DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16974 and RLP38

DIOPT Version :9

Sequence 1:	NP_001246018.1	Gene:	CG16974 / 34713	FlyBaseID:	FBgn0032479	Length:	1257	Species:	Drosophila melanogaster
Sequence 2:	NP_188953.1	Gene:	RLP38 / 821887	AraportID:	AT3G23120	Length:	784	Species:	Arabidopsis thaliana

Alignment Length:	451	Identity:	111/451 - (24%)
Similarity:	171/451 - (37%)	Gaps:	124/451 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   215 LECLHW------AIPLAVRRVKVLEMSGNRLSNCSLLNLQYMKQLQEL-HLDRSELTY---LPQR 269
            ::|..|      ||...|..:|:..:|   .::.||.:...:.:||.| |||.|....   :|..
plant    68 IDCCSWGGVTCDAILGEVISLKLYFLS---TASTSLKSSSALFKLQHLTHLDLSNCNLQGEIPSS 129

  Fly   270 FLGELSELRMLNLSQN-LLTELPRDIFVGAL-KLERLYLSGN--------------RLSVLPF-- 316
             :..||.|..|:||.| |:.|:|..|  |.| :||.:.|.||              :||:|..
plant   130 -IENLSHLTHLDLSTNHLVGEVPASI--GNLNQLEYIDLRGNHLRGNIPTSFANLTKLSLLDLHE 191

  Fly   317 -------MLFQTAADLQVLDLSDNRLLSF----------------PDNFFA--------RNGQLR 350
                   ::......|.:||||.|...||                .:|.|.        :...|.
plant   192 NNFTGGDIVLSNLTSLAILDLSSNHFKSFFSADLSGLHNLEQIFGNENSFVGLFPASLLKISSLD 256

  Fly   351 QLHLQRNQLKS-----------------------IGK--HSLYSLRELRQLDLSQNSLSVIDRKA 390
            ::.|.:||.:.                       ||:  .||..|..|..||||.|:...:..::
plant   257 KIQLSQNQFEGPIDFGNTSSSSRLTMLDISHNNFIGRVPSSLSKLVNLELLDLSHNNFRGLSPRS 321

  Fly   391 FESLDHLLALNVSGNNLTLLSSIIFQSLHALRQLDLSRNQFKQLPS-----------GLFQRQRS 444
            ...|.:|.:|::|.|.|.............|:.:|||.|.|..|..           ||.....|
plant   322 ISKLVNLTSLDISYNKLEGQVPYFIWKPSNLQSVDLSHNSFFDLGKSVEVVNGAKLVGLNLGSNS 386

  Fly   445 LVLLRIDETPIEQFSNWISRYDESLVDPQVLHRLRYLSVQQNRKLTYLPATLFANTPNIRELLLA 509
            |      :.||.|   ||..:          ..:.:|.:..||....:|..| .|:.:...|.|.
plant   387 L------QGPIPQ---WICNF----------RFVFFLDLSDNRFTGSIPQCL-KNSTDFNTLNLR 431

  Fly   510 ENGLLQ-LPTQISGLSRLQRLSVR-GNSLGSLPENIKELRQLHYLNILGNEYQCDCSMYWL 568
            .|.|.. ||......:.|:.|.|. .|.:|.||:::...:.:.:||:.||:.: |...:||
plant   432 NNSLSGFLPELCMDSTMLRSLDVSYNNFVGKLPKSLMNCQDMEFLNVRGNKIK-DTFPFWL 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16974	NP_001246018.1	leucine-rich repeat	206..228	CDD:275380	5/18 (28%)
		leucine-rich repeat	229..252	CDD:275380	4/22 (18%)
		LRR_RI	<246..433	CDD:238064	66/264 (25%)
		LRR_8	251..311	CDD:290566	26/79 (33%)
		leucine-rich repeat	253..276	CDD:275380	9/26 (35%)
		leucine-rich repeat	277..300	CDD:275380	11/24 (46%)
		leucine-rich repeat	301..324	CDD:275380	8/45 (18%)
		LRR_8	325..383	CDD:290566	25/106 (24%)
		leucine-rich repeat	325..348	CDD:275380	10/46 (22%)
		leucine-rich repeat	349..372	CDD:275380	9/47 (19%)
		LRR_RI	351..>557	CDD:238064	57/243 (23%)
		LRR_8	371..431	CDD:290566	17/59 (29%)
		leucine-rich repeat	373..396	CDD:275380	7/22 (32%)
		leucine-rich repeat	397..420	CDD:275380	5/22 (23%)
		leucine-rich repeat	421..444	CDD:275380	9/33 (27%)
		LRR_8	477..536	CDD:290566	16/60 (27%)
		leucine-rich repeat	478..502	CDD:275380	6/23 (26%)
		leucine-rich repeat	503..526	CDD:275380	6/23 (26%)
		Ig	<714..761	CDD:299845
RLP38	NP_188953.1	PLN00113	11..>721	CDD:331614	111/451 (25%)
		leucine-rich repeat	112..135	CDD:275380	7/23 (30%)
		leucine-rich repeat	136..159	CDD:275380	11/24 (46%)
		leucine-rich repeat	160..183	CDD:275380	5/22 (23%)
		leucine-rich repeat	184..206	CDD:275380	3/21 (14%)
		leucine-rich repeat	207..254	CDD:275380	10/46 (22%)
		leucine-rich repeat	255..276	CDD:275380	4/20 (20%)
		leucine-rich repeat	280..303	CDD:275380	5/22 (23%)
		leucine-rich repeat	304..327	CDD:275380	7/22 (32%)
		leucine-rich repeat	352..376	CDD:275380	7/23 (30%)
		leucine-rich repeat	377..397	CDD:275380	9/28 (32%)
		leucine-rich repeat	401..424	CDD:275380	6/23 (26%)
		leucine-rich repeat	425..448	CDD:275380	6/22 (27%)
		leucine-rich repeat	449..472	CDD:275380	7/22 (32%)
		leucine-rich repeat	473..496	CDD:275380	7/20 (35%)
		leucine-rich repeat	523..545	CDD:275380
		leucine-rich repeat	659..682	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000