DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek4 and Slitrk1

DIOPT Version :9

Sequence 1:NP_001260435.1 Gene:kek4 / 34718 FlyBaseID:FBgn0032484 Length:649 Species:Drosophila melanogaster
Sequence 2:NP_001100753.1 Gene:Slitrk1 / 306147 RGDID:1308858 Length:696 Species:Rattus norvegicus


Alignment Length:312 Identity:73/312 - (23%)
Similarity:116/312 - (37%) Gaps:83/312 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 CHCKWNSGKKTADCRNLSLSGVPEYLSPEVQV--LDLSHNHIFYLEENAF------LTTHLQN-- 99
            |.|....|....||.....:.:..:.:|..|.  |.|..|.:..|..|.|      ::.|::|  
  Rat    29 CSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNG 93

  Fly   100 --------------LQKLLIRNGTLKYLNQRSFTQLQILIELDLSNNLLVDLLPNVFDCLSKVRA 150
                          :::|.|.|..:|...:::|..|..|..|....|||.|:.|..|..|:|:..
  Rat    94 LHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEV 158

  Fly   151 IFLNGNLLQALRHGVFRNLKYLHKIELKRNRLVSIDAKAFVGVPLLSQIYLDNNELTKLRVESFQ 215
            :.||.||:..|...||:.:...| ::|:.|||.::..:                       |..:
  Rat   159 LILNDNLISTLPANVFQYVPITH-LDLRGNRLKTLPYE-----------------------EVLE 199

  Fly   216 DLTKLTALSLVENPWNCTCDLQMFRDFV--IGMNLYTPPTSCHYPLQLRGRLWIED--------- 269
            .:..:..:.|.:|||:|||||...::::  |..|.......|..|.:|:|:...|.         
  Rat   200 QIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPLK 264

  Fly   270 ------------QPEAFACKPKIVYPTLSTSINTSKENVTLICRVHGSPNTV 309
                        |.|.||..|   .|| ...||...|        |.:|..|
  Rat   265 NRVDSSLPAPPAQEETFAPGP---LPT-PFKINGQDE--------HATPGAV 304

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek4NP_001260435.1 leucine-rich repeat 75..99 CDD:275380 8/31 (26%)
LRR_8 99..158 CDD:290566 20/74 (27%)
leucine-rich repeat 100..123 CDD:275380 6/22 (27%)
leucine-rich repeat 124..147 CDD:275380 9/22 (41%)
LRR_8 146..206 CDD:290566 13/59 (22%)
leucine-rich repeat 148..171 CDD:275380 7/22 (32%)
leucine-rich repeat 172..195 CDD:275380 5/22 (23%)
leucine-rich repeat 196..219 CDD:275380 1/22 (5%)
TPKR_C2 228..277 CDD:301599 19/71 (27%)
IG_like 294..390 CDD:214653 4/16 (25%)
Ig 296..387 CDD:143165 3/14 (21%)
Slitrk1NP_001100753.1 leucine-rich repeat 39..60 CDD:275380 3/20 (15%)
leucine-rich repeat 62..83 CDD:275380 6/20 (30%)
leucine-rich repeat 84..107 CDD:275380 2/22 (9%)
LRR_8 108..166 CDD:290566 19/57 (33%)
leucine-rich repeat 108..131 CDD:275380 6/22 (27%)
leucine-rich repeat 132..155 CDD:275380 9/22 (41%)
LRR_8 155..213 CDD:290566 15/81 (19%)
leucine-rich repeat 156..177 CDD:275380 7/20 (35%)
TPKR_C2 212..>250 CDD:301599 13/37 (35%)
leucine-rich repeat 356..372 CDD:275380
leucine-rich repeat 377..400 CDD:275380
leucine-rich repeat 401..424 CDD:275380
LRR_8 425..483 CDD:290566
leucine-rich repeat 425..448 CDD:275380
leucine-rich repeat 449..472 CDD:275380
LRR_8 471..530 CDD:290566
leucine-rich repeat 473..495 CDD:275380
leucine-rich repeat 496..520 CDD:275380
TPKR_C2 529..579 CDD:301599
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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