Protein Alignment kek4 and LOC1271792

DIOPT Version :10

• Sequence 1: NP_609615.2
• Gene: kek4 / 34718
• FlyBaseID: FBgn0032484
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_310646.5
• Gene: LOC1271792 / 1271792
• VectorBaseID: AGAMI1_000422
• Length: 805
• Species: Anopheles gambiae
• Alignment Length: 508
• Identity: 152/508 - (29%)
• Similarity: 230/508 - (45%)
• Gaps: 52/508 - (10%)

  Fly    19 LFLFKIYC--LALIFRSA-SADWLLDC-GNCHCKWNSGKKTADCRNLSLSGVPEYLSPEVQVLDL 79
            |.:.::||  |.|:..:| .|||...| .||.|||::|||:|.|....||.||..||.|:|||.|
Mosquito    10 LKMIQLYCTVLFLLLSTALCADWSASCPQNCTCKWSNGKKSALCNGADLSAVPSNLSTEIQVLVL 74

  Fly    80 SHNHIFYLEENAFLTTHLQNLQKLLIRNGTLKYLNQRSFTQLQILIELDLSNNLLVDLLPNVFDC 144
            :.|:|.||....|.|..|.||||:.:::..:|||::.:|..|:||:|:|||.|.:..|....|..
Mosquito    75 NDNNIPYLNREEFTTLGLVNLQKIHLKHSRVKYLHREAFKNLKILVEVDLSENEIETLDKQTFAG 139

  Fly   145 LSKVRAIFLNGNLLQALRHGVFRNLKYLHKIELKRNRLVSIDAKAFVGVPLLSQIYLDNNELTKL 209
            .:::|.|.|..|.::.|....|..|.||..|:|...:|..:...||..:.||..:.|..|.|..|
Mosquito   140 NNRLRIINLYDNPIKMLVAEQFPVLPYLRNIDLHGCQLRYVAETAFSNLDLLEFLDLSKNRLESL 204

  Fly   210 RVESFQDLTKLTALSLVENPWNCTCDLQMFRDFVIGMNLYTPPTSCHYPLQLRGRLWIEDQPEAF 274
            ....|..:..|..|.|.||.|||.|.|:.||::.:..:|......|..|..|:|..|...:.|.|
Mosquito   205 PHHVFNHMKNLKTLILEENWWNCDCHLRDFRNWYLNSSLNRRSLICQRPYALKGLSWEYLETEQF 269

  Fly   275 ACKPKIVYPTLSTSINTSKENVTLICRVHGSPNTVIAWDYTNQVYESRSKPVKSLQKQRIYIELL 339
            .|.|.:........|.....|:|..|.|.|.|...:.||...          |.:.:....|
Mosquito   270 GCMPTVEIYRDEYEIEDLGTNITYKCAVSGDPEPNVRWDMNG----------KDVDQDNAII--- 321

  Fly   340 REDESKIRKFGHDVFVSRLTIVNARKSDEGVYTCLAENPGGKDSVHISVVVQKDMERISLIDSNF 404
             |.|..:...|.....|.|||:|...:|.|.|||.|:|..|..|.:.|:|:.:.:||:.:.....
Mosquito   322 -ETERHVAFDGSVTLWSNLTILNVTNNDSGFYTCTAQNRIGLASKNFSLVLPEVVERVIIKTPET 385

  Fly   405 FAIVCLI------AMGFLSMSILFSLVTCLIFKRFK------------QFHPGQHTYLQPTSLPV 451
            |....||      ..|.|::|:    |.||:.::.:            .|:..:...|   .|.:
Mosquito   386 FWYFGLILGIFGTIFGLLALSV----VVCLVKRKLRMRRRRKTIKNSVSFNDQEKKLL---DLSI 443

  Fly   452 QSPGSEEATAISALSSGVIRESKIVLDPLSAINEPSNKNYTLFKTSNSNGSEY 504
            .:...:|.:|...::.....:|.|.::|:         ..|:...:.|...||
Mosquito   444 TTNERQEFSASDVVTPSTKTDSTIAMEPV---------QITIESIATSKREEY 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek4	NP_609615.2	LRR	59..>228	CDD:443914	60/168 (36%)
		leucine-rich repeat	75..99	CDD:275380	11/23 (48%)
		LRR_8	98..158	CDD:404697	22/59 (37%)
		leucine-rich repeat	100..123	CDD:275380	8/22 (36%)
		leucine-rich repeat	124..147	CDD:275380	8/22 (36%)
		leucine-rich repeat	148..171	CDD:275380	7/22 (32%)
		leucine-rich repeat	172..195	CDD:275380	6/22 (27%)
		leucine-rich repeat	196..219	CDD:275380	6/22 (27%)
		LRRCT	228..277	CDD:214507	16/48 (33%)
		IG_like	294..390	CDD:214653	28/95 (29%)
		Ig strand B	296..300	CDD:409353	1/3 (33%)
		Ig strand C	309..323	CDD:409353	2/13 (15%)
		Ig strand E	356..360	CDD:409353	2/3 (67%)
		Ig strand F	370..375	CDD:409353	3/4 (75%)
		Ig strand G	383..386	CDD:409353	1/2 (50%)
LOC1271792	XP_310646.5	LRR	<67..>224	CDD:443914	55/156 (35%)
		leucine-rich repeat	69..94	CDD:275380	11/24 (46%)
		leucine-rich repeat	95..118	CDD:275380	8/22 (36%)
		leucine-rich repeat	119..142	CDD:275380	8/22 (36%)
		leucine-rich repeat	143..166	CDD:275380	7/22 (32%)
		leucine-rich repeat	167..190	CDD:275380	6/22 (27%)
		leucine-rich repeat	191..214	CDD:275380	6/22 (27%)
		LRRCT	223..271	CDD:214507	16/47 (34%)
		Ig	286..370	CDD:472250	28/97 (29%)
		Ig strand B	291..295	CDD:409353	1/3 (33%)
		Ig strand C	304..308	CDD:409353	0/3 (0%)
		Ig strand E	326..341	CDD:409353	3/14 (21%)
		Ig strand F	351..356	CDD:409353	3/4 (75%)
		Ig strand G	364..367	CDD:409353	1/2 (50%)