DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG16974 and RLP35

DIOPT Version :9

Sequence 1:NP_001246018.1 Gene:CG16974 / 34713 FlyBaseID:FBgn0032479 Length:1257 Species:Drosophila melanogaster
Sequence 2:NP_001319521.1 Gene:RLP35 / 820279 AraportID:AT3G11080 Length:943 Species:Arabidopsis thaliana


Alignment Length:800 Identity:189/800 - (23%)
Similarity:299/800 - (37%) Gaps:227/800 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    88 SDSD----EGLWLDAADAGSESVEVEEHELPS---VGHVDPTGNVFKL-NCEHVDLRR--VNQEL 142
            ::||    ||:..|     ::|.||.|.:|..   .|......::|:| |...:||.:  ::.|:
plant    82 NNSDCCNWEGITCD-----TKSGEVIELDLSCSWLYGSFHSNSSLFRLQNLRVLDLTQNDLDGEI 141

  Fly   143 LSQ-------RSSHINYNQLMLAHVPADRSNPLKLPQLE-SLREFSWQ--SS--ELKDETLMELF 195
            .|.       .|.|::||| .|..:|:...|..:|..|. |..:||.|  ||  .|...|.:||.
plant   142 PSSIGNLSHLTSLHLSYNQ-FLGLIPSSIENLSRLTSLHLSSNQFSGQIPSSIGNLSHLTSLELS 205

  Fly   196 TRQ-----PRSFEYMERL-------------------NLAENRLECLHWA-------IPLA---V 226
            :.|     |.|...:..|                   |||  ||..|:.:       ||.:   :
plant   206 SNQFSGQIPSSIGNLSNLTFLSLPSNDFFGQIPSSIGNLA--RLTYLYLSYNNFVGEIPSSFGNL 268

  Fly   227 RRVKVLEMSGNRLSN---CSLLNLQYMKQLQELHLDRSELTYLPQRFLGELSELRMLNLSQNLLT 288
            .::.||::..|:||.   .|||||   .:|..|.|..::.|......:..||.|.....|.|..|
plant   269 NQLIVLQVDSNKLSGNVPISLLNL---TRLSALLLSHNQFTGTIPNNISLLSNLMDFEASNNAFT 330

  Fly   289 -ELPRDIFVGALKLERLYLSGNRLS-VLPFMLFQTAADLQVLDLSDNRLLSFPDNFFAR------ 345
             .||..:| ....|.||.||.|:|: .|.|....:.::||.|.:..|..:.......:|      
plant   331 GTLPSSLF-NIPPLIRLDLSDNQLNGTLHFGNISSPSNLQYLIIGSNNFIGTIPRSLSRFVNLTL 394

  Fly   346 ------NGQLRQLHLQ-RNQLKSIGKHSLYSL--------------RELRQLDLSQNSLSVIDRK 389
                  |.|.|.:... .:.|||:....|..|              :.||.||:|.|.:|..::.
plant   395 FDLSHLNTQCRPVDFSIFSHLKSLDDLRLSYLTTTTIDLNDILPYFKTLRSLDISGNLVSATNKS 459

  Fly   390 AFES---LDHLLALNVSGNNLTLLSSIIFQSLHALRQLDLSRNQFK-QLPSGLFQRQRSLVLLRI 450
            :..|   ...:.:|.:||..:|....|: ::.|.|..||:|.|:.| |:|..|:... :|..|.:
plant   460 SVSSDPPSQSIQSLYLSGCGITDFPEIL-RTQHELGFLDVSNNKIKGQVPGWLWTLP-NLFYLNL 522

  Fly   451 DETPIEQFSNWISRYDESLV-DPQVLH--------------------RLRYLSVQQN-------R 487
            .......|.:...::..|.| .|.::|                    .|..|.:.:|       |
plant   523 SNNTFISFESSSKKHGLSSVRKPSMIHLFASNNNFTGKIPSFICGLRSLNTLDLSENNYNGSIPR 587

  Fly   488 KLTYLPATLFANTPNIRELLLAENGLL-QLPTQISGLSRLQRLSVRGNSL-GSLPENIKELRQLH 550
            .:..|.:|||.       |.|.:|.|. .||..|  ...|:.|.|..|.| |.||.::.....|.
plant   588 CMEKLKSTLFV-------LNLRQNNLSGGLPKHI--FESLRSLDVGHNLLVGKLPRSLIRFSNLE 643

  Fly   551 YLNILGNEYQCDCSMYWLTAWLANTSTSLR--------HQ--MPQ------AQNHSNGS------ 593
            .||:..|... |...:||::........||        |:  .|:      :.||.||:      
plant   644 VLNVESNRIN-DTFPFWLSSLSKLQVLVLRSNAFHGPIHEATFPELRIIDISHNHFNGTLPTEYF 707

