Protein Alignment CG9426 and Klhl41

DIOPT Version :10

• Sequence 1: NP_609616.1
• Gene: CG9426 / 34719
• FlyBaseID: FBgn0032485
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: NP_001074556.1
• Gene: Klhl41 / 228003
• MGIID: 2683854
• Length: 606
• Species: Mus musculus
• Alignment Length: 585
• Identity: 159/585 - (27%)
• Similarity: 258/585 - (44%)
• Gaps: 84/585 - (14%)

  Fly    73 LNQLREQSRFCDVEIIAGMATLSAHRAVLSAASAYFEAMFRPELGLNEVKQKSVVLHTIDGDILH 137
            |..|.|:.:|.|..:.||..:...||.:|||.|.||...|..|  :.|.|:|.|.|..:|..||.
Mouse    23 LKDLLEEKKFIDCTLKAGDKSFPCHRLILSACSPYFREYFLSE--IEEEKKKEVALDNVDPAILD 85

  Fly   138 ILLDFIYTGRCEITQSNVQELLAAADMLQLNEVVDGCCEFLCRELHASNALGILRFAEAHNCESL 202
            :::.::|:...::...|||::.|.:...|:..|...|..:|.:.|...|.|.|||.....:|..|
Mouse    86 LIIKYLYSASIDLNDGNVQDIFALSSRFQIPSVFTVCVSYLQKRLAPGNCLAILRLGLLLDCPRL 150

  Fly   203 AKSALNFVHANFPAVTLEDEFLE-TPQTLLSQLLNSELLRVDSESQVFQAALRWIKHDVTQRRCY 266
            |.||..||...|..:..|::|:: :||.|:| :::::.|.|:.|..||:|.::|::.|...|...
Mouse   151 AISAREFVSDRFVQICKEEDFMQLSPQELIS-VISNDSLNVEKEEVVFEAVMKWVRTDKENRAKN 214

  Fly   267 VFDVLSHVRMALVPVKVI-DKALKDDCRDMSVKIALR-SICRDI-----------ASKRG----- 313
            :.:|...:|..|:..|.. |...|||....:.::..: .:.:|.           |.|.|
Mouse   215 LSEVFDCIRFRLMAEKYFKDHVEKDDIIKSNPEVQKKIKVLKDAFAGKLPEPSKNAEKAGAGEVN 279

  Fly   314 ------QLVP--LRVCPR--QLAKKNIYIIGGSHRDTPRTWNSADCIFETVAKFDIFRREWTETA 368
                  .|:|  |...||  ...|..|.::    .||            ....:|....|...||
Mouse   280 GDVGDEDLLPGYLNDIPRHGMFVKDLILLV----NDT------------AAVAYDPMENECYLTA 328

  Fly   369 PME-VGRILPGVSALNGKIYVVGG-----ERGSQILANGEVY----DPQNDVWQPIAPMIVPRCE 423
            ..| :.|....:.....::|||||     |...|.|   :.|    |.....|..:.|:...||.
Mouse   329 LAEQIPRNHSSLVTQQNQVYVVGGLYVDEENKDQPL---QSYFFQLDNVTSEWVGLPPLPSARCL 390

  Fly   424 FGLCTMGGNLFAVGGWIGDDIG-----GSMECYDPEQDLWKLMGSMPQPRFSMGVVSFEGLIYIV 483
            |||..:...::.|.   |.|:.     .|:.||||....|..:.::|...:...|:|..|:||.:
Mouse   391 FGLGEVDDKIYVVA---GKDLQTEASLDSVLCYDPVAAKWSEVKNLPIKVYGHNVISHNGMIYCL 452

  Fly   484 GGCTTTTRHLPDLISFNPVTKEWNELARMQTARCQMGVAVLDRYLYVVGGSSISQDILS-SVERY 547
            ||.|...:....:..:||...:|.:||.|:|.|...|||:....:.:.||  :::|.|| |||.:
Mouse   453 GGKTDDKKCTNRVFIYNPKKGDWKDLAPMKTPRSMFGVAIHKGKIVIAGG--VTEDGLSASVEAF 515

  Fly   548 SFDEDKWTTVCALNVPRAIPAVVAADGLLYVAGGDQPCEVNFYRAQVTINAVECYDP--LSDTWK 610
            ....:||..:......|:..::|:..|.||..||         .|.:.:.:.| :.|  ::|.||
Mouse   516 DLKTNKWEVMTEFPQERSSISLVSLAGALYAIGG---------FAMIQLESKE-FAPTEVNDIWK 570

  Fly   611  610
            Mouse   571  570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9426	NP_609616.1	BTB_POZ_KLHL27_IPP	63..189	CDD:349565	36/115 (31%)
		PHA03098	78..558	CDD:222983	144/524 (27%)
		KELCH repeat	374..417	CDD:276965	12/51 (24%)
		KELCH repeat	421..465	CDD:276965	14/48 (29%)
		KELCH repeat	468..512	CDD:276965	13/43 (30%)
		KELCH repeat	516..561	CDD:276965	14/45 (31%)
		KELCH repeat	564..617	CDD:276965	13/49 (27%)
		Kelch	575..627	CDD:128874	10/38 (26%)
Klhl41	NP_001074556.1	BTB_POZ_KLHL41_KBTBD10	6..135	CDD:349650	35/113 (31%)
		PHA03098	39..578	CDD:222983	154/569 (27%)
		KELCH repeat	335..384	CDD:276965	12/51 (24%)
		Kelch 1	346..398		17/54 (31%)
		KELCH repeat	388..433	CDD:276965	14/47 (30%)
		Kelch 2	399..447		12/50 (24%)
		KELCH repeat	437..482	CDD:276965	13/44 (30%)
		Kelch 3	448..495		16/46 (35%)
		KELCH repeat	485..530	CDD:276965	14/46 (30%)
		Kelch 4	497..542		12/46 (26%)
		Kelch 5	544..599		10/37 (27%)