DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek4 and Gp5

DIOPT Version :9

Sequence 1:NP_001260435.1 Gene:kek4 / 34718 FlyBaseID:FBgn0032484 Length:649 Species:Drosophila melanogaster
Sequence 2:NP_036927.2 Gene:Gp5 / 25259 RGDID:2724 Length:567 Species:Rattus norvegicus


Alignment Length:284 Identity:82/284 - (28%)
Similarity:124/284 - (43%) Gaps:39/284 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    61 LSLSG-VPEYLSPE-------VQVLDLSHNHIFYLEENAFLTTHLQNLQKLLIRNGT-LKYLNQR 116
            |:||| :.|.|.|.       |..|.|..|.:..|.|..|  ..:..|::|.: ||| |:.|...
  Rat   247 LTLSGNLLESLPPALFLHVSCVTRLTLFENPLEELPEVLF--GEMAGLRELWL-NGTHLRTLPAA 308

  Fly   117 SFTQLQILIELDLSNNLLVDLLP-NVFDCLSKVRAIFLNGNLLQALRHGVFRNLKYLHKIELKRN 180
            :|..|..|..|.|:.|.|:..|| .:|..|:::|.:.|:.|.|:.|.....|.|..|.::.|:.|
  Rat   309 AFRNLSGLQTLGLTRNPLLSALPRGMFHGLTELRVLALHTNALEELPEDALRGLGRLRQVSLRHN 373

  Fly   181 RLVSIDAKAFVGVPLLSQIYLDNNELTKLRVESFQDLTKLTALSLVENPWNCTCDLQMFRDF--- 242
            ||.::....|..:..|..:.|::|:|..|..:.|..|.:||.:.|..|||.|.|.|..|..:   
  Rat   374 RLRALPRTLFRNLSSLVTVQLEHNQLKTLPGDVFAALPQLTRVLLGHNPWLCDCGLWPFLQWLRH 438

  Fly   243 ---VIGMNLYTPPTSCHYPLQ---------LRGRLWIEDQPEAFACKP------KIVYPTLSTSI 289
               ::|.:   .|..|:.|..         |:|..|..| |......|      |...||...:.
  Rat   439 HLELLGRD---EPPQCNGPESRASLTFWELLQGDQWCPD-PRGLPPDPPTENALKAPDPTQRPNS 499

  Fly   290 NTSKENVTLICRVHGSPNTVIAWD 313
            :.|...|.|:.|.. ||:....|:
  Rat   500 SQSWAWVQLVARGE-SPDNRFYWN 522

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek4NP_001260435.1 leucine-rich repeat 75..99 CDD:275380 6/23 (26%)
LRR_8 99..158 CDD:290566 21/60 (35%)
leucine-rich repeat 100..123 CDD:275380 9/23 (39%)
leucine-rich repeat 124..147 CDD:275380 9/23 (39%)
LRR_8 146..206 CDD:290566 16/59 (27%)
leucine-rich repeat 148..171 CDD:275380 7/22 (32%)
leucine-rich repeat 172..195 CDD:275380 6/22 (27%)
leucine-rich repeat 196..219 CDD:275380 7/22 (32%)
TPKR_C2 228..277 CDD:301599 16/63 (25%)
IG_like 294..390 CDD:214653 6/20 (30%)
Ig 296..387 CDD:143165 6/18 (33%)
Gp5NP_036927.2 LRR_8 <64..110 CDD:404697
LRR 1 75..96
leucine-rich repeat 76..99 CDD:275380
LRR 2 99..120
leucine-rich repeat 100..123 CDD:275380
PRK15370 <103..>422 CDD:185268 55/177 (31%)
LRR 3 123..144
leucine-rich repeat 124..147 CDD:275380
LRR 4 147..168
leucine-rich repeat 148..171 CDD:275380
LRR 5 171..193
leucine-rich repeat 172..195 CDD:275380
LRR 6 195..216
leucine-rich repeat 196..219 CDD:275380
LRR 7 219..240
leucine-rich repeat 220..243 CDD:275380
LRR 8 243..264 7/16 (44%)
leucine-rich repeat 244..267 CDD:275380 7/19 (37%)
LRR 9 267..288 7/22 (32%)
leucine-rich repeat 268..291 CDD:275380 7/24 (29%)
LRR 10 291..312 8/21 (38%)
leucine-rich repeat 292..315 CDD:275380 9/23 (39%)
LRR 11 315..337 8/21 (38%)
leucine-rich repeat 316..338 CDD:275380 8/21 (38%)
LRR 12 340..361 5/20 (25%)
leucine-rich repeat 341..364 CDD:275380 7/22 (32%)
LRR 13 364..385 6/20 (30%)
leucine-rich repeat 365..388 CDD:275380 6/22 (27%)
LRR 14 388..409 6/20 (30%)
leucine-rich repeat 389..410 CDD:275380 6/20 (30%)
PCC 394..>458 CDD:188093 20/66 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 474..499 6/25 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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