DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek4 and lrfn2

DIOPT Version :9

Sequence 1:NP_001260435.1 Gene:kek4 / 34718 FlyBaseID:FBgn0032484 Length:649 Species:Drosophila melanogaster
Sequence 2:XP_031758515.1 Gene:lrfn2 / 100491687 XenbaseID:XB-GENE-6035533 Length:765 Species:Xenopus tropicalis


Alignment Length:416 Identity:95/416 - (22%)
Similarity:152/416 - (36%) Gaps:91/416 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 KIYCLALIFRSASADWLLDCGNCHCKWNSGKKTADCRNLS-----------LSGVPEYLSPEVQV 76
            ||.|..|:|..|            ...||..|...|:|||           |..||..:......
 Frog     3 KILCSLLVFGMA------------VMVNSCPKYCVCQNLSESLGTLCPTKGLLFVPMDIDRRTVE 55

  Fly    77 LDLSHNHIFYLEENAFLTTHLQNLQKLLIRNGTLKYLNQRSFTQLQILIELDLSNNLLVDLLPNV 141
            |.|..|.|..:....|  .::..|..|.:...|:.|:...||..|:.|..|.|.:|.|.:|..:|
 Frog    56 LRLGGNFIISINRQDF--ANMTGLVDLTLSRNTISYIQPYSFIDLESLRSLHLDSNRLTNLGDDV 118

  Fly   142 FDCLSKVRAIFLNGNLLQALRHGVFRN-LKYLHKIELKRNRLVSIDAKAFVGVPLLSQIYLDNNE 205
            |..|..::.:.:|.|.|.::....|.: |:.|..::|..|.|.::...|...:..|.|:.||:|.
 Frog   119 FRGLINLQHLIMNNNQLNSIAEDAFEDLLQTLEDLDLSYNNLKTVPWDAVRRMVNLHQLSLDHNL 183

  Fly   206 LTKLRVESFQDLTKLTALSLVE-----------------------------------NPWNCTCD 235
            :..:...:||||.||..|.|..                                   ||.:|.|:
 Frog   184 IYYITEGTFQDLNKLARLDLTSNRLQKLPPDPIFARSQISMTSATPFSPPLSLSFGGNPLHCNCE 248

  Fly   236 LQMFRDFVIGMNLYTPPTSCHYPLQLRGRLWIEDQPEAFACKPKIVYPTLSTSINTSKENVTLIC 300
            |...|    .::......:|..|..|:||.:...:.|.|.|:|.::.......:....:..:|.|
 Frog   249 LLWLR----RLDREDDMETCASPSALKGRYFWYVREEEFVCEPPLITQYTQRLLVLEGQTASLKC 309

  Fly   301 RVHGSPNTVIAWDYTNQVYESRSKPVKSLQKQRIYIELLREDESKIRKFGHDVFVSRLTIVNARK 365
            :..|.|..||.|      .....:.:.:..:..:|..                  ..|.|:....
 Frog   310 KAVGDPLPVIHW------VAPDGRLIGNSSRTTVYDN------------------GTLDILITTS 350

  Fly   366 SDEGVYTCLAENPGGK--DSVHISVV 389
            .|.|.:||:|.|..|:  ..|.:|:|
 Frog   351 KDYGTFTCIAANAAGELTAPVELSIV 376

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek4NP_001260435.1 leucine-rich repeat 75..99 CDD:275380 5/23 (22%)
LRR_8 99..158 CDD:290566 18/58 (31%)
leucine-rich repeat 100..123 CDD:275380 7/22 (32%)
leucine-rich repeat 124..147 CDD:275380 9/22 (41%)
LRR_8 146..206 CDD:290566 15/60 (25%)
leucine-rich repeat 148..171 CDD:275380 5/23 (22%)
leucine-rich repeat 172..195 CDD:275380 5/22 (23%)
leucine-rich repeat 196..219 CDD:275380 9/22 (41%)
TPKR_C2 228..277 CDD:301599 13/48 (27%)
IG_like 294..390 CDD:214653 20/98 (20%)
Ig 296..387 CDD:143165 18/92 (20%)
lrfn2XP_031758515.1 LRR_8 51..111 CDD:404697 16/61 (26%)
leucine-rich repeat 53..76 CDD:275380 5/24 (21%)
leucine-rich repeat 77..100 CDD:275380 7/22 (32%)
LRR_8 100..160 CDD:404697 17/59 (29%)
leucine-rich repeat 101..124 CDD:275380 9/22 (41%)
leucine-rich repeat 125..148 CDD:275380 4/22 (18%)
LRR_8 148..208 CDD:404697 18/59 (31%)
leucine-rich repeat 150..173 CDD:275380 5/22 (23%)
leucine-rich repeat 174..197 CDD:275380 9/22 (41%)
LRRCT 241..285 CDD:214507 13/47 (28%)
Ig 288..375 CDD:416386 18/110 (16%)
Ig strand A 288..291 CDD:409353 0/2 (0%)
Ig strand A' 295..298 CDD:409353 0/2 (0%)
Ig strand B 304..312 CDD:409353 2/7 (29%)
Ig strand C 318..323 CDD:409353 3/10 (30%)
Ig strand C' 326..328 CDD:409353 0/1 (0%)
Ig strand D 334..338 CDD:409353 0/3 (0%)
Ig strand E 341..345 CDD:409353 1/3 (33%)
Ig strand F 355..362 CDD:409353 3/6 (50%)
Ig strand G 365..375 CDD:409353 2/9 (22%)
fn3 417..485 CDD:394996
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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