| Sequence 1: | NP_609615.2 | Gene: | kek4 / 34718 | FlyBaseID: | FBgn0032484 | Length: | 649 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_076941.2 | Gene: | LRFN4 / 78999 | HGNCID: | 28456 | Length: | 635 | Species: | Homo sapiens |
| Alignment Length: | 397 | Identity: | 93/397 - (23%) |
|---|---|---|---|
| Similarity: | 145/397 - (36%) | Gaps: | 67/397 - (16%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 27 LALIFRSASADWLLDCGNCHCKWNSGKKTADCRNLSLSGVPEYLSPEVQVLDLSHNHIFYLEENA 91
Fly 92 FLTTHLQNLQKLLIRNGTLKYLNQRSFTQLQILIELDLSNNLLVDLLPNVFDCLSKVRAIFLNGN 156
Fly 157 LLQALRHGVFRN-LKYLHKIELKRNRLVSIDAKAFVGVPLLSQIYLDNNELTKLRVESFQDLTKL 220
Fly 221 TALSLVE-------------------------------NPWNCTCDLQMFRDFVIGMNLYTPPTS 254
Fly 255 CHYPLQLRGR-LWIEDQPEAFACKPKIVYPTLSTSINTSKENVTLICRVHGSPNTVIAWDYTNQV 318
Fly 319 YESRSKPVKSLQKQRIYIELLREDESKIRKFGHDVFVSRLTIVNARKSDEGVYTCLAENPGGKDS 383
Fly 384 VHISVVV 390 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| kek4 | NP_609615.2 | LRR | 59..>228 | CDD:443914 | 43/200 (22%) |
| leucine-rich repeat | 75..99 | CDD:275380 | 6/23 (26%) | ||
| LRR_8 | 98..158 | CDD:404697 | 15/59 (25%) | ||
| leucine-rich repeat | 100..123 | CDD:275380 | 5/22 (23%) | ||
| leucine-rich repeat | 124..147 | CDD:275380 | 7/22 (32%) | ||
| leucine-rich repeat | 148..171 | CDD:275380 | 7/23 (30%) | ||
| leucine-rich repeat | 172..195 | CDD:275380 | 4/22 (18%) | ||
| leucine-rich repeat | 196..219 | CDD:275380 | 7/22 (32%) | ||
| LRRCT | 228..277 | CDD:214507 | 16/49 (33%) | ||
| IG_like | 294..390 | CDD:214653 | 22/95 (23%) | ||
| Ig strand B | 296..300 | CDD:409353 | 2/3 (67%) | ||
| Ig strand C | 309..323 | CDD:409353 | 1/13 (8%) | ||
| Ig strand E | 356..360 | CDD:409353 | 1/3 (33%) | ||
| Ig strand F | 370..375 | CDD:409353 | 3/4 (75%) | ||
| Ig strand G | 383..386 | CDD:409353 | 0/2 (0%) | ||
| LRFN4 | NP_076941.2 | LRR 1 | 49..70 | 6/22 (27%) | |
| leucine-rich repeat | 50..73 | CDD:275380 | 6/24 (25%) | ||
| LRR | <52..>215 | CDD:443914 | 40/164 (24%) | ||
| LRR 2 | 73..94 | 4/20 (20%) | |||
| leucine-rich repeat | 74..97 | CDD:275380 | 5/22 (23%) | ||
| LRR 3 | 97..118 | 7/20 (35%) | |||
| leucine-rich repeat | 98..121 | CDD:275380 | 7/22 (32%) | ||
| LRR 4 | 121..142 | 6/20 (30%) | |||
| leucine-rich repeat | 122..146 | CDD:275380 | 7/23 (30%) | ||
| LRR 5 | 146..161 | 4/14 (29%) | |||
| leucine-rich repeat | 147..170 | CDD:275380 | 4/22 (18%) | ||
| LRR 6 | 170..191 | 6/20 (30%) | |||
| leucine-rich repeat | 171..194 | CDD:275380 | 7/22 (32%) | ||
| LRR 7 | 194..215 | 3/20 (15%) | |||
| leucine-rich repeat | 195..213 | CDD:275380 | 3/17 (18%) | ||
| LRRCT | 234..278 | CDD:214507 | 16/48 (33%) | ||
| Ig | 281..368 | CDD:472250 | 22/110 (20%) | ||
| Ig strand B | 298..302 | CDD:409421 | 2/3 (67%) | ||
| Ig strand C | 311..315 | CDD:409421 | 0/3 (0%) | ||
| Ig strand E | 334..338 | CDD:409421 | 1/3 (33%) | ||
| Ig strand F | 348..353 | CDD:409421 | 3/4 (75%) | ||
| Ig strand G | 361..364 | CDD:409421 | 0/2 (0%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 373..410 | ||||
| fn3 | 409..478 | CDD:394996 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 555..583 | ||||
| PDZ-binding | 632..635 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||