DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG9426 and Gmcl1

DIOPT Version :9

Sequence 1:NP_609616.1 Gene:CG9426 / 34719 FlyBaseID:FBgn0032485 Length:627 Species:Drosophila melanogaster
Sequence 2:NP_035948.3 Gene:Gmcl1 / 23885 MGIID:1345156 Length:524 Species:Mus musculus


Alignment Length:358 Identity:74/358 - (20%)
Similarity:124/358 - (34%) Gaps:109/358 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    84 DVEIIAGMATLSAHRAVLSAASAYFEAMFR---PELGLNEVKQKSVVLHTIDGDILHILLDFIYT 145
            |::|.|.....|.|:..| ..|.||.:||.   .|..:| :.:..:....||.:.|.:....:|.
Mouse   107 DIKICALGEEWSLHKIYL-CQSGYFSSMFSGSWKESSMN-IIELEIPDQNIDIEALQVAFGSLYR 169

  Fly   146 GRCEITQSNVQELLAAADMLQLNEVVDGCCEFLCRELHASNALGILRFAEAHNCESLAKSALNFV 210
            ....|..|.|..:||||.||||:.::..|.|.:...:......|....|..:..:|:.|..|.::
Mouse   170 DDVLIKPSRVVAILAAACMLQLDGLIQQCGETMKETISVRTVCGYYTSAGTYGLDSVKKKCLEWL 234

  Fly   211 HANFPAVTLEDEFLETPQTLLSQLL-NSELLRVDSESQVFQAALRW------------IKHDVTQ 262
            ..|.......:.|.|....::.||: :|.|..:..|..|:.|..:|            :|..:|:
Mouse   235 LNNLMTHQSVELFKELSINVMKQLIGSSNLFVMQVEMDVYTALKKWMFLQLVPSWNGSLKQLLTE 299

  Fly   263 RRCYV------FD---------------VLSHVRMALVPVKVIDKALKDDCRDMSVKIALRSICR 306
            ...:.      |:               |..|:|                         |:.|..
Mouse   300 TDVWFSKWKKDFEGTTFLETEQGKPFAPVFRHLR-------------------------LQYIIS 339

  Fly   307 DIASKRGQLVPLRVCPRQLAKKNIYIIGGSHRDT--PRTWNSADCIFETVAKFDIFRREW----- 364
            |:||.|                   ||   .:|:  |..|.:|           :::::|     
Mouse   340 DLASAR-------------------II---EQDSLVPSEWLAA-----------VYKQQWLAMLR 371

  Fly   365 ----TETAPMEVGR-ILPGVSALNGKIYVVGGE 392
                :|..|.|:.: .|.|.|...|:.....||
Mouse   372 AEQDSEVGPQEINKEELEGNSMRCGRKLAKDGE 404

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9426NP_609616.1 BTB 73..179 CDD:279045 30/97 (31%)
PHA03098 78..558 CDD:222983 74/358 (21%)
BACK 187..289 CDD:285009 22/135 (16%)
Kelch 330..384 CDD:128874 13/65 (20%)
KELCH repeat 374..417 CDD:276965 6/20 (30%)
Kelch 385..431 CDD:128874 2/8 (25%)
KELCH repeat 421..465 CDD:276965
Kelch <447..478 CDD:128874
Kelch_6 467..516 CDD:290672
KELCH repeat 468..512 CDD:276965
Kelch_1 515..557 CDD:279660
KELCH repeat 516..561 CDD:276965
KELCH repeat 564..617 CDD:276965
Kelch 575..627 CDD:128874
Gmcl1NP_035948.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..37
Nuclear localization signal. /evidence=ECO:0000255 47..53
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 63..83
Nuclear localization signal. /evidence=ECO:0000255 83..89
BTB 96..203 CDD:279045 30/97 (31%)
BTB 107..206 CDD:197585 30/100 (30%)
BACK 211..>281 CDD:197943 15/69 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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