Protein Alignment Pect and PCYT1A

DIOPT Version :10

• Sequence 1: NP_723789.2
• Gene: Pect / 34716
• FlyBaseID: FBgn0032482
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_005008.2
• Gene: PCYT1A / 5130
• HGNCID: 8754
• Length: 367
• Species: Homo sapiens
• Alignment Length: 181
• Identity: 60/181 - (33%)
• Similarity: 98/181 - (54%)
• Gaps: 20/181 - (11%)

  Fly    19 KDVRVWCDGCYDMVHFGHANSLRQAKAL--GDKVIVGIHTDEEITKHKGPPVFTEEERVKMVKGI 81
            :.|||:.||.:|:.|.|||.:|.|||.|  ...:|||:.:||.....||..|..|.||...|:..
Human    75 RPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHC 139

  Fly    82 KWVDEVVLGAPYVTTLDVLDQNNCDFCVHGDDITMTAEGV-DTYHLVKSANRYKEVKRTAGVSTT 145
            ::|||||..||:..|.:.|.::..||..| |||..::.|. |.|..:|.|..:...:||.|:||:
Human   140 RYVDEVVRNAPWTLTPEFLAEHRIDFVAH-DDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTS 203

  Fly   146 DLVGRML----LLTRNHFRQG------------SAEYDIEKEVSILKRQIK 180
            |::.|::    :..|.:.::|            ..:|.:::.|..:|:::|
Human   204 DIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pect	NP_723789.2	PTZ00308	16..381	CDD:140329	60/181 (33%)
PCYT1A	NP_005008.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..33
		CCT	75..224	CDD:173925	55/149 (37%)
		Amphipathic. /evidence=ECO:0000255	228..287		4/27 (15%)
		Autoinhibitory (AI). /evidence=ECO:0000250|UniProtKB:P19836	272..293
		Amphipathic. /evidence=ECO:0000255	298..315
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	313..367