG0007515
OrthoInspector	1	1.000	-	-		oto96655
orthoMCL	1	0.900	-	-		OOG6_109403
Panther	1	1.100	-	-	LDO	PTHR21359
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6403
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.710