Protein Alignment kek4 and lrfn1

DIOPT Version :10

• Sequence 1: NP_609615.2
• Gene: kek4 / 34718
• FlyBaseID: FBgn0032484
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_956909.3
• Gene: lrfn1 / 393587
• ZFINID: ZDB-GENE-040426-1227
• Length: 742
• Species: Danio rerio
• Alignment Length: 435
• Identity: 95/435 - (21%)
• Similarity: 157/435 - (36%)
• Gaps: 131/435 - (30%)

  Fly    24 IYCLALIFRSASADWLLDCGNCHCKWNSGKKTADCRNLSLSGVPEYLSPEVQVLDLSHNHIFYLE 88
            ::|: |:| .|.|...|..|.|.|:..|...|..|....|..||..:..:...|.|:.|
Zfish     5 VFCV-LVF-GALAKAQLCPGRCICQTISPTLTLLCAKTGLLFVPPTVDRKTVELRLTDN------ 61

  Fly    89 ENAFLTTHLQNLQKLLIRNGTLKYLNQRSFTQLQILIELDLSNNLLVDLLPNVFDCLSKVRAIFL 153
               |:|.                 :.::.|..:..|:.|.||.|.:..:.|:.|..|..:||:.:
Zfish    62 ---FITA-----------------VRRKDFLNMTSLVHLTLSRNTISQIAPHAFMGLKSLRALHM 106

  Fly   154 NGNLLQA-----------LRHGVFRNLKYLHKIE---------------LKRNRLVSIDAKAFVG 192
            :||.|..           |||.:..| ..:|.||               |..|.|.::..:|...
Zfish   107 DGNRLSVINSDQLKGLMNLRHLILGN-NQIHHIEESSFDEFVATIEDLDLSYNNLRTLPWEAIAR 170

  Fly   193 VPLLSQIYLDNNELTKLRVESFQDLTKLTALSLVE------------------------------ 227
            :..::.:.||:|.:..:.|.:|..||||..|.:..
Zfish   171 MTNINTLTLDHNLIDHIGVGTFTLLTKLVRLDMTSNRLQTLPPDTLFQHAQVLSEPKTSSSSRLT 235

  Fly   228 -----NPWNCTCDLQMFRDFVIGMNLYTPPTSCHYPLQLRGRLWIEDQPEAFACKPKIVYPTLST 287
                 ||.:|.|:|...|......:|.|    |..|..|..:.:...|.|.|.|:|.::     |
Zfish   236 VSFGGNPLHCNCELLWLRRLTREDDLET----CASPEHLMDKYFWSIQEEEFICEPPLI-----T 291

  Fly   288 SINTSK------ENVTLICRVHGSPNTVIAWDYTNQVYESRSKPVKSLQKQRIYIELLREDESKI 346
            ....:|      :.|||.|:..|.|:..|.|.:.:      .|.|.:..:..:|      |...:
Zfish   292 KHQVTKPYVMEGQGVTLKCKAMGDPDPAIHWRFPD------GKLVHNNSRTLLY------DNGTL 344

  Fly   347 RKFGHDVFVSRLTIVNARKSDEGVYTCLAENPGG--KDSVHISVV 389
                 |:.::.|       .|.|.:.|:|.|..|  ..:||:.::
Zfish   345 -----DILITTL-------KDSGAFNCVASNAAGIATAAVHVHMI 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek4	NP_609615.2	LRR	59..>228	CDD:443914	43/229 (19%)
		leucine-rich repeat	75..99	CDD:275380	5/23 (22%)
		LRR_8	98..158	CDD:404697	13/59 (22%)
		leucine-rich repeat	100..123	CDD:275380	1/22 (5%)
		leucine-rich repeat	124..147	CDD:275380	8/22 (36%)
		leucine-rich repeat	148..171	CDD:275380	9/33 (27%)
		leucine-rich repeat	172..195	CDD:275380	7/37 (19%)
		leucine-rich repeat	196..219	CDD:275380	6/22 (27%)
		LRRCT	228..277	CDD:214507	14/48 (29%)
		IG_like	294..390	CDD:214653	22/98 (22%)
		Ig strand B	296..300	CDD:409353	3/3 (100%)
		Ig strand C	309..323	CDD:409353	2/13 (15%)
		Ig strand E	356..360	CDD:409353	1/3 (33%)
		Ig strand F	370..375	CDD:409353	1/4 (25%)
		Ig strand G	383..386	CDD:409353	1/2 (50%)
lrfn1	NP_956909.3	None