Protein Alignment CG9426 and Klhl36

DIOPT Version :10

• Sequence 1: NP_609616.1
• Gene: CG9426 / 34719
• FlyBaseID: FBgn0032485
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: NP_666331.1
• Gene: Klhl36 / 234796
• MGIID: 2385305
• Length: 613
• Species: Mus musculus
• Alignment Length: 600
• Identity: 163/600 - (27%)
• Similarity: 260/600 - (43%)
• Gaps: 82/600 - (13%)

  Fly    69 VLSNLNQLREQSRFCDVEIIAGMATLSAHRAVLSAASAYFEAMFRPELGLNEVKQKSVVLHTIDG 133
            ||..||:.|....||||.::.....:.|||.:|:..|.||.:||  .||:.|..||.|.|.....
Mouse    31 VLQRLNEQRLHGLFCDVVLVVEEQQVPAHRNLLAVCSDYFNSMF--TLGMREAFQKEVELVGTSY 93

  Fly   134 DILHILLDFIYTGRCEITQSNVQELLAAADMLQLNEVVDGCCEFLCRELHASNALGILRFAEAHN 198
            ..|..::||:|:...|:..||:..:|..|.:||:..|||.|||:|.:|:...|.|.:...|..::
Mouse    94 VGLKAVVDFLYSSELELDGSNIDYILETAHLLQIWTVVDFCCEYLEQEVSEDNYLYLQELASIYS 158

  Fly   199 CESLAKSALNFVHANFPAVTLEDEFLETPQT-LLSQLLNSELLRVDSESQVFQAALRWIKHDVTQ 262
            .:.|.....:||.::|..::...:||::... .|...|:|..::...|..:.|.||:|:... .:
Mouse   159 LKRLDAFIDSFVLSHFSTLSFTPDFLQSISVQKLCVYLSSGQVQHKWEYDLLQVALQWLTQQ-PE 222

  Fly   263 RRCYVFDVLSHVRMALVPVKVIDKALKDDCRDMSVKIALRSICRDIASKRG----------QLV- 316
            |..:...||.::|..|.|         :|.....||:|:.|:....|:..|          .||
Mouse   223 REVHTRRVLENIRFPLFP---------EDILLQRVKLAMCSLLPSEANGEGFVEEAMHYHNSLVA 278

  Fly   317 -PLRVCPRQLAKKN--IYIIGGSHRDTPRTWNSADCIFETVAKFDIFRREWTETAPMEVGRILPG 378
             |:....|.|.:..  :..:||...:.....:...|..:|.      ..:|.:...:...|....
Mouse   279 QPVLQTKRTLLRSEECLLFVGGEVSERCLELSDDTCYLDTK------NEQWVKETSLPARRSHHC 337

  Fly   379 VSALNGKIYVVGG----ERGSQILANGEV-YDPQNDVWQPIAPMIVPRCEFGLCTMGGNLFAVGG 438
            |:.|.|.|::.||    :.|....:|... |||:...|..:|.|...|.:|.|.::...|.||||
Mouse   338 VAVLGGFIFIAGGSFSRDNGGNAASNLLYRYDPRRKQWIKVASMNQRRVDFYLASIEDMLVAVGG 402

  Fly   439 WIGDDIGGSMECYDPEQDLWKLMGSMPQPRFSMGVVS--FEGLIYIVGGCTTTTRH-------LP 494
            ...:....|:|.|.|:.:.|..:..:  |||:.|...  ::..:||.||      |       ..
Mouse   403 RNENGALSSVETYSPKTNSWTYVAGL--PRFTYGHAGTIYKDFVYISGG------HDYQIGPYRK 459

  Fly   495 DLISFNPVTKEWNELARMQTAR-----CQMGVAVLDRYLYVVGGSSISQDILSSVER-------- 546
            :|:.::..|..|.|...|.|||     |.:|.::     |.:||   |.|.:.|:||
Mouse   460 NLLCYDHRTDVWEERRPMTTARGWHSMCSLGDSI-----YSIGG---SDDHMESMERFDVLGVEA 516

  Fly   547 YSFDEDKWTTVCALNVPRAIPAVVAADGLLYVAGGDQPCEVNFYRAQVTINAVECYDPLSDTWKN 611
            ||...::||.|..|....:...|....|.:|:.||.......|.|      ||:.||..::.|..
Mouse   517 YSPQCNQWTRVAPLLQANSESGVAVWQGRIYILGGYSWESTAFSR------AVQVYDSEANRWSR 575

  Fly   612 CPDLPVSRSEAGAVV 626
            .||||.:.:...|.|
Mouse   576 GPDLPNAIAGVSACV 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9426	NP_609616.1	BTB_POZ_KLHL27_IPP	63..189	CDD:349565	45/119 (38%)
		PHA03098	78..558	CDD:222983	138/521 (26%)
		KELCH repeat	374..417	CDD:276965	14/47 (30%)
		KELCH repeat	421..465	CDD:276965	13/43 (30%)
		KELCH repeat	468..512	CDD:276965	12/52 (23%)
		KELCH repeat	516..561	CDD:276965	16/57 (28%)
		KELCH repeat	564..617	CDD:276965	15/52 (29%)
		Kelch	575..627	CDD:128874	15/51 (29%)
Klhl36	NP_666331.1	BTB_POZ	20..154	CDD:453885	46/124 (37%)
		BACK	142..240	CDD:475122	22/98 (22%)
		Kelch 1	294..343		8/54 (15%)
		NanM	322..590	CDD:442289	79/289 (27%)
		KELCH repeat	333..381	CDD:276965	14/47 (30%)
		Kelch 2	344..395		14/50 (28%)
		KELCH repeat	385..429	CDD:276965	13/45 (29%)
		Kelch 3	396..442		14/47 (30%)
		KELCH repeat	432..479	CDD:276965	11/52 (21%)
		Kelch 4	444..491		14/52 (27%)
		KELCH repeat	481..531	CDD:276965	16/57 (28%)
		Kelch 5	492..544		15/59 (25%)
		KELCH repeat	534..580	CDD:276965	14/51 (27%)
		Kelch 6	545..593		15/51 (29%)