Protein Alignment CG9426 and Keap1

DIOPT Version :10

• Sequence 1: NP_609616.1
• Gene: CG9426 / 34719
• FlyBaseID: FBgn0032485
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: XP_061507293.1
• Gene: Keap1 / 1274312
• VectorBaseID: AGAMI1_007316
• Length: 1057
• Species: Anopheles gambiae
• Alignment Length: 618
• Identity: 199/618 - (32%)
• Similarity: 293/618 - (47%)
• Gaps: 60/618 - (9%)

  Fly    28 QNPTGGGGDGDFFGQNLGSGATAASHRTNL--PSYCNAQYPFKVLSNLNQLREQSRFCDVEIIAG 90
            |:..||||.|       |..:.||:.|.:|  .::....|..:||..:..:|......||.:...
Mosquito   117 QSGGGGGGGG-------GGASNAATAREDLGDMAFYMPNYSREVLKMMFMMRSHHMLTDVTLEVE 174

  Fly    91 MATLSAHRAVLSAASAYFEAMFRPELGLNEVKQKSVVLHTIDGDILHILLDFIYTGRCEITQSNV 155
            ..|..||:.||||||.||:|||..  ||.|.:...|.|..:....:..:|.|:|||:..:|:..|
Mosquito   175 QETFHAHKVVLSAASPYFKAMFTG--GLKECEMARVKLQGVCPTAMTRILFFMYTGQIRVTELTV 237

  Fly   156 QELLAAADMLQLNEVVDGCCEFLCRELHASNALGILRFAEAHNCESLAKSALNFVHANFPAVTLE 220
            .:||.||.|.|:..|:|.||:||.|:|..:||:||..|||.|.||||.:.|..|:..||..:..|
Mosquito   238 CQLLPAATMFQVPNVIDACCDFLERQLDPTNAIGIANFAEQHGCESLRQKANQFIERNFTQICRE 302

  Fly   221 DEFLETPQTLLSQLLNSELLRVDSESQVFQAALRWIKHDVTQRRCYVFDVLSHVRMALVPVKVID 285
            :|||:.....|..|:..:.|.|..|..|:.|.|:|:|:|...|...:..:||.||..|:....:.
Mosquito   303 EEFLQLSVMQLICLIRKDELNVQGERDVYDAVLKWVKYDEDNRYPKMESILSAVRCQLLTPSFLK 367

  Fly   286 KALKD--------DCRDMSVKIALRSICRDIASKRGQLVPLRVCPRQLAKKNIYIIGGSHRDTPR 342
            :.:|:        .||:.     |..|..|:...:...|..|   :....:.|::.||.::.:
Mosquito   368 EQMKNCAVLRRAPGCREY-----LAKIFHDLTLHKRPAVRER---KPNTTRMIFVAGGYYKHS-- 422

  Fly   343 TWNSADCIFETVAKFDIFRREWTETAPMEVGRILPGVSALNGKIYVVGGERGSQILANGEVYD-- 405
                    .:.:..:::..:.|.....:.|.|...|.:.|.|..|.|||...|.    |..||
Mosquito   423 --------LDMLEGYNVDDKVWLTLPKLTVPRSGLGAAFLKGTFYAVGGRNNSP----GSSYDSD 475

  Fly   406 ------PQNDVWQPIAPMIVPRCEFGLCTMGGNLFAVGGWIGDDIGGSMECYDPEQDLWKLMGSM 464
                  |..:.|:|.:||.|||...|:..|...|:||||..|.|...::|.||||.|.|.|:..|
Mosquito   476 WVDRYNPVTERWRPCSPMSVPRNRVGVAVMDELLYAVGGSSGSDYHNTVEYYDPETDRWTLVQPM 540

  Fly   465 PQPRFSMGVVSFEGLIYIVGGCTTTTRHLPDLISFNPVTKEWNELARMQTARCQMGVAVLDRYLY 529
            ...|..:||.....|:|.:||....|| |..:..::|....|..:..|:..|...|||.|.:|:|
Mosquito   541 QSKRLGVGVAVVNRLLYAIGGFDGKTR-LASVECYHPENNAWTLVPPMRYGRSGAGVAALHQYIY 604

  Fly   530 VVGGSSISQDILSSVERYSFDEDKWTTVCALNVPRAIPAVVAADGLLYVAGGDQPCEVNFYRAQV 594
            ||||...::. |:|||||..::..|..|..:.:.|:..::...||.||..||        |..|.
Mosquito   605 VVGGFDGTRQ-LASVERYDTEQQCWEMVAPVRIARSALSLTVLDGRLYAIGG--------YDGQD 660

  Fly   595 TINAVECYDPLSDTWKNCPDLPVSRS-EAGAVV 626
            .:..||.|||:.|.|.....|...|| .|.||:
Mosquito   661 FLTIVEVYDPVRDVWDEGTPLTSGRSGHASAVI 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9426	NP_609616.1	BTB_POZ_KLHL27_IPP	63..189	CDD:349565	48/125 (38%)
		PHA03098	78..558	CDD:222983	161/495 (33%)
		KELCH repeat	374..417	CDD:276965	15/50 (30%)
		KELCH repeat	421..465	CDD:276965	18/43 (42%)
		KELCH repeat	468..512	CDD:276965	12/43 (28%)
		KELCH repeat	516..561	CDD:276965	19/44 (43%)
		KELCH repeat	564..617	CDD:276965	17/52 (33%)
		Kelch	575..627	CDD:128874	19/53 (36%)
Keap1	XP_061507293.1	None