Protein Alignment kek4 and lrfn2b

DIOPT Version :10

• Sequence 1: NP_609615.2
• Gene: kek4 / 34718
• FlyBaseID: FBgn0032484
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_009292765.2
• Gene: lrfn2b / 558484
• ZFINID: ZDB-GENE-121214-111
• Length: 781
• Species: Danio rerio
• Alignment Length: 707
• Identity: 152/707 - (21%)
• Similarity: 239/707 - (33%)
• Gaps: 209/707 - (29%)

  Fly    54 KTADCRNLS-----------LSGVPEYLSPEVQVLDLSHNHIFYLEENAFLTTHLQNLQKLLIRN 107
            |...|:|||           |..||..:......|.|..|.|..:.:..|  .::.:|..|.:..
Zfish    23 KYCACQNLSESLGTLCPAKGLLFVPSDIDRSTVELRLGGNFILRITQQDF--ANMTDLVDLTLSR 85

  Fly   108 GTLKYLNQRSFTQLQILIELDLSNNLLVDLLPNVFDCLSKVRAIFLNGNL--------------- 157
            .|:.|:...||..|:.|..|.:.||.|.:|.|:....|..::.:.||.|.
Zfish    86 NTISYIQPFSFGDLETLRSLHMDNNRLTELGPDDLRGLISLQHLILNNNQLSRVSERAFEDLAAT 150

  Fly   158 ----------LQALRHGVFRNLKYLHKIELKRNRLVSIDAKAFVGVPLLSQIYLDNNELTKLRVE 212
                      ||||.....|.:..||::.|..|.|..|....||.:..|:::.|.:|.|.||..:
Zfish   151 LEDLDLSYNNLQALPWHSVRQMINLHQMSLDHNLLDYIPEGTFVDLERLARLDLTSNRLQKLPPD 215

  Fly   213 SF----QDLTKLT-------ALSLVENPWNCTCDLQMFRDFVIGMNLYTPPTSCHYPLQLRGRLW 266
            ..    ||...:|       :||:..||.:|.|:|..||......:|.|    |..|..|:||.:
Zfish   216 PIFARAQDSEVMTTPFAPQLSLSIGGNPLHCNCELLWFRRLERDDDLET----CASPPGLKGRYF 276

  Fly   267 IEDQPEAFACKPKIVYPTLSTSINTSKENVTLICRVHGSPNTVIAWDYTNQVYESRSKPVKSLQK 331
            ...:...|.|:..::.......:....:..:|.|...|.|...|.|
Zfish   277 WNVREHEFLCEQPLITQHTHKLLVLEGQTASLRCDAIGDPIPTIHW------------------- 322

  Fly   332 QRIYIELLREDESKIRKFGHD--VFVSR---LTIVNARKSDEGVYTCLAENPGGKD--SVHISVV 389
                  :..||    |..|:.  ..|.|   |.|:.....|.|.:||:|.|..|:.  ||.:|::
Zfish   323 ------VTPED----RLLGNSSRTVVYRNGTLEILITTSKDSGTFTCIAANLAGESTASVELSII 377

  Fly   390 -----------VQKDMERISLID--------------------SNFFAIVCLI--AMGFLSMSI- 420
                       ..:...|:|.|.                    |...|:..|:  .:|..:..:
Zfish   378 QLPHISNGTGQASQPKSRLSDITGGSRTNKGIPKGQPEKAVSVSEVTAVAALVRWTVGKTAPKVK 442

  Fly   421 LFSL-VTC-----LIFKRFKQFHPGQHTYLQPTSLPVQSPGSEEATAISALSSGVIRESKIVLDP 479
            :|.| ..|     ||::..                    |.|.:|..|:.|.||    ::..|..
Zfish   443 MFQLQYNCSDDEVLIYRMI--------------------PSSSKAFHITNLVSG----TRYDLCV 483

  Fly   480 LSAINEPSNKNYTLFKTSNSNGSEYMHTRN----------------------------------- 509
            |:|..:.:    |....:|..|....:||:
Zfish   484 LAAWEDSA----TTLTATNVVGCVEFYTRDDYTQCQSLQGQLLGGTMILVVGGVIVATLLVFIVI 544

  Fly   510 ----YKDVRLNSNTYTENLDNQAESISSRN-RELYSN---IAGDREKEELKQKDELDK---DSRQ 563
                ||......:.....|.:.:|:.|..| ..|..|   :.|.:||..:..:||:.|   .|.|
Zfish   545 LMVRYKAGDGGGDAPVCKLSDSSETYSQTNGGRLGQNGVPLPGPKEKSTVTMRDEVVKFKCGSLQ 609

  Fly   564 SSLQSTGCSRKKGQIDELQP-----DLLPSTQPTALKNINETFGPSAKKAEVNPRSK 615
            ||..|:..|..........|     ::|.|..|....||::..| :....|:..:||
Zfish   610 SSSSSSSSSSGSADATSYSPNSALANILRSAPPKQHNNIDQLLG-AFTSLELRGQSK 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek4	NP_609615.2	LRR	59..>228	CDD:443914	53/215 (25%)
		leucine-rich repeat	75..99	CDD:275380	5/23 (22%)
		LRR_8	98..158	CDD:404697	18/84 (21%)
		leucine-rich repeat	100..123	CDD:275380	7/22 (32%)
		leucine-rich repeat	124..147	CDD:275380	8/22 (36%)
		leucine-rich repeat	148..171	CDD:275380	8/47 (17%)
		leucine-rich repeat	172..195	CDD:275380	8/22 (36%)
		leucine-rich repeat	196..219	CDD:275380	8/26 (31%)
		LRRCT	228..277	CDD:214507	15/48 (31%)
		IG_like	294..390	CDD:214653	24/113 (21%)
		Ig strand B	296..300	CDD:409353	1/3 (33%)
		Ig strand C	309..323	CDD:409353	2/13 (15%)
		Ig strand E	356..360	CDD:409353	2/6 (33%)
		Ig strand F	370..375	CDD:409353	2/4 (50%)
		Ig strand G	383..386	CDD:409353	2/2 (100%)
lrfn2b	XP_009292765.2	None