DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pect and Pcyt2

DIOPT Version :9

Sequence 1:	NP_723789.2	Gene:	Pect / 34716	FlyBaseID:	FBgn0032482	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_446020.1	Gene:	Pcyt2 / 89841	RGDID:	619970	Length:	404	Species:	Rattus norvegicus

Alignment Length:	387	Identity:	241/387 - (62%)
Similarity:	290/387 - (74%)	Gaps:	16/387 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 RKDVRVWCDGCYDMVHFGHANSLRQAKALGDKVIVGIHTDEEITKHKGPPVFTEEERVKMVKGIK 82
            ::.|||||||||||||:||:|.||||:|:||.:|||:||||||.|||||||||:|||.|||:.||
  Rat    20 QRTVRVWCDGCYDMVHYGHSNQLRQARAMGDYLIVGVHTDEEIAKHKGPPVFTQEERYKMVQAIK 84

  Fly    83 WVDEVVLGAPYVTTLDVLDQNNCDFCVHGDDITMTAEGVDTYHLVKSANRYKEVKRTAGVSTTDL 147
            ||||||..|||||||:.||::||||||||:|||:|.:|.|||..||.|.||:|.|||.|||||||
  Rat    85 WVDEVVPAAPYVTTLETLDKHNCDFCVHGNDITLTVDGRDTYEEVKQAGRYRECKRTQGVSTTDL 149

  Fly   148 VGRMLLLTRNHF--RQGSAEYDIEKEVSILKRQIKSHP-------GSSNMGQDSAAKSPWTGCSQ 203
            ||||||:|:.|.  ::.|:||. |...|..|   ..||       .|....|....:|||||.||
  Rat   150 VGRMLLVTKAHHSSQEMSSEYR-EYADSFGK---PPHPTPAGDTLSSEVSSQCPGGQSPWTGVSQ 210

  Fly   204 FLPTTQKIIQFSDGKSPNPGDKIVYVAGAFDLFHVGHLDFLEKAKKLG--DYLIVGLHTDPVVNS 266
            ||.|:||||||:.||.|.||:.::||||||||||:||:|||::..||.  .|:|.|||.|..||.
  Rat   211 FLQTSQKIIQFASGKEPQPGETVIYVAGAFDLFHIGHVDFLQEVHKLAKRPYVIAGLHFDQEVNR 275

  Fly   267 YKGSNYPIMNLHERVLSVLACKFVNEVVIGAPYCVTEELLEHFKIDVVCHGRTPIALENGKIDPY 331
            |||.||||||||||.||||||::|:||||||||.||.|||.|||:|:||||:|.|..:....|||
  Rat   276 YKGKNYPIMNLHERTLSVLACRYVSEVVIGAPYSVTAELLNHFKVDLVCHGKTEIVPDRDGSDPY 340

  Fly   332 AVPKTRAIFELIDSGNEMTTERIVERIISHRLEYERRNQAKEKKEIEAFEALQRQKQTQKAG 393
            ..||.|.||..||||:::||:.||:|||.:|||||.|||.||.||:...||| ||::.|..|
  Rat   341 EEPKRRGIFCQIDSGSDLTTDLIVQRIIKNRLEYEARNQKKEAKELAFLEAL-RQQEAQPRG 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pect	NP_723789.2	PTZ00308	16..381	CDD:140329	234/373 (63%)
		CCT	19..165	CDD:173925	105/147 (71%)
		ECT	223..373	CDD:173924	96/151 (64%)
Pcyt2	NP_446020.1	PTZ00308	22..390	CDD:140329	234/371 (63%)
Pcyt2	NP_446020.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	173..201		6/30 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354464
Domainoid	1	1.000	207	1.000	Domainoid score	I2797
eggNOG	1	0.900	-	-		E1_COG0615
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2143
Inparanoid	1	1.050	477	0.198	Inparanoid score	I1421
OMA	1	1.010	-	-		QHG53814
OrthoDB	1	1.010	-	-		D302792at33208
OrthoFinder	1	1.000	-	-		FOG0003672
OrthoInspector	1	1.000	-	-		oto98765
orthoMCL	1	0.900	-	-		OOG6_100945
Panther	1	1.100	-	-	LDO	PTHR45780
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3035
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770