DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek4 and lrrc38a

DIOPT Version :9

Sequence 1:NP_001260435.1 Gene:kek4 / 34718 FlyBaseID:FBgn0032484 Length:649 Species:Drosophila melanogaster
Sequence 2:XP_021325623.1 Gene:lrrc38a / 567935 ZFINID:ZDB-GENE-080327-12 Length:290 Species:Danio rerio


Alignment Length:211 Identity:57/211 - (27%)
Similarity:92/211 - (43%) Gaps:35/211 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    31 FRSASADWLLDCG-----NCHCKWNSGKKTADCRNLSLSGVPEYLSPEVQVLDLSHNHIFYLEEN 90
            |.:..:..|:.||     :|.|   ....|.||....|:.:|:.:..:|:.|.||:|.|.::..:
Zfish    11 FLALLSSTLISCGYNCPSSCLC---PDHHTVDCTGQGLTRLPDSIPLDVRRLLLSNNWIPWIPSD 72

  Fly    91 AFLTTHLQNLQKLLIRNGTLKYLNQRSFTQLQILIELDLSNNLLVDLLPNVFDCLSKVRAIFLNG 155
             ||..:..                         |:.|||.||.|..|.|......|::..:.|..
Zfish    73 -FLVLYSD-------------------------LVYLDLRNNSLTRLEPGTLSTSSRLVYLDLGS 111

  Fly   156 NLLQALRHGVFRNLKYLHKIELKRNRLVSIDAK-AFVGVPLLSQIYLDNNELTKLRVESFQDLTK 219
            |.|..:..|.|...:.|.|:.|..|..:::.:| ||:|:..|.::.|::|.|:.|.||....|..
Zfish   112 NNLTEIPSGTFGESRSLIKLRLGNNPYLNMVSKDAFLGLTSLRELELESNALSGLDVEVLSQLPS 176

  Fly   220 LTALSLVENPWNCTCD 235
            |..:.|..|||.|.|:
Zfish   177 LRVIRLEGNPWVCNCN 192

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek4NP_001260435.1 leucine-rich repeat 75..99 CDD:275380 7/23 (30%)
LRR_8 99..158 CDD:290566 12/58 (21%)
leucine-rich repeat 100..123 CDD:275380 0/22 (0%)
leucine-rich repeat 124..147 CDD:275380 9/22 (41%)
LRR_8 146..206 CDD:290566 17/60 (28%)
leucine-rich repeat 148..171 CDD:275380 5/22 (23%)
leucine-rich repeat 172..195 CDD:275380 8/23 (35%)
leucine-rich repeat 196..219 CDD:275380 8/22 (36%)
TPKR_C2 228..277 CDD:301599 5/8 (63%)
IG_like 294..390 CDD:214653
Ig 296..387 CDD:143165
lrrc38aXP_021325623.1 LRRNT 26..56 CDD:214470 7/32 (22%)
leucine-rich repeat 36..58 CDD:275380 6/21 (29%)
leucine-rich repeat 59..79 CDD:275380 7/20 (35%)
PLN00113 <60..>185 CDD:331614 39/150 (26%)
leucine-rich repeat 80..103 CDD:275380 9/22 (41%)
LRR_8 102..163 CDD:316378 17/60 (28%)
leucine-rich repeat 104..127 CDD:275380 5/22 (23%)
leucine-rich repeat 128..152 CDD:275380 8/23 (35%)
leucine-rich repeat 153..176 CDD:275380 8/22 (36%)
TPKR_C2 185..>219 CDD:326558 5/8 (63%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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