Protein Alignment kek4 and lrit1b

DIOPT Version :10

• Sequence 1: NP_609615.2
• Gene: kek4 / 34718
• FlyBaseID: FBgn0032484
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001036218.1
• Gene: lrit1b / 553432
• ZFINID: ZDB-GENE-060616-45
• Length: 654
• Species: Danio rerio
• Alignment Length: 623
• Identity: 133/623 - (21%)
• Similarity: 228/623 - (36%)
• Gaps: 138/623 - (22%)

  Fly    42 CGNC--HC-----KWNSGKKTAD--CRNLSLSGVPEYLSPEVQVLDLSHNHIFYLEENAFLTTHL 97
            ||:|  .|     |.:.|.|:..  |.:..|:.:|:...     ||.|
Zfish    20 CGSCPAQCSCFYHKLSDGSKSRSVLCNDPDLTDIPDNFP-----LDAS----------------- 62

  Fly    98 QNLQKLLIRNGTLKYLNQRSFTQLQILIELDLSNNLLVDLLPNVFDCLSKVRAIFLNGNLLQALR 162
                ||.|...:|..::...|.||..|..|.:|.|.|..:.|:.|..|..:..:.::||:|.:..
Zfish    63 ----KLRIEKTSLSRISSAPFQQLSSLEYLWISFNSLSSISPDTFRGLYALDELRMDGNVLTSFP 123

  Fly   163 HGVFRNLKYLHKIELKRNRLVSIDAKAFVGVPLLSQIYLDNNELTKLRVES----FQDLTKLTA- 222
            .....::..|..::|..|::.||.|:|.:.:..|:.:.|.:|.||.:..|.    |.....|.|
Zfish   124 WECLLDMPSLRLLDLHNNKISSIPAEATLYIRNLTYLDLSSNSLTTVPPEVLMSWFSPKPPLDAE 188

  Fly   223 -----LSLVENPWNCTC---DLQMFRDFVIGMNLYTPPTS---------CHYPLQLRGRLWIEDQ 270
                 |.|.:|||.|.|   ||..|:.|        |.:|         |..|..|.|.|:  ..
Zfish   189 GSRMILGLHDNPWQCDCRLFDLVQFQKF--------PSSSVAFIDTGLRCAEPESLSGVLF--SD 243

  Fly   271 PEAFACKPKIVYPTLSTSINTSKENVTLICRVHGSPNTVIAWDYTNQVYESRSKPVKSLQKQRIY 335
            .|...|:...|:..::...::...||.|.|...|.|...::|      ..:..||:....:|.:.
Zfish   244 AELRRCQIPRVHTAVARVRSSIGNNVLLRCGTIGVPIPELSW------ARADGKPMNGTVQQEVS 302

  Fly   336 IELLREDESKIRKFGHDVFVSRLTIVNARKSDEGVYTCLAEN-PGGKDSVHISVVVQKDMERISL 399
            .|              .:..|.|::......|.|.|.|.|.| .|..|::            |||
Zfish   303 KE--------------GIIWSILSVPAVSYRDSGKYVCKATNFVGSADAI------------ISL 341

  Fly   400 IDSNFFAIVCLIAM--------GFLSMSILFSLVTCLIFKRFKQFHPGQHTYLQPTSLPVQSP-G 455
            :.|:.:.|...:|.        ||...:....|:.        ::.|...:...|...|:.|| |
Zfish   342 VISDTWQIDEAVAKRSHGKKSGGFGRAAYQEKLIA--------RYVPPSTSAAVPIIEPLNSPQG 398

  Fly   456 SE----EATAISALSSGVIRESKIVLDPLS-----AINEPSNKNYTLFKTSNSNGSEYMHTRNYK 511
            |.    |:.::||.:|.:..:.|....|:.     |:......|.....:|...|.|....|:.|
Zfish   399 SSSVQIESYSVSADASKLKPKPKPTAPPVGQTEPVALQRDVLNNLEPNASSLQQGPERRVVRSVK 463

  Fly   512 DVRLNSNTYTENLDNQAESISSRNRELYSNIAGDREKEELK---QKDELDKDSRQSSLQSTGCSR 573
            .:....:|.:.|......:.::....||: :.|:|:...:.   .|:.:..:......:...|..
Zfish   464 VIGDTDHTVSLNWRAPTATNTTSFSVLYA-VFGERDMRRINVGPGKNRITIEGLVPKTKYIACVC 527

  Fly   574 KKGQIDELQPDLLPSTQPTALKNINETFGPSAKKAEVN 611
            .||        |:|..:...:.:.:|....|..:..:|
Zfish   528 VKG--------LIPKKEQCVIFSTDEAASASGTQKLIN 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek4	NP_609615.2	LRR	59..>228	CDD:443914	41/178 (23%)
		leucine-rich repeat	75..99	CDD:275380	3/23 (13%)
		LRR_8	98..158	CDD:404697	17/59 (29%)
		leucine-rich repeat	100..123	CDD:275380	7/22 (32%)
		leucine-rich repeat	124..147	CDD:275380	8/22 (36%)
		leucine-rich repeat	148..171	CDD:275380	3/22 (14%)
		leucine-rich repeat	172..195	CDD:275380	7/22 (32%)
		leucine-rich repeat	196..219	CDD:275380	7/26 (27%)
		LRRCT	228..277	CDD:214507	17/60 (28%)
		IG_like	294..390	CDD:214653	21/96 (22%)
		Ig strand B	296..300	CDD:409353	2/3 (67%)
		Ig strand C	309..323	CDD:409353	1/13 (8%)
		Ig strand E	356..360	CDD:409353	2/3 (67%)
		Ig strand F	370..375	CDD:409353	2/4 (50%)
		Ig strand G	383..386	CDD:409353	0/2 (0%)
lrit1b	NP_001036218.1	LRR	<50..>175	CDD:443914	36/150 (24%)
		leucine-rich repeat	64..84	CDD:275378	6/19 (32%)
		leucine-rich repeat	85..108	CDD:275378	8/22 (36%)
		leucine-rich repeat	109..132	CDD:275378	3/22 (14%)
		leucine-rich repeat	133..156	CDD:275378	7/22 (32%)
		leucine-rich repeat	157..170	CDD:275378	5/12 (42%)
		leucine-rich repeat	185..203	CDD:275378	7/17 (41%)
		LRRCT	199..243	CDD:214507	16/53 (30%)
		Ig	252..343	CDD:472250	25/122 (20%)
		Ig strand B	269..273	CDD:409353	2/3 (67%)
		Ig strand C	282..286	CDD:409353	1/9 (11%)
		Ig strand E	309..313	CDD:409353	2/3 (67%)
		Ig strand F	323..328	CDD:409353	2/4 (50%)
		FN3	459..526	CDD:214495	9/67 (13%)