| Sequence 1: | NP_609615.2 | Gene: | kek4 / 34718 | FlyBaseID: | FBgn0032484 | Length: | 649 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_115928.1 | Gene: | SLITRK2 / 84631 | HGNCID: | 13449 | Length: | 845 | Species: | Homo sapiens |
| Alignment Length: | 583 | Identity: | 122/583 - (20%) |
|---|---|---|---|
| Similarity: | 188/583 - (32%) | Gaps: | 211/583 - (36%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 29 LIFRSASADWLLDCGNCHCKWNSGKK--TADCRNLSLSGV----PEYLSP--------------- 72
Fly 73 ----EVQVLDLSH---NHIFYLEENAFLTTHLQNLQKLLIRNGTLKYLNQRSFTQLQILIELDLS 130
Fly 131 NNLLVDLLPNVFDCLSKVRAIFLNGNLLQALRHGVFRNLKYLHKIELKRNRLVSIDAKAFVGVPL 195
Fly 196 LSQIYLDNNELTKLRVESFQD-LTKLTALSLVENPWNCTCDLQMFRDFVIGMN--LYTPPTSCHY 257
Fly 258 P-------LQLRGRLWI------------------EDQPEAFACKPKIVYPTLSTSI-------- 289
Fly 290 -------------------------------NTSKENVTLICRVHGSPNTVIAWDYTNQVYESRS 323
Fly 324 KPVKSLQKQRIYIEL------------------LREDESKIRKFGHDVFVSRLTIVNAR-KSDEG 369
Fly 370 VYTCLAENPGGKDSVHISVVVQKDMERISLIDSNFFAIVCLIAMGFLSMSILFSLVTCLIFKRFK 434
Fly 435 QFHP--------------------------GQ----HTYLQ--PTSLPVQSPGSEEATAISAL 465 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| kek4 | NP_609615.2 | LRR | 59..>228 | CDD:443914 | 48/195 (25%) |
| leucine-rich repeat | 75..99 | CDD:275380 | 11/26 (42%) | ||
| LRR_8 | 98..158 | CDD:404697 | 19/59 (32%) | ||
| leucine-rich repeat | 100..123 | CDD:275380 | 6/22 (27%) | ||
| leucine-rich repeat | 124..147 | CDD:275380 | 8/22 (36%) | ||
| leucine-rich repeat | 148..171 | CDD:275380 | 8/22 (36%) | ||
| leucine-rich repeat | 172..195 | CDD:275380 | 1/22 (5%) | ||
| leucine-rich repeat | 196..219 | CDD:275380 | 8/23 (35%) | ||
| LRRCT | 228..277 | CDD:214507 | 17/75 (23%) | ||
| IG_like | 294..390 | CDD:214653 | 19/114 (17%) | ||
| Ig strand B | 296..300 | CDD:409353 | 1/3 (33%) | ||
| Ig strand C | 309..323 | CDD:409353 | 2/13 (15%) | ||
| Ig strand E | 356..360 | CDD:409353 | 1/3 (33%) | ||
| Ig strand F | 370..375 | CDD:409353 | 1/4 (25%) | ||
| Ig strand G | 383..386 | CDD:409353 | 0/2 (0%) | ||
| SLITRK2 | NP_115928.1 | LRR 1 | 63..84 | ||
| LRR | <66..>197 | CDD:443914 | |||
| leucine-rich repeat | 67..87 | CDD:275380 | |||
| LRR 2 | 87..108 | ||||
| leucine-rich repeat | 88..111 | CDD:275380 | |||
| LRR 3 | 111..132 | ||||
| leucine-rich repeat | 112..135 | CDD:275380 | |||
| LRR 4 | 135..156 | ||||
| leucine-rich repeat | 136..159 | CDD:275380 | |||
| LRR 5 | 159..180 | ||||
| leucine-rich repeat | 160..181 | CDD:275380 | |||
| Required for interaction with PTPRD. /evidence=ECO:0000250|UniProtKB:Q810C0 | 167..215 | ||||
| leucine-rich repeat | 208..369 | CDD:275380 | 6/40 (15%) | ||
| LRRCT | 216..>252 | CDD:214507 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 263..321 | ||||
| leucine-rich repeat | 370..400 | CDD:275380 | 4/29 (14%) | ||
| LRR 7 | 376..397 | 2/20 (10%) | |||
| LRR | <378..>529 | CDD:443914 | 45/177 (25%) | ||
| LRR_8 | 399..459 | CDD:404697 | 22/61 (36%) | ||
| LRR 8 | 400..421 | 9/22 (41%) | |||
| leucine-rich repeat | 401..424 | CDD:275380 | 11/24 (46%) | ||
| LRR 9 | 424..445 | 5/20 (25%) | |||
| leucine-rich repeat | 425..448 | CDD:275380 | 6/22 (27%) | ||
| LRR 10 | 448..469 | 6/20 (30%) | |||
| leucine-rich repeat | 449..468 | CDD:275380 | 5/18 (28%) | ||
| LRR 11 | 472..493 | 8/45 (18%) | |||
| leucine-rich repeat | 473..491 | CDD:275380 | 7/17 (41%) | ||
| LRR 12 | 495..516 | 6/20 (30%) | |||
| leucine-rich repeat | 496..509 | CDD:275378 | 4/12 (33%) | ||
| leucine-rich repeat | 521..533 | CDD:275378 | 5/11 (45%) | ||
| LRRCT | 529..579 | CDD:214507 | 15/49 (31%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||