Protein Alignment kek4 and Lingo3

DIOPT Version :9

• Sequence 1: NP_001260435.1
• Gene: kek4 / 34718
• FlyBaseID: FBgn0032484
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001103079.1
• Gene: Lingo3 / 690755
• RGDID: 1592209
• Length: 589
• Species: Rattus norvegicus
• Alignment Length: 559
• Identity: 121/559 - (21%)
• Similarity: 185/559 - (33%)
• Gaps: 194/559 - (34%)

  Fly    47 CKWNSGKKTADCRNLSLSGVPEYLS------------------------PEVQVLDLSHNHIFYL 87
            |:.::..:|..|....|:.|||.:.                        |.::.|||:||.|.::
  Rat    28 CECSASTRTVACGRRRLTAVPEGIPAETRMLELSRNRIRCLNPGDLASLPTLEELDLNHNVIAHV 92

  Fly    88 EENAFLTTHLQNLQKLLIRNGTLKYLNQRSFTQLQILIELDLSNNLLVDLLPNVFDCLSKVR--- 149
            |..||  .:|..|:.|.:|...||.:....||.|..|..||||.|.||.||...|..|..::
  Rat    93 EPGAF--ANLPRLRVLRLRGNQLKLIPPGVFTHLDSLTLLDLSENKLVILLDFSFQDLRSLQRLE 155

  Fly   150 -----AIFLN----------------------------GNL--LQALR----------------- 162
                 .:|::                            |:|  |.|||
  Rat   156 VGDNDLVFISRRAFAGLLGLAELTLERCNLTSLSPESLGHLRGLGALRLRHLAIAALEDQNFQKL 220

  Fly   163 ----------------------------------------------------------------- 162
                                                                             
  Rat   221 PGLLHLEIDNWPLLEEVAPGSLRGLNLTSLSITHTNITAVPAAALRQQAHLTCLNLSHNPISMVP 285

  Fly   163 HGVFRNLKYLHKIELKRNRLVSIDAKAFVGVPLLSQIYLDNNELTKLRVESFQDLTKLTALSLVE 227
            .|.||:|..|.::.|....|..|:.:||||:..:..:.|.:|.|:.|...:|..:..|..|.:..
  Rat   286 RGSFRDLVRLRELHLAGALLAVIEPQAFVGLRQIRLLNLSDNLLSTLEENTFHSVNTLETLRVDG 350

  Fly   228 NPWNCTCDLQMFRDFVIGMNLYTPPTSCHYPLQLRGRLWIEDQP-----EAFAC-KPKIVYPTLS 286
            ||..|.|.|.........:|......:|..|.::||.. :.:.|     |.|.| ||||....|.
  Rat   351 NPLACDCRLLWIVQRRKTLNFDGRLPACATPAEVRGDA-LHNLPDSVLFEYFVCRKPKIRERRLQ 414

  Fly   287 TSINTSKENVTLICRVHGSPNTVIAWDYTNQVYESRSKPVKSLQKQRIYIELLREDESKIRKFGH 351
            ....|..::|..:||..|.|...:||                :..|...:.......:::...|
  Rat   415 HVTATEGDDVRFLCRAEGEPAPTVAW----------------VTPQHHSVTAASRGRARVLPGG- 462

  Fly   352 DVFVSRLTIVNARKSDEGVYTCLAENPGGKDSVHISVVV-------QKDMERISLIDSNF----F 405
                 .|.|.:.|..|.|.|||:|.|.||.|:...::.:       |.|....:.:...|    .
  Rat   463 -----TLAITDTRPQDSGTYTCVASNAGGNDTYFATLTIHPAANRTQSDGHNETQVGVRFPLDLT 522

  Fly   406 AIVCLIAMG---FLSMSILFSLVTCLIFKRFKQFHPGQH 441
            .|:...|||   ||.: :||..:...::.|.:    |||
  Rat   523 TILVSTAMGCITFLGV-VLFCFLLLFVWSRGR----GQH 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek4	NP_001260435.1	leucine-rich repeat	75..99	CDD:275380	10/23 (43%)
		LRR_8	99..158	CDD:290566	23/96 (24%)
		leucine-rich repeat	100..123	CDD:275380	8/22 (36%)
		leucine-rich repeat	124..147	CDD:275380	12/22 (55%)
		LRR_8	146..206	CDD:290566	21/179 (12%)
		leucine-rich repeat	148..171	CDD:275380	11/142 (8%)
		leucine-rich repeat	172..195	CDD:275380	8/22 (36%)
		leucine-rich repeat	196..219	CDD:275380	5/22 (23%)
		TPKR_C2	228..277	CDD:301599	14/54 (26%)
		IG_like	294..390	CDD:214653	22/95 (23%)
		Ig	296..387	CDD:143165	22/90 (24%)
Lingo3	NP_001103079.1	LRRNT	23..55	CDD:214470	7/26 (27%)
		leucine-rich repeat	34..53	CDD:275380	6/18 (33%)
		LRR	<55..353	CDD:227223	58/299 (19%)
		leucine-rich repeat	55..78	CDD:275380	0/22 (0%)
		leucine-rich repeat	79..102	CDD:275380	10/24 (42%)
		leucine-rich repeat	103..150	CDD:275380	20/46 (43%)
		leucine-rich repeat	151..174	CDD:275380	1/22 (5%)
		leucine-rich repeat	175..198	CDD:275380	2/22 (9%)
		leucine-rich repeat	199..222	CDD:275380	4/22 (18%)
		leucine-rich repeat	223..246	CDD:275380	0/22 (0%)
		LRR_8	246..302	CDD:404697	6/55 (11%)
		leucine-rich repeat	247..270	CDD:275380	0/22 (0%)
		leucine-rich repeat	271..292	CDD:275380	3/20 (15%)
		leucine-rich repeat	295..316	CDD:275380	7/20 (35%)
		leucine-rich repeat	319..342	CDD:275380	5/22 (23%)
		PCC	331..>405	CDD:188093	18/74 (24%)
		Ig	407..489	CDD:416386	25/103 (24%)
		Ig strand A'	413..417	CDD:409353	1/3 (33%)
		Ig strand B	423..432	CDD:409353	3/8 (38%)
		Ig strand C	437..442	CDD:409353	2/20 (10%)
		Ig strand C'	445..447	CDD:409353	0/1 (0%)
		Ig strand D	456..459	CDD:409353	0/2 (0%)
		Ig strand E	462..469	CDD:409353	3/12 (25%)
		Ig strand F	475..483	CDD:409353	5/7 (71%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46071
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000