DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9426 and Gmcl1

DIOPT Version :9

Sequence 1:	NP_609616.1	Gene:	CG9426 / 34719	FlyBaseID:	FBgn0032485	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_001029103.1	Gene:	Gmcl1 / 312516	RGDID:	1359265	Length:	524	Species:	Rattus norvegicus

Alignment Length:	177	Identity:	46/177 - (25%)
Similarity:	77/177 - (43%)	Gaps:	6/177 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 DVEIIAGMATLSAHRAVLSAASAYFEAMFR---PELGLNEVKQKSVVLHTIDGDILHILLDFIYT 145
            |::|.|.....|.|:..| ..|.||.:||.   .|..:| :.:..:....||.:.|.:....:|.
  Rat   107 DIKICALGEEWSLHKIYL-CQSGYFSSMFSGSWKESSMN-IIELEIPDQNIDIEALQVAFGSLYR 169

  Fly   146 GRCEITQSNVQELLAAADMLQLNEVVDGCCEFLCRELHASNALGILRFAEAHNCESLAKSALNFV 210
            ....|..|.|..:||||.||||:.::..|.|.:...:......|....|..:..:|:.|..|.::
  Rat   170 DDVLIKPSRVVAILAAACMLQLDGLIQQCGETMKETISVRTVCGYYTSAGTYGLDSVKKKCLEWL 234

  Fly   211 HANFPAVTLEDEFLETPQTLLSQLL-NSELLRVDSESQVFQAALRWI 256
            ..|.......:.|.|....::.||: :|.|..:..|..|:.|..:|:
  Rat   235 LNNLMTHQSVELFKELSINVMRQLIGSSNLFVMQVEMDVYTALKKWM 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9426	NP_609616.1	BTB	73..179	CDD:279045	30/97 (31%)
		PHA03098	78..558	CDD:222983	46/177 (26%)
		BACK	187..289	CDD:285009	16/71 (23%)
		Kelch	330..384	CDD:128874
		KELCH repeat	374..417	CDD:276965
		Kelch	385..431	CDD:128874
		KELCH repeat	421..465	CDD:276965
		Kelch	<447..478	CDD:128874
		Kelch_6	467..516	CDD:290672
		KELCH repeat	468..512	CDD:276965
		Kelch_1	515..557	CDD:279660
		KELCH repeat	516..561	CDD:276965
		KELCH repeat	564..617	CDD:276965
		Kelch	575..627	CDD:128874
Gmcl1	NP_001029103.1	BTB_POZ_GCL	91..205	CDD:349614	30/99 (30%)
Gmcl1	NP_001029103.1	BACK_GCL	206..283	CDD:350570	16/76 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910