Protein Alignment CG9426 and Klhl29

DIOPT Version :10

• Sequence 1: NP_609616.1
• Gene: CG9426 / 34719
• FlyBaseID: FBgn0032485
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: NP_001157965.1
• Gene: Klhl29 / 208439
• MGIID: 2683857
• Length: 875
• Species: Mus musculus
• Alignment Length: 632
• Identity: 160/632 - (25%)
• Similarity: 263/632 - (41%)
• Gaps: 76/632 - (12%)

  Fly    27 NQNPTGGGGDGDFFGQNLGSGATAASHRTNLPSYCNAQYPFKVLSNLNQLREQSRFCDVEIIAGM 91
            |..||.....|....:.:|.|..         .:.:..:|.::|..|||.|....|.|::|:...
Mouse   282 NGPPTTDSAHGLQMLRTIGVGKY---------EFTDPGHPKEMLKELNQQRRAKAFTDLKIVVEG 337

  Fly    92 ATLSAHRAVLSAASAYFEAMFRPELGLNEVKQKS-----VVLHTIDGDILHILLDFIYTGRCEIT 151
            .....|:.||::.|.||:.:.  :..:.:..|.|     :||..:..|:|.:||:|:|||...|.
Mouse   338 REFEVHQNVLASCSLYFKDLI--QRSVQDSSQSSREKLELVLSNLQADVLELLLEFVYTGSLVID 400

  Fly   152 QSNVQELLAAADMLQLNEVVDGCCEFLCRELHASNALGILRFAEAHNCESLAKSALNFVHANFPA 216
            .:|.:.||.||...|.:.....|..||.::|.|||.||:|..|||..|..|...|..|....||.
Mouse   401 SANAKTLLEAASKFQFHTFCKVCVSFLEKQLTASNCLGVLAMAEAMQCSELYHMAKAFALQIFPE 465

  Fly   217 VTLEDEFLETPQTLLSQLLNSELLRVDSESQVFQAALRWIKHDVTQRRCYVFDVLSHVRMALV-P 280
            |..::|.|...:......::::.|...:|..|::..::|||.|...|..|..::|:.||:..: |
Mouse   466 VAAQEEILSISKDDFIAYVSNDSLNTKAEELVYETVIKWIKKDPATRAQYAAELLAAVRLPFIHP 530

  Fly   281 VKVIDKALKDDCRDMSVKIALRSICRDIA--SKRGQLVP--------LRVCPRQLA--KKNIYII 333
            ..:::..      |....|.....|||:.  :||..::|        .|..||..|  .:.|.::
Mouse   531 SYLLNVV------DNEELIKSSEACRDLVNEAKRYHMLPHARQEMQTPRTRPRLSAGVAEVIVLV 589

  Fly   334 GGSHR--DTPRT------WNSADCIFETVAKFDIFRREWTETAPMEVGRILPGVSALNGKIYVVG 390
            ||...  .|.|:      ||..:..:..:|....:.||:...           ||| ...||:.|
Mouse   590 GGRQMVGMTQRSLVAVTCWNPQNNKWYPLASLPFYDREFFSV-----------VSA-GDNIYLSG 642

  Fly   391 GERGSQILANGEVYDPQNDVWQPIAPMIVPRCEFGLCTMGGNLFAVGGWIGDDIGGS---MECYD 452
            |......||:...|....|.|..::.|.||||........|.::.:|| :|  :.|:   :|.||
Mouse   643 GMESGVTLADVWCYMSLLDNWNLVSRMTVPRCRHNSLVYDGKIYTLGG-LG--VAGNVDHVERYD 704

  Fly   453 PEQDLWKLMGSMPQPRFSMGVVSFEGLIYIVGGCTTTTRHLPDLISFNPVTKEWNELARMQTARC 517
            ...:.|:.:..:|:...|.......|.||:.||.....|....|.|:.|.|..|:.:........
Mouse   705 TITNQWEAVAPLPKAVHSAAATVCGGKIYVFGGVNEAGRAAGVLQSYVPQTNTWSFIESPMIDNK 769

  Fly   518 QMGVAVLDRYLYVVGGSSISQDILSSVERYSFDEDKWTTVCA--LNVPRAIPAVVAADGLLYVAG 580
            ......|:.:::::||:......:       :|.:|......  :|..|...:.|..||.:|..|
Mouse   770 YAPAVTLNGFVFILGGAYARATTI-------YDPEKGNIKAGPNMNHSRQFCSAVVLDGKIYATG 827

  Fly   581 GDQPCEVNFYRAQVTINAVECYDPLSDTWKNCPDLPVSRSEAGAVVV 627
            |....|      ...:..:|.|:|.::||...|.:|......|.||:
Mouse   828 GIVSSE------GPALGNMEAYEPTTNTWTLLPHMPCPVFRHGCVVI 868

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9426	NP_609616.1	BTB_POZ_KLHL27_IPP	63..189	CDD:349565	41/130 (32%)
		PHA03098	78..558	CDD:222983	129/508 (25%)
		KELCH repeat	374..417	CDD:276965	12/42 (29%)
		KELCH repeat	421..465	CDD:276965	11/46 (24%)
		KELCH repeat	468..512	CDD:276965	12/43 (28%)
		KELCH repeat	516..561	CDD:276965	5/46 (11%)
		KELCH repeat	564..617	CDD:276965	14/52 (27%)
		Kelch	575..627	CDD:128874	13/51 (25%)
Klhl29	NP_001157965.1	PHA03247	<39..290	CDD:223021	3/7 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	113..145
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..291		3/8 (38%)
		BTB_POZ	312..438	CDD:453885	41/127 (32%)
		PHA03098	333..860	CDD:222983	143/562 (25%)
		BACK_KLHL29_KBTBD9	432..533	CDD:350543	31/100 (31%)
		KELCH repeat	577..621	CDD:276965	10/43 (23%)
		Kelch 1	585..635		13/61 (21%)
		KELCH repeat	626..669	CDD:276965	14/54 (26%)
		Kelch 2	637..683		14/45 (31%)
		KELCH repeat	673..716	CDD:276965	11/45 (24%)
		Kelch 3	684..730		10/48 (21%)
		KELCH repeat	720..808	CDD:276965	17/94 (18%)
		Kelch 4	732..778		11/45 (24%)
		Kelch 5	779..821		7/48 (15%)
		KELCH repeat	811..857	CDD:276965	14/51 (27%)
		Kelch 6	822..870		14/53 (26%)