Protein Alignment kek4 and kek2

DIOPT Version :10

• Sequence 1: NP_609615.2
• Gene: kek4 / 34718
• FlyBaseID: FBgn0032484
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_061512480.1
• Gene: kek2 / 1280097
• VectorBaseID: AGAMI1_010202
• Length: 877
• Species: Anopheles gambiae
• Alignment Length: 590
• Identity: 157/590 - (26%)
• Similarity: 259/590 - (43%)
• Gaps: 93/590 - (15%)

  Fly    28 ALIFRSASADW-----LLDCGN--CHCKWNSGKKTADCRNLSLSGVPEYLSPEVQVLDLSHNHIF 85
            ||:..:.:..|     ...|..  |.|||..||:|.:|....|:.:|:.:.|..|||:.|.|.:.
Mosquito     9 ALVLLALTVSWSALPPATGCPAEVCVCKWKGGKQTVECGGRFLNRLPDGMDPGTQVLNFSGNSLT 73

  Fly    86 YLEENAFLTTHLQNLQKLLIRNGTLKYLNQRSFTQLQILIELDLSNNLLVDLLPNVFDCLSKVRA 150
            .|:...|....|.||||:.:....|..::.|:|..|..|:|||||:|.|.::....|...:.:..
Mosquito    74 ILQSERFRKMELINLQKIYLARNQLVKIHDRAFRGLTNLVELDLSDNTLSEVPTETFQDYAALMR 138

  Fly   151 IFLNGNLLQALRHGVFRNLKYLHKIELKRNRLVSIDAKAFVGVPLLSQIYLDNNELTKLR----- 210
            :.|:||.::|||...|:.|.||..:||...::..::.:||:|:..|..:.||.|.:..:|
Mosquito   139 LSLSGNPIRALRASAFKQLSYLTTLELSNCQIELVEDEAFIGMDNLEWLRLDGNRIATIRGAHVL 203

  Fly   211 VESFQDLTKLTALSLVENPWNCTCDLQMFRDFVIGMNLYTPP----TSCHYPLQLRGR----LWI 267
            .||      |..::|..|.|:|.|.|   .|....:|.:..|    ..|..|.:|.|.    |.:
Mosquito   204 PES------LHGINLQSNRWHCDCHL---TDVYTWLNSFNVPQREEIKCSGPARLAGETVKTLTL 259

  Fly   268 EDQPEAFACKPKIVYPTLSTSINTSKENVTLICRVHGSPNTVIAWDYTNQVYESRSKPVKSLQKQ 332
            :|    .||.| :|.|..|........|::|.||:..:|...:||.:..||..:.|....:|...
Mosquito   260 DD----LACLP-VVTPETSYREIAEGRNISLDCRIVATPEPTVAWLFQGQVLLNDSFLSPNLHLY 319

  Fly   333 RIYIELLREDESKIRKFGHDVFVSRLTIVNARKSDEGVYTCLAENPGGK----DSVHISVVVQKD 393
            ....||   |.:|     |    |.|.|.|....|.|.|:|:|||..|:    .::|:.|..:..
Mosquito   320 YFVDEL---DGAK-----H----SELFIYNINADDNGTYSCVAENSAGRVQTNYTLHVIVKEEPV 372

  Fly   394 MERISLIDSNFFAIVCLIAMGFLSMSILFSLVTCLIFKRFKQFHPGQHTYLQPTSLPVQSP-GSE 457
            :|:::..:..|.|||...|...:.:::|..:|.|...:..:....|           .:.| |::
Mosquito   373 VEQVTFSEEYFLAIVAASAATAVLLALLCCIVACKCARARRASGSG-----------AKKPRGAK 426

  Fly   458 EATA--ISALSSGVIRESKIVLD---PLSA--------INEPSN-KNYTLFKTSNSNGSEYMHTR 508
            .|||  :..:.:|..:.:.|..|   ||:|        :.:.|| ::..|:..:|.||.:
Mosquito   427 GATADGLVGVPAGQQKCASITHDLGEPLTAGKLNGALGLGDGSNPQDIVLYLNANPNGLD----- 486

  Fly   509 NYKDVRLNSNTYTENLDN--QAESISSRNRELYSNIAGDREKEELKQKDELDKD------SRQSS 565
               ...||:.|......:  .|.|...:|.:|.::....:.|.. .:.|.:|.|      ..|||
Mosquito   487 ---KAALNNMTAMAQFCSPPSARSYQDQNPDLINDAESGQHKAR-PRPDAIDSDLGEKDSDEQSS 547

  Fly   566 LQSTG 570
            :|..|
Mosquito   548 VQDGG 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek4	NP_609615.2	LRR	59..>228	CDD:443914	52/173 (30%)
		leucine-rich repeat	75..99	CDD:275380	8/23 (35%)
		LRR_8	98..158	CDD:404697	20/59 (34%)
		leucine-rich repeat	100..123	CDD:275380	7/22 (32%)
		leucine-rich repeat	124..147	CDD:275380	9/22 (41%)
		leucine-rich repeat	148..171	CDD:275380	8/22 (36%)
		leucine-rich repeat	172..195	CDD:275380	6/22 (27%)
		leucine-rich repeat	196..219	CDD:275380	7/27 (26%)
		LRRCT	228..277	CDD:214507	15/56 (27%)
		IG_like	294..390	CDD:214653	30/99 (30%)
		Ig strand B	296..300	CDD:409353	1/3 (33%)
		Ig strand C	309..323	CDD:409353	4/13 (31%)
		Ig strand E	356..360	CDD:409353	2/3 (67%)
		Ig strand F	370..375	CDD:409353	2/4 (50%)
		Ig strand G	383..386	CDD:409353	0/2 (0%)
kek2	XP_061512480.1	None