DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRF1 and Mtrfr

DIOPT Version :9

Sequence 1:	NP_609617.1	Gene:	mRF1 / 34720	FlyBaseID:	FBgn0032486	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001128189.1	Gene:	Mtrfr / 72650	MGIID:	1919900	Length:	184	Species:	Mus musculus

Alignment Length:	155	Identity:	37/155 - (23%)
Similarity:	68/155 - (43%)	Gaps:	26/155 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   203 RVQRVPATEKSGRMHTSTASI-------TVIPRPADIQVHIAEKDLKIETKRASGAGGQHVNTTD 260
            |:|..||....| |..||..:       .::|        :.|.:|:.:..:..|.|||..|.|.
Mouse    27 RLQEKPALLFPG-MAASTVQVAGRKDYPALLP--------LNESELEEQFVKGHGPGGQATNKTS 82

  Fly   261 SAVRIVHLPTGLAVEAQSERSQLKNRELAMKRLRSRL----------VQQQLESVEASKMATKKA 315
            :.|.:.|:|:|:.|:....||..:||::|.|.|:.::          |.::....|..|...||.
Mouse    83 NCVVLKHVPSGIVVKCHQTRSVDQNRKIARKVLQEKVDVFYNGENSPVHKEKLEAERRKRERKKR 147

  Fly   316 QQGSLNRNEKIRTYNFVQDRITDHR 340
            .:.:|.:.:.::........||:.:
Mouse   148 AKETLEKKKLLKELREASQNITEKK 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRF1	NP_609617.1	prfA	35..378	CDD:234801	37/155 (24%)
		PCRF	58..222	CDD:281461	8/18 (44%)
		RF-1	234..338	CDD:278876	27/113 (24%)
Mtrfr	NP_001128189.1	RF-1	58..>119	CDD:278876	20/60 (33%)
		GGQ domain. /evidence=ECO:0000269\|PubMed:22821833	60..124		20/63 (32%)
		GGQ. /evidence=ECO:0000269\|PubMed:22821833	74..76		1/1 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	132..184		7/41 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810