DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pect and PCYT1B

DIOPT Version :9

Sequence 1:	NP_723789.2	Gene:	Pect / 34716	FlyBaseID:	FBgn0032482	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_004836.2	Gene:	PCYT1B / 9468	HGNCID:	8755	Length:	369	Species:	Homo sapiens

Alignment Length:	182	Identity:	57/182 - (31%)
Similarity:	99/182 - (54%)	Gaps:	20/182 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 KDVRVWCDGCYDMVHFGHANSLRQAKAL--GDKVIVGIHTDEEITKHKGPPVFTEEERVKMVKGI 81
            :.|||:.||.:|:.|.|||.:|.|||.|  ...::||:.:|:...|.||..|..|.||.:.::..
Human    75 RPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNEAERYEALRHC 139

  Fly    82 KWVDEVVLGAPYVTTLDVLDQNNCDFCVHGDDITMTAEGV-DTYHLVKSANRYKEVKRTAGVSTT 145
            ::||||:..||:..|.:.|:::..||..| |||..::.|. |.|..:|.|..:...:||.|:||:
Human   140 RYVDEVIRDAPWTLTPEFLEKHKIDFVAH-DDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTS 203

  Fly   146 DLVGRML----LLTRNHFRQG------------SAEYDIEKEVSILKRQIKS 181
            |::.|::    :..|.:.::|            ...|..:.:|..:|.::|:
Human   204 DIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKRYRFQNQVDKMKEKVKN 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pect	NP_723789.2	PTZ00308	16..381	CDD:140329	57/182 (31%)
		CCT	19..165	CDD:173925	53/164 (32%)
		ECT	223..373	CDD:173924
PCYT1B	NP_004836.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..27
		PLN02413	72..314	CDD:215229	57/182 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	309..369
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0615
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810