DRSC/TRiP Functional Genomics Resources

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Protein Alignment Edem2 and Man1b1

DIOPT Version :10

Sequence 1:NP_609611.1 Gene:Edem2 / 34714 FlyBaseID:FBgn0032480 Length:801 Species:Drosophila melanogaster
Sequence 2:NP_001025154.1 Gene:Man1b1 / 227619 MGIID:2684954 Length:658 Species:Mus musculus


Alignment Length:492 Identity:157/492 - (31%)
Similarity:237/492 - (48%) Gaps:79/492 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 KERAELREEAR---DMFYHAYNAYMQNAYPADELMPLSCKGRYRGVTPSRGDMDDILGNFSMTLV 106
            ||.|...|..:   :.|.||:..|.:.|:..|||.|:|            ....:..| ..:||:
Mouse   200 KEPAPPNERQKGVIEAFLHAWKGYQKFAWGHDELKPVS------------KTFSEWFG-LGLTLI 251

  Fly   107 DTLDTLVLLGDFTEFDHAVKLVIRDVQFDSDIIVSVFETNIRMVGGLLSAHILAEYLQKHADTMH 171
            |.|||:.:||...||..|.|.|..::.|..::.|::||:.||::|||||.:.|:      .|::.
Mouse   252 DALDTMWILGLKQEFKQARKWVSENLDFQKNVDVNLFESTIRILGGLLSTYHLS------GDSLF 310

  Fly   172 WYKGELLEMSRELGYRLLPAFNTSTGIPHARVNLRLGMKDPMLKKSRETCTACAGTILLEFAALS 236
            ..|.|      :.|.||:|||.|.:.||::.||:..|........|..| .|...:|.|||..||
Mouse   311 LTKAE------DFGKRLMPAFTTPSKIPYSDVNIGTGFAHSPQWTSDST-VAEVTSIQLEFRELS 368

  Fly   237 RLTGDPIFEVRAHAAMDALWKLRHRGSDLMGTVLNVHSGDWVRRDSGV---GAGIDSYYEYLFKS 298
            ||||...|:.........:..|..:...|:...:|.:||.:..  .||   ||..|||||||.|.
Mouse   369 RLTGIKKFQEAVEEVTKHIHSLSGKKDGLVPMFINTNSGLFTH--PGVFTLGARADSYYEYLLKQ 431

  Fly   299 YVLLG--DDKYLARFNRHYNAVMKYV--SEGPMLLDVLMHRPHAKSKNFMDSLLAFWPG---LQV 356
            ::..|  :.:.|..:.:....:..::  ...|..|..:....|.:....||.|:.|.||   |.|
Mouse   432 WIQGGKKETQLLEDYVKAIEGIKAHLLRQSQPRKLTFVGELAHGRFSAKMDHLVCFLPGTLALGV 496

  Fly   357 LSG------DLKPAVQTHEMLYQV-MQMHTFI-PEAFTVDFQIHWGQHP---------------- 397
            ..|      ||..|:.  |..||: .||.|.: ||.      .|:..:|                
Mouse   497 HHGLPADHMDLARALM--ETCYQMNQQMETGLSPEI------AHFNMYPRADHKDVEVKPADRHN 553

  Fly   398 -LRPEFIESTYFLYRATGDHHYLQVGKKALKTLQQHAKV-SCGYAAVNDVRTG---KHEDRMDSF 457
             ||||.:||.::|||.|.|..|...|.:.|::..::.:| |.||:::|:|:..   :..|:|:||
Mouse   554 LLRPETVESLFYLYRVTRDRKYQDWGWEILQSFNKYTRVPSGGYSSINNVQNSHKPEPRDKMESF 618

  Fly   458 VLSETIKYLFLLFSDPQDLIINVDEFVFTTEAHLLPL 494
            .:.||:|||:|||||..:| :::|..||.||||.||:
Mouse   619 FVGETLKYLYLLFSDDLEL-LSLDSCVFNTEAHPLPI 654

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Edem2NP_609611.1 Glyco_hydro_47 57..494 CDD:460241 152/475 (32%)
PA_EDEM3_like 645..770 CDD:239041
Man1b1NP_001025154.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 123..142
Glyco_hydro_47 215..654 CDD:460241 152/475 (32%)
Blue background indicates that the domain is not in the aligned region.

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