DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek4 and Tril

DIOPT Version :9

Sequence 1:NP_001260435.1 Gene:kek4 / 34718 FlyBaseID:FBgn0032484 Length:649 Species:Drosophila melanogaster
Sequence 2:NP_080093.1 Gene:Tril / 66873 MGIID:1914123 Length:809 Species:Mus musculus


Alignment Length:269 Identity:78/269 - (28%)
Similarity:111/269 - (41%) Gaps:37/269 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    38 WLLDCG--------------NCHCKWNSGKKTADCRNLSLSGVPEYLS-PEVQ-VLDLSHNHIFY 86
            ||:.||              .|.|:   ..:...|.|..|..||:..| |..| ||..|....|.
Mouse    10 WLVVCGCLAFPPRAESVCPERCDCQ---HPQHLLCTNRGLRAVPKTSSLPSPQDVLTYSLGGNFI 71

  Fly    87 LEENAFLTTHLQNLQKLLIRNGTLKYLNQRSFTQLQILIELDLSNNLLVDLLPNVFDCLSKVRAI 151
            ....||....|..|::|.::...::.|:.::|.:|..|.||.|.||||..|:|.....|.|:|.:
Mouse    72 TNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALVPGTLAPLRKLRIL 136

  Fly   152 FLNGNLLQALRHGVFRNLKYLHKIELKRNRLVSIDAKAFVGVPLLSQIYLDNNELTKLRVESFQD 216
            :.|||.:..|..|.|..|:.|.|:.|..|.|.::....|..:..|..::|::|.:..|...:|..
Mouse   137 YANGNEIGRLSRGSFEGLESLVKLRLDGNVLGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFSQ 201

  Fly   217 LTKLTALSLVENPWNCTCDLQMFRDFVIGMNLYT------------PPTSCHYP----LQLRGRL 265
            |.||..|:|..|  .....|:....||...:|.|            |....|.|    |.|.|..
Mouse   202 LGKLRFLNLSAN--ELQPSLRHAATFVPLRSLSTLILSANSLQHLGPRVFQHLPRLGLLSLSGNQ 264

  Fly   266 WIEDQPEAF 274
            .....||||
Mouse   265 LTHLAPEAF 273

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek4NP_001260435.1 leucine-rich repeat 75..99 CDD:275380 8/24 (33%)
LRR_8 99..158 CDD:290566 21/58 (36%)
leucine-rich repeat 100..123 CDD:275380 5/22 (23%)
leucine-rich repeat 124..147 CDD:275380 11/22 (50%)
LRR_8 146..206 CDD:290566 18/59 (31%)
leucine-rich repeat 148..171 CDD:275380 8/22 (36%)
leucine-rich repeat 172..195 CDD:275380 6/22 (27%)
leucine-rich repeat 196..219 CDD:275380 6/22 (27%)
TPKR_C2 228..277 CDD:301599 16/63 (25%)
IG_like 294..390 CDD:214653
Ig 296..387 CDD:143165
TrilNP_080093.1 LRR_RI <11..194 CDD:238064 54/185 (29%)
leucine-rich repeat 37..57 CDD:275378 6/19 (32%)
LRR 1 61..81 6/19 (32%)
LRR_8 84..143 CDD:290566 21/58 (36%)
LRR 2 84..105 4/20 (20%)
leucine-rich repeat 85..108 CDD:275380 5/22 (23%)
LRR 3 108..129 10/20 (50%)
leucine-rich repeat 109..132 CDD:275380 11/22 (50%)
LRR 4 132..153 8/20 (40%)
leucine-rich repeat 133..156 CDD:275380 8/22 (36%)
LRR_8 156..215 CDD:290566 17/60 (28%)
LRR 5 156..177 6/20 (30%)
leucine-rich repeat 157..180 CDD:275380 6/22 (27%)
LRR 6 180..201 5/20 (25%)
leucine-rich repeat 181..204 CDD:275380 6/22 (27%)
LRR 7 204..223 6/20 (30%)
leucine-rich repeat 205..230 CDD:275380 7/26 (27%)
LRR_RI 229..>364 CDD:238064 12/45 (27%)
LRR_8 229..289 CDD:290566 12/45 (27%)
LRR 8 230..251 3/20 (15%)
leucine-rich repeat 231..254 CDD:275380 4/22 (18%)
LRR 9 254..275 7/20 (35%)
leucine-rich repeat 255..278 CDD:275380 7/19 (37%)
LRR 10 278..298
leucine-rich repeat 279..302 CDD:275380
LRR_8 302..359 CDD:290566
LRR 11 302..323
leucine-rich repeat 303..323 CDD:275380
LRR 12 326..347
leucine-rich repeat 327..350 CDD:275380
TPKR_C2 359..406 CDD:301599
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 412..462
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 483..563
FN3 587..659 CDD:214495
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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