Protein Alignment kek4 and slit1a

DIOPT Version :10

• Sequence 1: NP_609615.2
• Gene: kek4 / 34718
• FlyBaseID: FBgn0032484
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001030140.1
• Gene: slit1a / 556123
• ZFINID: ZDB-GENE-030722-3
• Length: 1524
• Species: Danio rerio
• Alignment Length: 345
• Identity: 84/345 - (24%)
• Similarity: 137/345 - (39%)
• Gaps: 65/345 - (18%)

  Fly    41 DCGN-------CHCKWNSGKKTADCRNLSLSGVPEYLSPEVQVLDLSHNHIFYLEE-NAFLT-TH 96
            ||.|       |.|:.|    ..||.||.|..:||::........|::|.|..:|. .||.| ||
Zfish   499 DCNNDPVCPAKCRCESN----VVDCSNLRLDRIPEHVPASTTEPRLNNNEITTIEAMGAFKTLTH 559

  Fly    97 LQNLQKLLIRNGTLKYLNQRSFTQLQILIELDLSNNLLVDLLPNVFDCLSKVRAIFLNGNLLQAL 161
            |:                           :::||||.:.::....|:..|.|..:.|..|.|...
Zfish   560 LK---------------------------KINLSNNKISEIEDGAFEGASSVNELHLTANQLDLA 597

  Fly   162 RHGVFRNLKYLHKIELKRNRLVSIDAKAFVGVPLLSQIYLDNNELTKLRVESFQDLTKLTALSLV 226
            ..|:||.|:.|..:.|:.||:..|...:|.|:..:..:.|.:|.||.:...:|..|..|:.|:|:
Zfish   598 HSGMFRGLEGLRMLMLRNNRISCIHNNSFTGLHNVRLLSLYDNTLTTIAPGAFDTLQSLSTLNLL 662

  Fly   227 ENPWNCTCDLQMFRDFVIGMNLYTPPTSCHYPLQLR---------GRLWIEDQPEAFACKPKIVY 282
            .||:||.|.|.....::....:.|....||.|..|:         .....||..|..:|.|.:..
Zfish   663 ANPFNCNCRLAWLSSWLRNRKIVTGNPRCHRPAFLKEIPLQDVAAPDFRCEDDHEDVSCAPPVHC 727

  Fly   283 PTLSTSINTSKENVTLICRVH------GSPNTVIAWDYTNQVYESRSKPVKSLQKQRIYIELLRE 341
            |...|.:    |:|......|      |:|..:...........:..|.:.|.:.    ::|:..
Zfish   728 PADCTCL----ESVVRCSNKHLQALPKGTPRNITELYLDGNQLSTVPKELSSFKS----LQLVDL 784

  Fly   342 DESKIRKFGHDVF--VSRLT 359
            ..::|....:..|  :|:||
Zfish   785 SNNRISSLTNSSFTNMSQLT 804

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek4	NP_609615.2	LRR	59..>228	CDD:443914	45/170 (26%)
		leucine-rich repeat	75..99	CDD:275380	10/25 (40%)
		LRR_8	98..158	CDD:404697	9/59 (15%)
		leucine-rich repeat	100..123	CDD:275380	0/22 (0%)
		leucine-rich repeat	124..147	CDD:275380	5/22 (23%)
		leucine-rich repeat	148..171	CDD:275380	8/22 (36%)
		leucine-rich repeat	172..195	CDD:275380	7/22 (32%)
		leucine-rich repeat	196..219	CDD:275380	6/22 (27%)
		LRRCT	228..277	CDD:214507	14/57 (25%)
		IG_like	294..390	CDD:214653	13/74 (18%)
		Ig strand B	296..300	CDD:409353	1/3 (33%)
		Ig strand C	309..323	CDD:409353	0/13 (0%)
		Ig strand E	356..360	CDD:409353	3/4 (75%)
		Ig strand F	370..375	CDD:409353
		Ig strand G	383..386	CDD:409353
slit1a	NP_001030140.1	LRR	<25..>245	CDD:443914
		leucine-rich repeat	36..55	CDD:275380
		leucine-rich repeat	56..79	CDD:275380
		leucine-rich repeat	80..103	CDD:275380
		leucine-rich repeat	104..127	CDD:275380
		leucine-rich repeat	128..151	CDD:275380
		leucine-rich repeat	152..175	CDD:275380
		leucine-rich repeat	176..199	CDD:275380
		leucine-rich repeat	200..327	CDD:275380
		LRR	<282..>454	CDD:443914
		leucine-rich repeat	328..351	CDD:275380
		leucine-rich repeat	352..372	CDD:275380
		leucine-rich repeat	400..423	CDD:275380
		leucine-rich repeat	424..521	CDD:275380	8/25 (32%)
		LRR	515..>813	CDD:443914	79/329 (24%)
		leucine-rich repeat	522..559	CDD:275380	11/36 (31%)
		leucine-rich repeat	560..583	CDD:275380	6/49 (12%)
		leucine-rich repeat	584..607	CDD:275380	8/22 (36%)
		leucine-rich repeat	608..631	CDD:275380	7/22 (32%)
		leucine-rich repeat	632..653	CDD:275380	5/20 (25%)
		leucine-rich repeat	656..747	CDD:275380	24/94 (26%)
		leucine-rich repeat	748..778	CDD:275380	4/29 (14%)
		leucine-rich repeat	779..802	CDD:275380	3/22 (14%)
		leucine-rich repeat	803..823	CDD:275380	2/2 (100%)
		leucine-rich repeat	827..850	CDD:275380
		PCC	835..>907	CDD:188093
		EGF_CA	920..955	CDD:238011
		EGF_CA	958..996	CDD:238011
		EGF_CA	998..1034	CDD:238011
		EGF_CA	1078..1112	CDD:238011
		LamG	1179..1312	CDD:214598