  Fly   594 ---------------TNQTPLDSYESIDHQIDALKCQYGYRGDMLRVLSKLNCSVPTVVQFSEPK 643
                           :|:..:.|  .:.:|...:....|...:::|:|     ::.|.:.||..|
plant   708 VKWSAMSSLGKNEDQSNEKYMGS--GLYYQDSMVLMNKGLAMELVRIL-----TIYTALDFSGNK 765

  Fly   644 MHKLLSTAKLECQISGSPVPDIIWVTPRNKILRHHADPDKRPIIIDSKEDA---HQPPSAQELAA 705
            ..              ..:|..|.:.             |..::::...:|   |.|.|...|.|
plant   766 FE--------------GEIPKSIGLL-------------KELLVLNLSNNAFGGHIPSSMGNLTA 803

  Fly   706 LMDESYIQSLNWTRQNSLVG 725
            |      :||: ..||.|.|
plant   804 L------ESLD-VSQNKLTG 816

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG16974NP_001246018.1 leucine-rich repeat 206..228 CDD:275380 9/50 (18%)
leucine-rich repeat 229..252 CDD:275380 10/25 (40%)
LRR_RI <246..433 CDD:238064 57/219 (26%)
LRR_8 251..311 CDD:290566 19/60 (32%)
leucine-rich repeat 253..276 CDD:275380 5/22 (23%)
leucine-rich repeat 277..300 CDD:275380 7/23 (30%)
leucine-rich repeat 301..324 CDD:275380 9/23 (39%)
LRR_8 325..383 CDD:290566 19/84 (23%)
leucine-rich repeat 325..348 CDD:275380 6/34 (18%)
leucine-rich repeat 349..372 CDD:275380 6/37 (16%)
LRR_RI 351..>557 CDD:238064 61/254 (24%)
LRR_8 371..431 CDD:290566 19/62 (31%)
leucine-rich repeat 373..396 CDD:275380 8/25 (32%)
leucine-rich repeat 397..420 CDD:275380 5/22 (23%)
leucine-rich repeat 421..444 CDD:275380 9/23 (39%)
LRR_8 477..536 CDD:290566 19/66 (29%)
leucine-rich repeat 478..502 CDD:275380 8/30 (27%)
leucine-rich repeat 503..526 CDD:275380 7/23 (30%)
Ig <714..761 CDD:299845 5/11 (45%)
RLP35NP_001319521.1 LRRNT_2 39..95 CDD:311940 4/12 (33%)
PLN00113 79..>658 CDD:331614 153/599 (26%)
leucine-rich repeat 103..123 CDD:275380 3/19 (16%)
leucine-rich repeat 127..150 CDD:275380 4/22 (18%)
leucine-rich repeat 151..174 CDD:275380 8/23 (35%)
leucine-rich repeat 175..198 CDD:275380 9/22 (41%)
leucine-rich repeat 199..222 CDD:275380 6/22 (27%)
leucine-rich repeat 223..246 CDD:275380 4/24 (17%)
leucine-rich repeat 247..270 CDD:275380 4/22 (18%)
leucine-rich repeat 271..294 CDD:275380 10/25 (40%)
leucine-rich repeat 295..318 CDD:275380 5/22 (23%)
leucine-rich repeat 319..337 CDD:275380 6/17 (35%)
leucine-rich repeat 343..367 CDD:275380 9/23 (39%)
leucine-rich repeat 368..388 CDD:275380 4/19 (21%)
leucine-rich repeat 392..417 CDD:275380 4/24 (17%)
leucine-rich repeat 443..469 CDD:275380 8/25 (32%)
leucine-rich repeat 470..492 CDD:275380 5/22 (23%)
leucine-rich repeat 493..516 CDD:275380 9/23 (39%)
leucine-rich repeat 517..541 CDD:275380 3/23 (13%)
leucine-rich repeat 542..570 CDD:275380 3/27 (11%)
leucine-rich repeat 571..594 CDD:275380 5/22 (23%)
leucine-rich repeat 596..617 CDD:275380 9/29 (31%)
leucine-rich repeat 618..641 CDD:275380 8/22 (36%)
LRR_8 640..698 CDD:316378 12/58 (21%)
leucine-rich repeat 642..665 CDD:275380 7/23 (30%)
leucine-rich repeat 716..803 CDD:275380 18/120 (15%)
PLN00113 <758..864 CDD:331614 18/92 (20%)
leucine-rich repeat 804..825 CDD:275380 6/19 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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