Protein Alignment kek4 and Lrit1

DIOPT Version :10

• Sequence 1: NP_609615.2
• Gene: kek4 / 34718
• FlyBaseID: FBgn0032484
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_666357.2
• Gene: Lrit1 / 239037
• MGIID: 2385320
• Length: 624
• Species: Mus musculus
• Alignment Length: 386
• Identity: 86/386 - (22%)
• Similarity: 135/386 - (34%)
• Gaps: 81/386 - (20%)

  Fly    38 WLLDCGNCHCKW----------------NSGKKTADCRNLSLSGVPEYLSPEVQVLDLSHNHIFY 86
            |||..|..|..|                .|..:|..|.:..|:..|..:.|:.
Mouse     9 WLLALGGPHQAWGFCPSECSCSLRILSDGSKARTVVCSDPDLTLPPASIPPDT------------ 61

  Fly    87 LEENAFLTTHLQNLQKLLIRNGTLKYLNQRSFTQLQILIELDLSNNLLVDLLPNVFDCLSKVRAI 151
                          .||.:....::.:...:|..|..|.:|.|..|.|.:|...:...|.::|.:
Mouse    62 --------------CKLRLERTAIRRVPGETFRPLSRLEQLWLPYNALSELSALMLRGLRRLREL 112

  Fly   152 FLNGNLLQALRHGVFRNLKYLHKIELKRNRLVSIDAKAFVGVPLLSQIYLDNNELTKLRVESFQD 216
            .|.||.|........|:...|..::|:.|||.::..:|...:..|:.:.|.||:|.:|..|....
Mouse   113 RLPGNRLVTFPWAALRDTPQLQLLDLQANRLSTLPPEAAHFLENLTFLDLSNNQLMRLPEELLDV 177

  Fly   217 LTKLTA------------LSLVENPWNCTC---DLQMFRDFVIGMNL--YTPPTSCHYPLQLRGR 264
            ...|..            |.|.:|||.|.|   ||....|..:..||  ......|..|..|.|.
Mouse   178 WAHLKTGPFLSGHHARLILGLQDNPWVCDCRLYDLVHLLDGWVSSNLIFIEARLRCASPRSLAGV 242

  Fly   265 LWIEDQPEAFACKPKIVYPTLSTSINTSKENVTLICRVHGSPNTVIAWDYTNQVYESRSKPVKSL 329
            .:  .|.|...|:...:.|.:::.|:.....|.|.|...|.|...::|...|      .:|:...
Mouse   243 AF--SQLELRKCQSPELRPGVTSIISPLGSTVLLRCGATGIPGPEMSWRRAN------GRPLNGT 299

  Fly   330 QKQRIYIELLREDESKIRKFGHDVFVSRLTIVNARKSDEGVYTCLAENPGGKDSVHISVVV 390
            ..|.:..:            |....:..|.:|:.  .|.|.|.|.|:|..|.....||::|
Mouse   300 VHQEVSSD------------GSSWTLLDLPVVSL--FDSGDYICQAKNFLGASETLISLIV 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek4	NP_609615.2	LRR	59..>228	CDD:443914	36/180 (20%)
		leucine-rich repeat	75..99	CDD:275380	0/23 (0%)
		LRR_8	98..158	CDD:404697	15/59 (25%)
		leucine-rich repeat	100..123	CDD:275380	4/22 (18%)
		leucine-rich repeat	124..147	CDD:275380	7/22 (32%)
		leucine-rich repeat	148..171	CDD:275380	6/22 (27%)
		leucine-rich repeat	172..195	CDD:275380	6/22 (27%)
		leucine-rich repeat	196..219	CDD:275380	7/22 (32%)
		LRRCT	228..277	CDD:214507	16/53 (30%)
		IG_like	294..390	CDD:214653	21/95 (22%)
		Ig strand B	296..300	CDD:409353	2/3 (67%)
		Ig strand C	309..323	CDD:409353	2/13 (15%)
		Ig strand E	356..360	CDD:409353	1/3 (33%)
		Ig strand F	370..375	CDD:409353	2/4 (50%)
		Ig strand G	383..386	CDD:409353	0/2 (0%)
Lrit1	NP_666357.2	LRRNT	23..61	CDD:214470	6/37 (16%)
		LRR 1	60..81		3/46 (7%)
		LRR	<63..>174	CDD:443914	29/110 (26%)
		leucine-rich repeat	64..84	CDD:275378	3/19 (16%)
		LRR 2	84..105		6/20 (30%)
		leucine-rich repeat	85..132	CDD:275378	13/46 (28%)
		LRR 3	108..129		5/20 (25%)
		LRR 4	132..153		6/20 (30%)
		leucine-rich repeat	133..156	CDD:275378	6/22 (27%)
		LRR 5	156..177		7/20 (35%)
		leucine-rich repeat	157..180	CDD:275378	7/22 (32%)
		leucine-rich repeat	181..205	CDD:275378	6/23 (26%)
		LRRCT	201..>241	CDD:214507	13/39 (33%)
		Ig	258..346	CDD:472250	23/107 (21%)
		Ig strand B	272..276	CDD:409353	2/3 (67%)
		Ig strand C	285..289	CDD:409353	0/3 (0%)
		Ig strand E	309..313	CDD:409353	0/3 (0%)
		Ig strand F	326..331	CDD:409353	2/4 (50%)
		Ig strand G	339..342	CDD:409353	0/2 (0%)
		FN3	432..502	CDD:214495
		LRR 6	526..549