DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pect and pcyt2

DIOPT Version :9

Sequence 1:	NP_723789.2	Gene:	Pect / 34716	FlyBaseID:	FBgn0032482	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_001006037.1	Gene:	pcyt2 / 450016	ZFINID:	ZDB-GENE-041010-132	Length:	397	Species:	Danio rerio

Alignment Length:	396	Identity:	231/396 - (58%)
Similarity:	294/396 - (74%)	Gaps:	22/396 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EANGDTSACNGYSDKQRKDVRVWCDGCYDMVHFGHANSLRQAKALGDKVIVGIHTDEEITKHKGP 66
            |.....|:.....:|:::.:||||||||||||:||:|.||||||:||.::||:||||||.|||||
Zfish    12 EDRAQPSSSTHSPEKRKRVIRVWCDGCYDMVHYGHSNQLRQAKAMGDYLVVGVHTDEEIAKHKGP 76

  Fly    67 PVFTEEERVKMVKGIKWVDEVVLGAPYVTTLDVLDQNNCDFCVHGDDITMTAEGVDTYHLVKSAN 131
            ||||:.||.||::.||||||:|.||||||||:.||:.||||||||||||:|.:|.|||..||...
Zfish    77 PVFTQAERYKMIRAIKWVDEIVEGAPYVTTLETLDKYNCDFCVHGDDITLTVDGKDTYDEVKRTG 141

  Fly   132 RYKEVKRTAGVSTTDLVGRMLLLTR-NHFRQGSAEYDIEKEVSILKRQIKSHPGSSNMGQDSAAK 195
            ||:|.|||.|||||||||||||||: :|....:|.|.:.               :.|.|:.....
Zfish   142 RYRECKRTQGVSTTDLVGRMLLLTKAHHSNIDNAAYQVH---------------TDNFGKGPKGH 191

  Fly   196 SPWTGCSQFLPTTQKIIQFSDGKSPNPGDKIVYVAGAFDLFHVGHLDFLE----KAKKLGDYLIV 256
            |||||.||||.|:||||||:.||.|.|||.|:||||||||||:||:||||    :|:|  .|:||
Zfish   192 SPWTGVSQFLQTSQKIIQFASGKEPQPGDTIIYVAGAFDLFHIGHVDFLETVHGQAEK--PYVIV 254

  Fly   257 GLHTDPVVNSYKGSNYPIMNLHERVLSVLACKFVNEVVIGAPYCVTEELLEHFKIDVVCHGRTPI 321
            |||.|..||.|||.||||||:|||:||||||::|:||||||||.|.::||:|||:|:||||:|.:
Zfish   255 GLHFDQEVNRYKGKNYPIMNIHERILSVLACRYVSEVVIGAPYAVEKDLLDHFKVDLVCHGKTNV 319

  Fly   322 ALENGKIDPYAVPKTRAIFELIDSGNEMTTERIVERIISHRLEYERRNQAKEKKEIEAFEALQRQ 386
            ..:....||||.||.|.||.::||.|.:||:.||:|||.:||::|.|||.||.||:...:||:|:
Zfish   320 FPDADGTDPYAEPKKRGIFRILDSSNNLTTDDIVQRIIENRLQFEARNQKKEAKEMAVLQALKRK 384

  Fly   387 KQTQKA 392
            .::.|:
Zfish   385 DESVKS 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pect	NP_723789.2	PTZ00308	16..381	CDD:140329	225/369 (61%)
		CCT	19..165	CDD:173925	102/146 (70%)
		ECT	223..373	CDD:173924	94/153 (61%)
pcyt2	NP_001006037.1	PTZ00308	20..374	CDD:140329	223/370 (60%)
		CCT	29..173	CDD:173925	102/143 (71%)
		ECT	219..371	CDD:173924	94/153 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596770
Domainoid	1	1.000	206	1.000	Domainoid score	I2867
eggNOG	1	0.900	-	-		E1_COG0615
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2143
Inparanoid	1	1.050	481	1.000	Inparanoid score	I1423
OMA	1	1.010	-	-		QHG53814
OrthoDB	1	1.010	-	-		D302792at33208
OrthoFinder	1	1.000	-	-		FOG0003672
OrthoInspector	1	1.000	-	-		oto39149
orthoMCL	1	0.900	-	-		OOG6_100945
Panther	1	1.100	-	-	LDO	PTHR45780
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2100
SonicParanoid	1	1.000	-	-		X3035
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800