DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9426 and AFR

DIOPT Version :9

Sequence 1:	NP_609616.1	Gene:	CG9426 / 34719	FlyBaseID:	FBgn0032485	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_565572.1	Gene:	AFR / 816990	AraportID:	AT2G24540	Length:	372	Species:	Arabidopsis thaliana

Alignment Length:	352	Identity:	80/352 - (22%)
Similarity:	135/352 - (38%)	Gaps:	89/352 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   281 VKVIDKALKDDCRDMSVKIALRSICRDIASKRGQLVPLRVCPRQLAKKNIYIIGGSHRDTPRTWN 345
            :..|:...:::.|..|..: :..:..|||    :|..||: |        |.....:|....:||
plant    10 INTINDQAEEETRTKSQPL-ISGLPNDIA----ELCLLRL-P--------YPYHALYRSVSSSWN 60

  Fly   346 -----------------SADCIFETVAKFDIFRREWTETAPMEVGR--ILPGV----------SA 381
                             |:..:|.........|.:| ::..:..||  :||.:          .|
plant    61 KTITNPRFLFSKQSLSISSPYLFVFAFNKSTARIQW-QSLDLASGRWFVLPPMPNSFTKISSPHA 124

  Fly   382 LN-------GKIYVVGGERGSQILANGEVYDPQNDVWQPIAPMIVPRCEFGLCTMGGNLFAVGGW 439
            |:       ||::|:|   |..:..:..||....:.|..|:||:.||..|....:.|.:.||||
plant   125 LSCASMPRQGKLFVLG---GGDVNRSAVVYTALTNRWSCISPMMSPRTYFVSGNVNGKIMAVGG- 185

  Fly   440 IGDDIGGS------MECYDPEQDLWKLMGSMPQPRFSMGVVSFEGLIYIVGGCTTTTRHLPDLIS 498
               .:||:      :|.|||:.|.|.::..:|     |.:..::..:.....|.|.....|  ..
plant   186 ---SVGGNGEATTEVESYDPDNDTWTVVKKLP-----MVLAKYDSAVIGKEMCVTEGWAWP--FM 240

  Fly   499 FNPVTK-------EWNELA-RMQTARCQMGVAVLDRYLYVVGGSSISQDILSSVERYSFDEDKWT 555
            |.|:.:       .|.|:: .|:.....:.|.:.|| |:|:   |...|....|  |..|:|.|.
plant   241 FPPMGQVYDSDEGTWREMSGGMKEGWTGVSVVIRDR-LFVI---SEHGDFPMKV--YCSDDDTWR 299

  Fly   556 TVCALNVP----RAIPAVVAADGLLYV 578
            .|....:.    |...||..||..::|
plant   300 YVSGEKLQGEKMRRPFAVTGADDRVFV 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9426	NP_609616.1	BTB	73..179	CDD:279045
		PHA03098	78..558	CDD:222983	73/326 (22%)
		BACK	187..289	CDD:285009	1/7 (14%)
		Kelch	330..384	CDD:128874	14/89 (16%)
		KELCH repeat	374..417	CDD:276965	14/61 (23%)
		Kelch	385..431	CDD:128874	13/45 (29%)
		KELCH repeat	421..465	CDD:276965	15/49 (31%)
		Kelch	<447..478	CDD:128874	8/36 (22%)
		Kelch_6	467..516	CDD:290672	9/56 (16%)
		KELCH repeat	468..512	CDD:276965	8/51 (16%)
		Kelch_1	515..557	CDD:279660	12/41 (29%)
		KELCH repeat	516..561	CDD:276965	13/44 (30%)
		KELCH repeat	564..617	CDD:276965	6/15 (40%)
		Kelch	575..627	CDD:128874	1/4 (25%)
AFR	NP_565572.1	F-box	27..72	CDD:279040	11/58 (19%)
		Kelch_1	167..214	CDD:279660	16/50 (32%)
		KELCH repeat	168..214	CDD:276965	15/49 (31%)
		KELCH repeat	217..259	CDD:276965	7/43 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	57	1.000	Inparanoid score	I2576
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.050