Protein Alignment kek4 and iglr-3

DIOPT Version :9

• Sequence 1: NP_001260435.1
• Gene: kek4 / 34718
• FlyBaseID: FBgn0032484
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001293349.1
• Gene: iglr-3 / 171771
• WormBaseID: WBGene00021353
• Length: 488
• Species: Caenorhabditis elegans
• Alignment Length: 408
• Identity: 95/408 - (23%)
• Similarity: 157/408 - (38%)
• Gaps: 73/408 - (17%)

  Fly    39 LLDCGN----CHCKWNSGKKTADCRNLSLSGVPEYLSPEVQVLDLSHNHIFYLEENAFLTTHLQN 99
            ::.|.|    |...|.|.:.:.||.:|:|...|:.| |.|..|.||:|.||.:   ....:..:.
 Worm    13 IISCSNAPKTCKSFWISNRPSQDCASLTLQEPPQLL-PNVLSLSLSNNSIFRI---TTFPSEYRR 73

  Fly   100 LQKLLIRNGTLKYLNQRSFTQLQILIELDLSNNLLVDL-LPNVFDCLSKVRAIFLNGNLLQALRH 163
            ||.|.:....|:.|:..:.:..:.|.|||:|.|.|..| :|.....|..:...|.....:..:.|
 Worm    74 LQSLRLDQCQLEKLDFDALSVFEQLRELDVSRNSLSKLIIPRNLASLRVLNLAFNAFTYVPDMSH 138

  Fly   164 GVFRNLKYLHKIELKRNRLVSIDAKAFVGVPLLSQIYLDNNELTKLRVESFQDLT------KLTA 222
                 |:.|..::|..|||:|:..:.   :|.       |.|:.:|....||.|:      ||..
 Worm   139 -----LESLRLVDLSHNRLISVRPRM---LPF-------NLEVVRLAANRFQHLSPWPFLHKLQE 188

  Fly   223 LSLVENPWNCTCDLQMFRDFVIGMNLY-TPPTSCHYPLQLR-----GRLWIEDQPEAFACKPKIV 281
            |.:..|...|.|.|..|..:...:.|: :....|..|.:||     |:.         .|.|.:|
 Worm   189 LDVTFNDLECDCSLWHFVTWAEKLALFDSTMLPCRRPSELRKSPIDGKT---------VCGPTVV 244

  Fly   282 YPTLSTSINTSKENVTLICRVHGSPNTVIAWDYTNQVYESRSKPVKSLQKQRIYIELLREDESKI 346
            ..:..:::.:..:...:.|....:|:..:.|.:..:...|      .|.::.:       .||..
 Worm   245 TSSPESAVVSLDDAHVMCCTALATPSPQLYWQFNGKNISS------GLSQKHL-------SESGK 296

  Fly   347 RKFGHDVFVSRLTIVNARKSDEGVYTCLAENPGGKDSVHISVVVQKDMERISLIDSNFFAIVCLI 411
            .:|       .|.|...|..|.|.|.|:|...|...|....  |::|...|.|..:....|.|..
 Worm   297 LEF-------CLEIPKVRLKDMGKYKCVASLAGLNSSKEFH--VERDKIPIVLNSAEGIMIYCQF 352

  Fly   412 AMGFLSMSILFSLVTCLI 429
            .:      ..|..|.|:|
 Worm   353 TI------CTFIGVCCVI 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek4	NP_001260435.1	leucine-rich repeat	75..99	CDD:275380	6/23 (26%)
		LRR_8	99..158	CDD:290566	16/59 (27%)
		leucine-rich repeat	100..123	CDD:275380	5/22 (23%)
		leucine-rich repeat	124..147	CDD:275380	10/23 (43%)
		LRR_8	146..206	CDD:290566	11/59 (19%)
		leucine-rich repeat	148..171	CDD:275380	3/22 (14%)
		leucine-rich repeat	172..195	CDD:275380	6/22 (27%)
		leucine-rich repeat	196..219	CDD:275380	6/28 (21%)
		TPKR_C2	228..277	CDD:301599	11/54 (20%)
		IG_like	294..390	CDD:214653	18/95 (19%)
		Ig	296..387	CDD:143165	18/90 (20%)
iglr-3	NP_001293349.1	LRR	<47..>196	CDD:227223	44/167 (26%)
		leucine-rich repeat	51..73	CDD:275380	7/24 (29%)
		leucine-rich repeat	74..97	CDD:275380	5/22 (23%)
		leucine-rich repeat	98..119	CDD:275380	9/20 (45%)
		leucine-rich repeat	120..141	CDD:275380	4/25 (16%)
		leucine-rich repeat	142..163	CDD:275380	7/30 (23%)
		leucine-rich repeat	164..185	CDD:275380	5/20 (25%)
		Ig_3	243..319	CDD:372822	16/95 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	66	1.000	Inparanoid score	I3947
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.920