Protein Alignment kek4 and si:ch211-170a17.1

DIOPT Version :10

• Sequence 1: NP_609615.2
• Gene: kek4 / 34718
• FlyBaseID: FBgn0032484
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_021336930.1
• Gene: si:ch211-170a17.1 / 101884914
• ZFINID: ZDB-LINCRNAG-131127-306
• Length: 628
• Species: Danio rerio
• Alignment Length: 522
• Identity: 127/522 - (24%)
• Similarity: 183/522 - (35%)
• Gaps: 149/522 - (28%)

  Fly    13 SLKHLSLFLFKIYCLAL-IFRSASADWLLDCGNCHCKWNSGKKTA--------DCRNLSLSGVPE 68
            ||..|||...:|..|:| :|...|....||.        |..|..        |.|||
Zfish   127 SLHSLSLKSNRIKLLSLGVFTGLSNLTNLDI--------SDNKVVILVDYMFQDLRNL------- 176

  Fly    69 YLSPEVQVLDLSHNHIFYLEENAF---------------LT-------THLQNLQKLLIRNGTLK 111
                  :.||:..|.:.|:...||               ||       :||.||..|.:|..|:.
Zfish   177 ------RSLDVGDNELVYISHRAFSGLLSLESLTLERCNLTVVPTDALSHLHNLVSLHMRYLTIS 235

  Fly   112 YLNQRSFTQLQILIELDLSNNLLVDLLP-NVFDCLSKVRAIFLNGNL----LQALRH-------- 163
            .|:..||.:|..|..|::.|...:|:.| |....|:.......|.||    .|||.|
Zfish   236 TLHPYSFKKLFHLRHLEIDNWPSLDVFPANSLHGLNLTTLSVTNTNLSTFPYQALHHLPYLTHLN 300

  Fly   164 -----------GVFRNLKYLHKIELKRNRLVSIDAKAFVGVPLLSQIYLDNNELTKLRVESFQDL 217
                       |:.:||..|.::.|..:.||||:..||.|:..|..:.:.:|.|..|...:|...
Zfish   301 LSYSRIRTVEGGLLQNLVRLRELRLAGSHLVSIEPYAFQGIRWLRLLNISHNRLDTLEKGAFHAP 365

  Fly   218 TKLTALSLVENPWNCTCDLQ--MFRDFVIGMNLYTPPTSCHYPLQLRGRLWIEDQPEAF------ 274
            ..|..|.:..||..|.|.|.  :.|...|......|..|.....|.|       |.:.|
Zfish   366 EALQVLLINNNPLVCDCRLMWLLQRHHSISFGDTQPECSSPEGSQRR-------QSKEFKEALLS 423

  Fly   275 ---AC-KPKI-VYPTLSTSINTSKENVTLICRVHGSPNTVIAWDYTNQVYESRSKPVKSLQKQRI 334
               .| |||| ...|.|.|:... ::..|.|...|:|...|:|          ..|.|
Zfish   424 NYVTCTKPKIRRNRTQSVSVEEG-QSAHLNCTAEGTPRPTISW----------VSPRK------- 470

  Fly   335 YIELLREDESKIRKFGHDVFVSRLTIVNARKSDEGVYTCLAENPGGKDSVHISVVVQK------- 392
             ::|...:..::....:    ..|.|......|.|||.|.|.|..|.|::.:|:.|:.
Zfish   471 -VQLNNRNHGRVMVHNN----GSLDIKAVEVQDGGVYVCTASNSAGNDTLMVSLSVKSLGSLYAN 530

  Fly   393 ------DMERISLIDSN---------FFAIVCLIAMG---FLSMSILFSLVTCLIFKRFKQFHPG 439
                  |....:...:|         ...|:...|||   ||.: :||..:...::.|.|    |
Zfish   531 RTQHYTDTSNATANGTNLPNVTFGLDLKTILVSTAMGCFTFLGV-VLFCFLLLFVWSRGK----G 590

  Fly   440 QH 441
            :|
Zfish   591 KH 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek4	NP_609615.2	LRR	59..>228	CDD:443914	55/214 (26%)
		leucine-rich repeat	75..99	CDD:275380	10/45 (22%)
		LRR_8	98..158	CDD:404697	19/64 (30%)
		leucine-rich repeat	100..123	CDD:275380	8/22 (36%)
		leucine-rich repeat	124..147	CDD:275380	7/23 (30%)
		leucine-rich repeat	148..171	CDD:275380	10/45 (22%)
		leucine-rich repeat	172..195	CDD:275380	9/22 (41%)
		leucine-rich repeat	196..219	CDD:275380	5/22 (23%)
		LRRCT	228..277	CDD:214507	14/60 (23%)
		IG_like	294..390	CDD:214653	21/95 (22%)
		Ig strand B	296..300	CDD:409353	1/3 (33%)
		Ig strand C	309..323	CDD:409353	2/13 (15%)
		Ig strand E	356..360	CDD:409353	1/3 (33%)
		Ig strand F	370..375	CDD:409353	3/4 (75%)
		Ig strand G	383..386	CDD:409353	0/2 (0%)
si:ch211-170a17.1	XP_021336930.1	LRR	69..>378	CDD:443914	71/271 (26%)
		leucine-rich repeat	80..103	CDD:275380
		leucine-rich repeat	104..127	CDD:275380	127/522 (24%)
		leucine-rich repeat	128..151	CDD:275380	8/22 (36%)
		leucine-rich repeat	152..175	CDD:275380	5/30 (17%)
		leucine-rich repeat	176..223	CDD:275380	11/59 (19%)
		leucine-rich repeat	224..247	CDD:275380	8/22 (36%)
		leucine-rich repeat	248..295	CDD:275380	14/46 (30%)
		leucine-rich repeat	296..319	CDD:275380	3/22 (14%)
		leucine-rich repeat	320..343	CDD:275380	9/22 (41%)
		leucine-rich repeat	344..363	CDD:275380	4/18 (22%)
		PCC	348..>430	CDD:188093	20/88 (23%)
		Ig_3	430..508	CDD:464046	24/100 (24%)