Protein Alignment CG9426 and Klhl17

DIOPT Version :10

• Sequence 1: NP_609616.1
• Gene: CG9426 / 34719
• FlyBaseID: FBgn0032485
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: XP_006239583.1
• Gene: Klhl17 / 246757
• RGDID: 708444
• Length: 650
• Species: Rattus norvegicus
• Alignment Length: 575
• Identity: 188/575 - (32%)
• Similarity: 286/575 - (49%)
• Gaps: 44/575 - (7%)

  Fly    73 LNQLREQSRFCDVEIIAGMATLSAHRAVLSAASAYFEAMFRPELGLNEVKQKSVVLHTIDGDILH 137
            ::::|::...||:.:......:.||:.||::.|.||.|||..|  ::|.:|..|.||.||...|.
  Rat    80 MSRMRQRGLLCDIVLHVAAKEIRAHKVVLASCSPYFHAMFTNE--MSESRQTHVTLHDIDPQALD 142

  Fly   138 ILLDFIYTGRCEITQSNVQELLAAADMLQLNEVVDGCCEFLCRELHASNALGILRFAEAHNCESL 202
            .|:.|.||....:.:.|||.||.||.:||||.|.|.||:||..:|..||.|||..||:.|:|..|
  Rat   143 QLVQFAYTAEIVVGEGNVQTLLPAASLLQLNGVRDACCKFLLSQLDPSNCLGIRGFADTHSCSDL 207

  Fly   203 AKSALNFVHANFPAVTLEDEFLETPQTLLSQLLNSELLRVDSESQVFQAALRWIKHDVTQRRCYV 267
            .|:|..:|..:|..|...:||:..|...:.:|::|:.|.|.||..|::|.|.|:||||..||.:|
  Rat   208 LKAAHRYVLQHFVDVAKTEEFMLLPLKQVLELVSSDSLNVPSEEDVYRAVLSWVKHDVDTRRQHV 272

  Fly   268 FDVLSHVRMALVPVKVI------DKALK--DDCRDMSVKIALRSICRDIASKRGQLVPLRVCPRQ 324
            ..::..||:.|:....:      :..::  .||:|:.:: ||:  ...:..:||.|...|..||:
  Rat   273 PRLMKCVRLPLLSRDFLLGHVDAESLVRHHPDCKDLLIE-ALK--FHLLPEQRGVLGTSRTRPRR 334

  Fly   325 L--AKKNIYIIGGSHRDTPRTWNSADCIFETVAKFDIFRREWTETAPMEVGRILPGVSALNGKIY 387
            .  |...::.:||         .|...|......:|.....|...|.|...|...||:|:..::|
  Rat   335 CEGAGPVLFAVGG---------GSLFAIHGDCEAYDTRTDRWHVVASMSTRRARVGVAAVGNRLY 390

  Fly   388 VVGGERGSQILANGEVYDPQNDVWQPIAPMIVPRCEFGLCTMGGNLFAVGGWIGDDIGGSMECYD 452
            .|||..|:..||..|.|||..:.|||...|...|...|:..:.|.|:|.||:.|.....|.|.||
  Rat   391 AVGGYDGTSDLATVESYDPVTNTWQPEVSMGTRRSCLGVAALHGLLYAAGGYDGASCLNSAERYD 455

  Fly   453 PEQDLWKLMGSMPQPRFSMGVVSF----------EGLIYIVGGCTTTTRHLPDLISFNPVTKEWN 507
            |....|..:.:|...|..:.|.:.          :|.:|.|||..::: ||..:..:.|....|.
  Rat   456 PLTGTWTSIAAMSTRRRYVRVATLGASWVYCLPTDGNLYAVGGYDSSS-HLATVEKYEPQVNSWT 519

  Fly   508 ELARMQTARCQMGVAVLDRYLYVVGGSSISQDILSSVERYSFDEDKWTTVCALNVPRAIPAVVAA 572
            .:|.|.:.|...|||||:..|||.||:. ....|:||||||.....|.:|..:|:.|:...:||.
  Rat   520 PVASMLSRRSSAGVAVLEGALYVAGGND-GTSCLNSVERYSTKAGAWESVAPMNIRRSTHDLVAM 583

  Fly   573 DGLLYVAGGDQPCEVNFYRAQVTINAVECYDPLSDTWKNCPDLPVSRSEAGAVVV 627
            ||.||..||:.        ...::|::|.|:|.::.|.....:...||..|..|:
  Rat   584 DGWLYAVGGND--------GSSSLNSIEKYNPRTNKWVAASCMFTRRSSVGVAVL 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9426	NP_609616.1	BTB_POZ_KLHL27_IPP	63..189	CDD:349565	46/115 (40%)
		PHA03098	78..558	CDD:222983	167/499 (33%)
		KELCH repeat	374..417	CDD:276965	18/42 (43%)
		KELCH repeat	421..465	CDD:276965	14/43 (33%)
		KELCH repeat	468..512	CDD:276965	12/53 (23%)
		KELCH repeat	516..561	CDD:276965	20/44 (45%)
		KELCH repeat	564..617	CDD:276965	14/52 (27%)
		Kelch	575..627	CDD:128874	12/51 (24%)
Klhl17	XP_006239583.1	BTB_POZ_KLHL17_actinfilin	51..189	CDD:349555	44/110 (40%)
		PHA03098	90..566	CDD:222983	166/491 (34%)
		BACK	187..288	CDD:475122	39/100 (39%)
		KELCH repeat	377..420	CDD:276965	18/42 (43%)
		KELCH repeat	424..468	CDD:276965	14/43 (33%)
		KELCH repeat	471..526	CDD:276965	13/55 (24%)
		KELCH repeat	528..572	CDD:276965	20/44 (45%)
		KELCH repeat	575..620	CDD:276965	14/52 (27%)
		Kelch	587..631	CDD:128874	13/52 (25%)