Protein Alignment kek4 and slitrk4

DIOPT Version :10

• Sequence 1: NP_609615.2
• Gene: kek4 / 34718
• FlyBaseID: FBgn0032484
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_021336820.1
• Gene: slitrk4 / 558123
• ZFINID: ZDB-GENE-140303-1
• Length: 830
• Species: Danio rerio
• Alignment Length: 539
• Identity: 113/539 - (20%)
• Similarity: 202/539 - (37%)
• Gaps: 145/539 - (26%)

  Fly    42 CGNCHCKWNSGKKTADCRNLSLSGVPEYLSP---EVQVLDLSHNHIFYLEENAFLT-TH------ 96
            |..|.|.........:|..:::.. |..|.|   .:..|:..:|.::.|..|:|:. ||
Zfish    27 CSACSCMSIENVLYVNCEKITVYR-PTQLHPPASSLYHLNFQNNLLYILYPNSFVNFTHAVSLQL 90

  Fly    97 ----LQN-----------LQKLLIRNGTLKYLNQRSFTQLQILIELDLSNNLLVDLLPNVFDCLS 146
                |||           |::|.:.|..||.|...:|..::.|..|....||:..:....|:.|.
Zfish    91 GNNKLQNIEGGAFVGLSALKQLHLNNNELKELRADTFRGIENLEYLQADYNLIKFIEKGAFNKLH 155

  Fly   147 KVRAIFLNGNLLQALRHGVFRNLKYLHKIELKRNRLVSIDAKAFVGVPLLSQIYLDNNELTKLRV 211
            |::.:.||.||:|:|...:||.....| ::::.||:..:   .::||
Zfish   156 KLKVLILNDNLIQSLPENIFRFASLTH-LDIRGNRIQKL---PYLGV------------------ 198

  Fly   212 ESFQDLTKLTALSLVENPWNCTCDLQMFRDFVIGM--NLYTPPTSCHYPLQLRGRLWIE------ 268
              .:.:.::..|.|.:|||||||||...:.::..|  |::.....|..|..|.|||..|
Zfish   199 --LEHIGRIVELQLDDNPWNCTCDLLPLKAWLENMPYNIFIGEAICETPSDLYGRLLKETNKQEL 261

  Fly   269 ---------------DQPEAFACKPKIVYPTLSTSINTSKENVTLICRVHGSPNTVIAWD---YT 315
                           .|||.......:...|::..: |.....|...:::|  |.::|.:   ..
Zfish   262 CPMGTGSDFDVRMPPSQPEGGLTMSNVAPSTIAPLV-TKAPKTTNPSKIYG--NGIVAGNPAGKN 323

  Fly   316 NQV--YESRSKPVKSLQKQRIYIELLREDESKIRKFGHDVFVSRLTIVNARKSDEGV-YTCLAEN 377
            .|:  |::|..|:...|.                           ....|..||.|: .:|...|
Zfish   324 GQIVSYQTRIPPLSCPQP---------------------------CTCKAHPSDFGISVSCQERN 361

  Fly   378 ----------PGGKDSVHISVVVQKDMERISLIDSNFFAIVCLIAMGFLSMSI----LFSLVTCL 428
                      |.....:|:|....:|   ||..|...|..:.|:.:|...:|.    :|:.:|.|
Zfish   362 IQSLADLIPKPPNAKKLHLSGNYIRD---ISPTDFQGFEGLDLLHLGSNQISTVQKGVFANLTNL 423

  Fly   429 --IF---KRFKQFHPG--------QHTYLQPTSLPVQSPGSEEA---TAISALSSGVIRESKIVL 477
              ::   .:.:|.||.        |:.||:..::.....|:.::   ..:..|::.|:|.....:
Zfish   424 RRLYLNGNQLEQLHPEMFLGLSNLQYLYLEYNAIKEVLAGTFDSMPNLQLLYLNNNVLRSLPAYI 488

  Fly   478 ---DPLSAINEPSNKNYTL 493
               ..|:.:|..:|...||
Zfish   489 FAGVSLARLNLKNNHFMTL 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek4	NP_609615.2	LRR	59..>228	CDD:443914	42/193 (22%)
		leucine-rich repeat	75..99	CDD:275380	8/34 (24%)
		LRR_8	98..158	CDD:404697	19/70 (27%)
		leucine-rich repeat	100..123	CDD:275380	7/22 (32%)
		leucine-rich repeat	124..147	CDD:275380	6/22 (27%)
		leucine-rich repeat	148..171	CDD:275380	8/22 (36%)
		leucine-rich repeat	172..195	CDD:275380	5/22 (23%)
		leucine-rich repeat	196..219	CDD:275380	0/22 (0%)
		LRRCT	228..277	CDD:214507	21/71 (30%)
		IG_like	294..390	CDD:214653	18/111 (16%)
		Ig strand B	296..300	CDD:409353	1/3 (33%)
		Ig strand C	309..323	CDD:409353	3/18 (17%)
		Ig strand E	356..360	CDD:409353	0/3 (0%)
		Ig strand F	370..375	CDD:409353	1/5 (20%)
		Ig strand G	383..386	CDD:409353	0/2 (0%)
slitrk4	XP_021336820.1	leucine-rich repeat	38..60	CDD:275380	4/22 (18%)
		LRR	<59..>213	CDD:443914	39/177 (22%)
		leucine-rich repeat	61..84	CDD:275380	5/22 (23%)
		leucine-rich repeat	87..108	CDD:275380	3/20 (15%)
		leucine-rich repeat	109..132	CDD:275380	7/22 (32%)
		leucine-rich repeat	133..156	CDD:275380	6/22 (27%)
		leucine-rich repeat	157..179	CDD:275380	8/21 (38%)
		leucine-rich repeat	180..204	CDD:275380	5/47 (11%)
		leucine-rich repeat	205..364	CDD:275380	40/188 (21%)
		LRRCT	213..>253	CDD:214507	16/39 (41%)
		LRR	<361..>527	CDD:443914	30/150 (20%)
		leucine-rich repeat	365..398	CDD:275380	8/35 (23%)
		leucine-rich repeat	399..422	CDD:275380	4/22 (18%)
		leucine-rich repeat	423..446	CDD:275380	4/22 (18%)
		leucine-rich repeat	447..468	CDD:275380	4/20 (20%)
		leucine-rich repeat	471..493	CDD:275380	3/21 (14%)
		leucine-rich repeat	494..518	CDD:275380	5/14 (36%)
		PCC	498..>559	CDD:188093	4/10 (40%)