Protein Alignment kek4 and LOC563710

DIOPT Version :10

• Sequence 1: NP_609615.2
• Gene: kek4 / 34718
• FlyBaseID: FBgn0032484
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_692159.4
• Gene: LOC563710 / 563710
• -ID: -
• Length: 635
• Species: Danio rerio
• Alignment Length: 606
• Identity: 136/606 - (22%)
• Similarity: 221/606 - (36%)
• Gaps: 190/606 - (31%)

  Fly    69 YLSPEVQVLDLSHNHIFYLEENAFLTTHLQNLQKLL---IRNGTLKYLNQRSFTQLQILIELDLS 130
            :|.|.::.||||:|.:..|:...|     |.|:|||   :|:.:||.|..|.|...:.|..|||.
Zfish   127 HLVPNLRNLDLSYNKLQALQPGQF-----QGLRKLLSLHMRSNSLKNLPSRLFQDCRNLEFLDLG 186

  Fly   131 NNLLVDLLPNVFDCLSK------------------------VRAIFLNGNLLQALRHGVFRNLKY 171
            .|.|..:..|....|.|                        :||::|..|.::.:..|:......
Zfish   187 YNRLRSITRNSMSGLLKLTELHIEHNQFSKINFFNFPRFYNLRALYLQWNRIRTMSEGLTWMWTS 251

  Fly   172 LHKIELKRNRLVSIDAKAFVGVPLLSQIYLDNNELTKLRVESFQDLTKLTALSLVENPWNC---T 233
            |.|::|..|.|..|||:.:..:|.|..:.||:|:|..:..|:....|.|||:||..|.|:|   .
Zfish   252 LQKLDLSGNDLQEIDAEVYRAMPNLQTLNLDSNKLVNVSQEAVDAWTSLTAISLAGNMWDCGPVV 316

  Fly   234 CDLQMFRDFVIG---MNLYTPPTSCHYPLQLRGRLWIEDQPEAFACKPKIVYPTLSTSINTSKEN 295
            |.|..:.....|   :|:.     |..|.:::|.. :.|..:|..
Zfish   317 CPLVAWMRTFRGNKEINMI-----CASPKEVQGEK-VLDAVDANG-------------------- 355

  Fly   296 VTLICRV-HGSPNTV-------IAWDYTNQVYESRSKPVKSLQKQRIYIELLREDESKIRKFGHD 352
               :||: ..:|:|:       :|:..|         |..||      :..|:..:|: |..|
Zfish   356 ---VCRIAPATPSTIFVPSTPFVAFSQT---------PASSL------VPTLKSGDSR-RVHG-- 399

  Fly   353 VFVSRLTIVNARKSDEGVYTCLAENPGGKDSVHISVVVQKDMERISLIDSNFFAIVCLIAMGFLS 417
                        .|.||..:.:...|.....       ::|.|.:|     |..||......|||
Zfish   400 ------------TSLEGSTSSVPSQPDVPPQ-------EQDFEPVS-----FHKIVAGSVALFLS 440

  Fly   418 MSILFSLVTCLIFKRFKQFHPGQHTYLQPTSLPVQSPGSEEATAISALSSGVIRESKIVLDPLSA 482
            ::::. ||..:.:||:    |.....||..|...:....:.            ||::      ..
Zfish   441 VAMIL-LVIYVSWKRY----PSSVKQLQENSAAARKRRKKS------------RETE------RT 482

  Fly   483 INEPSNKNYTLFKTSNSNGSEYMHTRNYKDVRLNSN---TYTENLDNQAESISSRNRELYSNIAG 544
            ::.|..:.|..:|.:|:.|:         ||.:|..   |||                    |:|
Zfish   483 LSTPLQEYYVDYKPNNTEGT---------DVLVNGTGPCTYT--------------------ISG 518

  Fly   545 DREKEELKQKDELD--------KDSRQS------SLQSTGCSRKKGQIDELQPDLLPSTQPTAL- 594
            .||.|...|...|.        .|..|:      ::...|..:....::||.|....:.|..||
Zfish   519 SRECEVPHQMSTLTFYRYEQPIVDYCQAHQPLRLNMSYEGPPQSLEGLEELPPRERSTIQTVALP 583

  Fly   595 --KNINE-TFGPSAKKAEVNP 612
              ..||. |.||.:..::..|
Zfish   584 AVPTINTGTTGPCSPPSQRAP 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek4	NP_609615.2	LRR	59..>228	CDD:443914	55/185 (30%)
		leucine-rich repeat	75..99	CDD:275380	7/23 (30%)
		LRR_8	98..158	CDD:404697	24/86 (28%)
		leucine-rich repeat	100..123	CDD:275380	10/25 (40%)
		leucine-rich repeat	124..147	CDD:275380	8/22 (36%)
		leucine-rich repeat	148..171	CDD:275380	5/22 (23%)
		leucine-rich repeat	172..195	CDD:275380	8/22 (36%)
		leucine-rich repeat	196..219	CDD:275380	6/22 (27%)
		LRRCT	228..277	CDD:214507	12/54 (22%)
		IG_like	294..390	CDD:214653	17/103 (17%)
		Ig strand B	296..300	CDD:409353	0/3 (0%)
		Ig strand C	309..323	CDD:409353	2/20 (10%)
		Ig strand E	356..360	CDD:409353	0/3 (0%)
		Ig strand F	370..375	CDD:409353	0/4 (0%)
		Ig strand G	383..386	CDD:409353	0/2 (0%)
LOC563710	XP_692159.4	leucine-rich repeat	60..83	CDD:275380
		LRR	63..>308	CDD:443914	55/185 (30%)
		leucine-rich repeat	84..107	CDD:275380
		leucine-rich repeat	108..131	CDD:275380	1/3 (33%)
		leucine-rich repeat	132..155	CDD:275380	9/27 (33%)
		leucine-rich repeat	156..179	CDD:275380	8/22 (36%)
		leucine-rich repeat	180..203	CDD:275380	8/22 (36%)
		leucine-rich repeat	204..227	CDD:275380	0/22 (0%)
		leucine-rich repeat	228..251	CDD:275380	5/22 (23%)
		leucine-rich repeat	252..275	CDD:275380	8/22 (36%)