Protein Alignment CG9426 and Klhl13

DIOPT Version :10

• Sequence 1: NP_609616.1
• Gene: CG9426 / 34719
• FlyBaseID: FBgn0032485
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: NP_001368820.1
• Gene: Klhl13 / 67455
• MGIID: 1914705
• Length: 660
• Species: Mus musculus
• Alignment Length: 622
• Identity: 166/622 - (26%)
• Similarity: 279/622 - (44%)
• Gaps: 91/622 - (14%)

  Fly    44 LGSGATAASHRTNLPS-----YCNAQYPFKVLSNLNQLREQSRFCDVEIIAGMA--TLSAHRAVL 101
            |||....:||..:..:     :.:..:...||...:|||.....|||.::.|..  ....||.::
Mouse    53 LGSEMGLSSHLQSCKAGSTRIFTSNSHSSVVLQGFDQLRLDGLLCDVTLMPGDTDDAYPVHRVMM 117

  Fly   102 SAASAYFEAMFRPELGLNEVKQKSVVLHTIDGDILHILLDFIYTGRCEITQSNVQELLAAADMLQ 166
            ::||.||:|||..  |:.|.:...:.||.:....|..::|||||.:..:....:|:.|.||..||
Mouse   118 ASASDYFKAMFTG--GMKEQELMCIKLHGVSRVGLRKIIDFIYTAKLSLNMDTLQDTLEAASFLQ 180

  Fly   167 LNEVVDGCCEFLCRELHASNALGILRFAEAHNCESLAKSALNFVHANFPAVTLEDEFLETPQTLL 231
            :..|:|.|..||...:...|.:.:.|.|..::...:.|...:||..||.|:....|||:.|...|
Mouse   181 ILPVLDFCKVFLISGVTLDNCVEVGRIANTYHLTEVDKYVNSFVLKNFAALLSTGEFLKLPFERL 245

  Fly   232 SQLLNSELLRVDSESQVFQAALRWI-----KHDVTQRRCYVFDVLSHVRMALVP-------VKVI 284
            :.:|:|..|:..:|..:|:|..||:     :.||..:      ::.::|..|:.       |:.:
Mouse   246 AFVLSSNSLKRCTELDLFKATCRWLRLEEPRMDVAAK------LMKNIRFPLMTPQELINYVQTV 304

  Fly   285 DKALKDD-CRDMSVKIA-----------LRSICRDIASKRGQLVPL-RVCPRQLAKKNIYIIGGS 336
            |....|: |.::.::.:           ::|....|.|...:||.| .|..:||.
Mouse   305 DFMRTDNTCVNLLLEASNYQMMPFMQPVMQSDRTAIRSDTTRLVTLGGVLRQQLV---------- 359

  Fly   337 HRDTPRTWNSADCIFETVAKFDIFRREWTETAPMEVGRILPGVSALNGKIYVVGGE-----RGSQ 396
                         :.:.:..:|....||...|||:..|...|::.:...:|||||:     :|..
Mouse   360 -------------VSKELRMYDEKTHEWKSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKT 411

  Fly   397 ILANGEVYDPQNDVWQPIAPMIVPRCEFGLCTMGGNLFAVGGWIGDDIGGSMECYDPEQDLWKLM 461
            .:.....:||:.:.|..:|.:...|..|.|..:.|.|:||||........::|||:|..:.|..:
Mouse   412 AVDTVFRFDPRYNKWIQVASLNEKRTFFHLSALKGFLYAVGGRNAAGELPTVECYNPRTNEWTYV 476

  Fly   462 GSMPQPRFSMGVVSFEGLIYIVGGCTTTTRHLPDLISFNPVTKEWNELARMQTAR-----CQMGV 521
            ..|.:|.:......:.|::||.||.|..| ...:|:.|:|.|.:|.:.|.|.|.|     |.:|
Mouse   477 AKMNEPHYGHAGTVYGGVMYISGGITHDT-FQKELMCFDPDTDKWTQKAPMTTVRGLHCMCTVG- 539

  Fly   522 AVLDRYLYVVG-----GSSISQDILSSVERYSFDEDKWTTVCALNVPRAIPAVVAADGLLYVAGG 581
               || |||:|     |:|...|:| |.|.||...|:||.:.::...::...|...:..:||.||
Mouse   540 ---DR-LYVIGGNHFRGTSDYDDVL-SCEYYSPILDQWTPIASMLRGQSDVGVAVFENKIYVVGG 599

  Fly   582 DQPCEVNFYRAQVTINAVECYDPLSDTWKNCPDLPVS 618
            ..      :..:..:..|:.|||..:.|....|||.|
Mouse   600 YS------WNNRCMVEIVQKYDPEKNEWHKVFDLPES 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9426	NP_609616.1	BTB_POZ_KLHL27_IPP	63..189	CDD:349565	40/127 (31%)
		PHA03098	78..558	CDD:222983	142/521 (27%)
		KELCH repeat	374..417	CDD:276965	12/47 (26%)
		KELCH repeat	421..465	CDD:276965	14/43 (33%)
		KELCH repeat	468..512	CDD:276965	13/43 (30%)
		KELCH repeat	516..561	CDD:276965	20/54 (37%)
		KELCH repeat	564..617	CDD:276965	12/52 (23%)
		Kelch	575..627	CDD:128874	13/44 (30%)
Klhl13	NP_001368820.1	BTB_POZ_KLHL9_13	74..201	CDD:349548	39/128 (30%)
		PHA03098	97..640	CDD:222983	156/578 (27%)
		KELCH repeat	384..432	CDD:276965	12/47 (26%)
		KELCH repeat	436..480	CDD:276965	14/43 (33%)
		KELCH repeat	483..528	CDD:276965	14/45 (31%)
		KELCH repeat	530..579	CDD:276965	20/54 (37%)
		KELCH repeat	582..629	CDD:276965	12/52 (23%)