Protein Alignment kek4 and slit1b

DIOPT Version :10

• Sequence 1: NP_609615.2
• Gene: kek4 / 34718
• FlyBaseID: FBgn0032484
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001030147.1
• Gene: slit1b / 561685
• ZFINID: ZDB-GENE-030722-4
• Length: 1532
• Species: Danio rerio
• Alignment Length: 346
• Identity: 80/346 - (23%)
• Similarity: 148/346 - (42%)
• Gaps: 65/346 - (18%)

  Fly    41 DCGN-------CHCKWNSGKKTADCRNLSLSGVPEYLSPEVQVLDLSHNHIFYLEENAFL--TTH 96
            ||.:       |.|:    ....||.||.|:..||:|......|.|::|.:..||.....  .||
Zfish   503 DCNSKPVCPPKCRCE----ATVVDCSNLRLTKFPEHLPLSTTELRLNNNDLSILEATGLFRPLTH 563

  Fly    97 LQNLQKLLIRNGTLKYLNQRSFTQLQILIELDLSNNLLVDLLPNVFDCLSKVRAIFLNGNLLQAL 161
            |:                           :::||||.:.::....|:..|.|..:.|..|||.::
Zfish   564 LK---------------------------KINLSNNKITEIEDGAFEGASSVVELHLTANLLVSV 601

  Fly   162 RHGVFRNLKYLHKIELKRNRLVSIDAKAFVGVPLLSQIYLDNNELTKLRVESFQDLTKLTALSLV 226
            |.|:||.:..|..:.|:.|.:..:...:|.|:..:..:.|.:|:|:.:...:|..|..|:.|:|:
Zfish   602 RGGMFRGMDGLRMLMLRNNHIRCVHNSSFSGLQNVRLLSLYDNQLSTIMPGAFDSLPNLSTLNLL 666

  Fly   227 ENPWNCTCDLQMFRDFVIGMNLYTPPTSCHYPLQLRGRLWIED--QPEAF----------ACKPK 279
            .||::|.|.|....:::....:.|....|..|..|| .:.::|  :|:..          :|.||
Zfish   667 ANPFSCDCRLSWLGEWLRSRQIVTGNPRCQNPAFLR-EIPLQDVAKPDFICDKDVLEQDVSCIPK 730

  Fly   280 IVYPTLSTSINT----SKENVTLICRVHGSPNTVIAWDYTNQVYESRSKPVKSLQKQRIYIELLR 340
            ...|...|.:::    |.::::.:.|  |.|..|........|:.|..:.:.:.::    ::||.
Zfish   731 PQCPEQCTCVDSVVRCSNKHLSALPR--GVPLNVTELYLDGNVFVSIPQELSAFRQ----LQLLD 789

  Fly   341 EDESKIRKFGHDVF--VSRLT 359
            ...:||....:..|  :|:||
Zfish   790 LSNNKISSLTNTSFTNMSQLT 810

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek4	NP_609615.2	LRR	59..>228	CDD:443914	42/170 (25%)
		leucine-rich repeat	75..99	CDD:275380	8/25 (32%)
		LRR_8	98..158	CDD:404697	9/59 (15%)
		leucine-rich repeat	100..123	CDD:275380	0/22 (0%)
		leucine-rich repeat	124..147	CDD:275380	5/22 (23%)
		leucine-rich repeat	148..171	CDD:275380	9/22 (41%)
		leucine-rich repeat	172..195	CDD:275380	5/22 (23%)
		leucine-rich repeat	196..219	CDD:275380	5/22 (23%)
		LRRCT	228..277	CDD:214507	12/60 (20%)
		IG_like	294..390	CDD:214653	14/68 (21%)
		Ig strand B	296..300	CDD:409353	0/3 (0%)
		Ig strand C	309..323	CDD:409353	3/13 (23%)
		Ig strand E	356..360	CDD:409353	3/4 (75%)
		Ig strand F	370..375	CDD:409353
		Ig strand G	383..386	CDD:409353
slit1b	NP_001030147.1	LRR	<40..>257	CDD:443914
		leucine-rich repeat	41..58	CDD:275380
		leucine-rich repeat	60..83	CDD:275380
		leucine-rich repeat	84..107	CDD:275380
		leucine-rich repeat	108..131	CDD:275380
		leucine-rich repeat	132..155	CDD:275380
		leucine-rich repeat	156..179	CDD:275380
		leucine-rich repeat	180..203	CDD:275380
		leucine-rich repeat	204..247	CDD:275380
		leucine-rich repeat	248..330	CDD:275380
		LRR	<288..>437	CDD:443914
		leucine-rich repeat	331..354	CDD:275380
		leucine-rich repeat	355..375	CDD:275380
		leucine-rich repeat	403..426	CDD:275380
		PCC	408..>471	CDD:188093
		leucine-rich repeat	427..482	CDD:275380
		LRRNT	510..536	CDD:396168	9/29 (31%)
		leucine-rich repeat	519..538	CDD:275380	8/18 (44%)
		LRR	524..>846	CDD:443914	74/321 (23%)
		leucine-rich repeat	539..563	CDD:275380	5/23 (22%)
		leucine-rich repeat	564..587	CDD:275380	6/49 (12%)
		leucine-rich repeat	588..611	CDD:275380	9/22 (41%)
		leucine-rich repeat	612..635	CDD:275380	5/22 (23%)
		leucine-rich repeat	636..659	CDD:275380	5/22 (23%)
		leucine-rich repeat	660..753	CDD:275380	21/93 (23%)
		LRRNT	732..764	CDD:214470	7/33 (21%)
		leucine-rich repeat	754..784	CDD:275380	6/31 (19%)
		leucine-rich repeat	785..808	CDD:275380	5/22 (23%)
		leucine-rich repeat	809..829	CDD:275380	2/2 (100%)
		leucine-rich repeat	833..856	CDD:275380
		PCC	841..>979	CDD:188093
		EGF_CA	968..1001	CDD:238011
		EGF_CA	1003..1039	CDD:238011
		EGF_CA	<1051..1079	CDD:238011
		EGF_CA	1082..1118	CDD:238011
		LamG	1160..1314	CDD:238058