DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek4 and lrrn3a

DIOPT Version :9

Sequence 1:NP_001260435.1 Gene:kek4 / 34718 FlyBaseID:FBgn0032484 Length:649 Species:Drosophila melanogaster
Sequence 2:XP_005163128.1 Gene:lrrn3a / 101887059 ZFINID:ZDB-GENE-061220-7 Length:691 Species:Danio rerio


Alignment Length:529 Identity:116/529 - (21%)
Similarity:172/529 - (32%) Gaps:194/529 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 LALIFRSASADWLLDCGN-CHCK---WNS------GKKTADCRNLSLSGVPEYLSPEVQVL---- 77
            |||.....::.|.:.|.. |.|:   |.|      ...|.||.:|.|..:||.|..:.|||    
Zfish    14 LALTNSVQASKWSVVCLKLCKCEIRPWFSPLSMYNEAPTVDCNDLGLLTLPERLPSDTQVLLSQA 78

  Fly    78 -------------------DLSHNHI----------------FYLEEN-------AFLTTHLQNL 100
                               |||.|:|                .:||||       .|| .|..||
Zfish    79 NSIAKIDSPLDYLVNLTEVDLSRNNISSLSDIYIGHIPQLLSLHLEENWLSSLHDNFL-AHFPNL 142

  Fly   101 QKLLIRNGTLKYLNQRSFTQLQILIELDLSNNLLVDLLPNVFDCLSKVRAIFLNGNLLQALRHGV 165
            |:|.:.:..|..::..:|..|..|:.|.|::|.|..:....|..||::..:.:..|.:..:::..
Zfish   143 QELYVNHNLLSLISAEAFQGLNKLLRLHLNSNQLRAIRSEWFQDLSQLEILMIGENPIARIQNMN 207

  Fly   166 F---------------------------------------------------RNLKYL------- 172
            |                                                   ||||:|       
Zfish   208 FKPLINLRSLVLTRMNLTEIPDSALVGLDKLESVSFYDNMFPKVPQAALRQVRNLKFLDLNKNPI 272

  Fly   173 ------------HKIELKRN---RLVSIDA-------------------------KAFVGVPLLS 197
                        |..||..|   .|||||:                         .||..:|.|.
Zfish   273 ERIQRGDFVDMIHLKELGINSMPELVSIDSFALHNLPELTKIEATNNPRLSYIHPNAFSQLPRLE 337

  Fly   198 QIYLDNNELTKLRVESFQDLTKLTALSLVENPWNCTCDLQMFRDFVIGMN------LYTPPTSCH 256
            .:.|::|.|..|...:.:.|..|..:|:..||..|.|.::.     |.||      :......|.
Zfish   338 SLMLNSNALRALHHITVESLPNLQEVSIHSNPIYCDCVIRW-----INMNNTRVRFMELDALLCA 397

  Fly   257 YPLQLRGRL--WIEDQPEAFACKPKIVYPTLSTSINTSKEN-VTLICRVHGSPNTVIAWDYTNQV 318
            .|.:..|||  .:..:..|..|.|.|...:|...:|....: |:|.||....|...|.|     |
Zfish   398 GPSEFEGRLVKQVHSREMADICLPLISPESLPDQVNVGTGHLVSLHCRAFADPEPEIYW-----V 457

  Fly   319 YESRSK--PVKSLQKQRIYIELLREDESKIRKFGHDVFVSRLTIVNARKSDEGVYTCLAENPGGK 381
            ..|..|  |....:|..::.|                  ....|....:::.|.|||:|.|..|.
Zfish   458 TPSGEKILPQMDSKKYHLHPE------------------GTFDIYGITENEAGQYTCVAHNLIGV 504

  Fly   382 DSVHISVVV 390
            |...:.|:|
Zfish   505 DMRSVLVIV 513

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek4NP_001260435.1 leucine-rich repeat 75..99 CDD:275380 15/69 (22%)
LRR_8 99..158 CDD:290566 16/58 (28%)
leucine-rich repeat 100..123 CDD:275380 6/22 (27%)
leucine-rich repeat 124..147 CDD:275380 7/22 (32%)
LRR_8 146..206 CDD:290566 23/157 (15%)
leucine-rich repeat 148..171 CDD:275380 5/73 (7%)
leucine-rich repeat 172..195 CDD:275380 12/69 (17%)
leucine-rich repeat 196..219 CDD:275380 6/22 (27%)
TPKR_C2 228..277 CDD:301599 13/56 (23%)
IG_like 294..390 CDD:214653 23/98 (23%)
Ig 296..387 CDD:143165 22/92 (24%)
lrrn3aXP_005163128.1 LRR_RI 29..>272 CDD:238064 50/243 (21%)
leucine-rich repeat 52..70 CDD:275380 8/17 (47%)
leucine-rich repeat 71..93 CDD:275380 3/21 (14%)
leucine-rich repeat 94..117 CDD:275380 5/22 (23%)
leucine-rich repeat 118..141 CDD:275380 7/23 (30%)
LRR_8 140..200 CDD:290566 16/59 (27%)
leucine-rich repeat 142..165 CDD:275380 6/22 (27%)
leucine-rich repeat 166..189 CDD:275380 7/22 (32%)
leucine-rich repeat 190..213 CDD:275380 2/22 (9%)
LRR_8 213..272 CDD:290566 5/58 (9%)
leucine-rich repeat 214..237 CDD:275380 0/22 (0%)
leucine-rich repeat 238..261 CDD:275380 0/22 (0%)
leucine-rich repeat 262..285 CDD:275380 3/22 (14%)
leucine-rich repeat 286..310 CDD:275380 8/23 (35%)
LRR_8 309..370 CDD:290566 12/60 (20%)
leucine-rich repeat 311..333 CDD:275380 2/21 (10%)
leucine-rich repeat 336..359 CDD:275378 6/22 (27%)
leucine-rich repeat 360..372 CDD:275378 4/11 (36%)
LRRCT 368..412 CDD:214507 12/48 (25%)
IG_like 429..513 CDD:214653 24/106 (23%)
Ig 437..513 CDD:299845 23/98 (23%)
FN3 526..>591 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm6470
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.000

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