DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG16974 and CG4950

DIOPT Version :9

Sequence 1:NP_001246018.1 Gene:CG16974 / 34713 FlyBaseID:FBgn0032479 Length:1257 Species:Drosophila melanogaster
Sequence 2:NP_001261934.1 Gene:CG4950 / 39783 FlyBaseID:FBgn0036587 Length:574 Species:Drosophila melanogaster


Alignment Length:529 Identity:115/529 - (21%)
Similarity:211/529 - (39%) Gaps:125/529 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   115 SVGHVDPTGNVFKLNCEHVD---LRRVNQELLSQRSSHINYNQ-LMLAHVPADRSNPLK------ 169
            ::...|.:|....|.|:..|   ...||:...:.....:.::| :::.::|.  .|.:|      
  Fly    17 AISSCDGSGGDIPLRCDEYDSMGYMDVNEAFCTVTGFTVTHSQNVVIKNIPP--GNMVKFMKFYE 79

  Fly   170 -------------LPQLESLREFSWQSSELKDETLMELFTRQPRSFEYMERLNLAENRLECLHWA 221
                         .|.|::|        ::.:..::||......:...:..||||.|.|..:..:
  Fly    80 STLLYMPFHLFETFPYLKTL--------DVSNTNILELTRNAFSAASNLTYLNLAYNNLTSIQTS 136

  Fly   222 IPLAVRRVKVLEMSGNRLSNCSLLNLQYMKQLQELHLDRSELTYLPQRFLGELSELRMLNLSQNL 286
            :.:....:..|::|.|.:|:.|:.....:..:.:::|..:.|..|......:...|..::...||
  Fly   137 VFIGANVLMRLDLSYNEISSLSVNAFCGLHTISQIYLTGNLLKELHNDIFKDNEYLEKVSFEGNL 201

  Fly   287 LTELPRDIFVGALKLERLYLSGNRLSVLPFMLFQTAADLQVLDLSDNRLLSFPDNFFARNGQLRQ 351
            ||.:..::|....:::.:.||.|||..:....|..||.|:.|.||.|.|.:|.   ......:.|
  Fly   202 LTSIQPEVFRNMRRIKEVNLSNNRLIFIHPDTFADAASLENLVLSYNELKNFQ---LTEKNIVHQ 263

  Fly   352 LHLQRNQLKSI---------GKHS------LYSLRELRQLDLSQNSLSVIDRKAFESLDHLLALN 401
            |||..|.|.::         ..|:      |:....:..||||.|.||.|..  ..::.|:|.|:
  Fly   264 LHLDNNYLTNLTINATRFVRASHNQISELFLHQSLHIETLDLSANKLSSISN--ITNITHMLYLD 326

  Fly   402 VSGNNLTLLSSIIFQSLHALRQLDLSRNQFKQLPSGLFQRQR----------SLVLLRIDETPIE 456
            ||.|.:..|:...|..|..||.|:|.....::|..|:|.:|:          :|.:|.:|     
  Fly   327 VSDNPIGPLNISTFSQLKRLRGLNLRGTGIRELKFGMFSKQKYLEELDLSFNNLTILNLD----- 386

  Fly   457 QFSNWISRYDESLVD-------------PQVLHRLRYLSVQQNR-KLTYL--------------- 492
            .|..:::...:.|:|             .:...:|:.|.|.:|| ..:||               
  Fly   387 MFVPYLTNLKKFLIDGNGLTELQGNRTFSEAFPQLQKLGVSRNRFNCSYLHHLLIPPSLPESVVL 451

  Fly   493 ---PATLFANTPNIREL-------------LLAENGLLQLPTQISGLSRLQRLSVRGNSLGSLPE 541
               |.|....||:||::             ..||...|:        |::|.||.:.:.:||..:
  Fly   452 NIEPDTNLDETPHIRDVSCISQSQEVVNASFTAEESKLE--------SQIQMLSKQLDIVGSHSK 508

  Fly   542 NIKELRQLH 550
            |:    :||
  Fly   509 NL----ELH 513

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG16974NP_001246018.1 leucine-rich repeat 206..228 CDD:275380 6/21 (29%)
leucine-rich repeat 229..252 CDD:275380 5/22 (23%)
LRR_RI <246..433 CDD:238064 53/201 (26%)
LRR_8 251..311 CDD:290566 12/59 (20%)
leucine-rich repeat 253..276 CDD:275380 3/22 (14%)
leucine-rich repeat 277..300 CDD:275380 6/22 (27%)
leucine-rich repeat 301..324 CDD:275380 7/22 (32%)
LRR_8 325..383 CDD:290566 20/72 (28%)
leucine-rich repeat 325..348 CDD:275380 7/22 (32%)
leucine-rich repeat 349..372 CDD:275380 8/37 (22%)
LRR_RI 351..>557 CDD:238064 64/270 (24%)
LRR_8 371..431 CDD:290566 21/59 (36%)
leucine-rich repeat 373..396 CDD:275380 8/22 (36%)
leucine-rich repeat 397..420 CDD:275380 8/22 (36%)
leucine-rich repeat 421..444 CDD:275380 8/32 (25%)
LRR_8 477..536 CDD:290566 20/90 (22%)
leucine-rich repeat 478..502 CDD:275380 10/42 (24%)
leucine-rich repeat 503..526 CDD:275380 6/35 (17%)
Ig <714..761 CDD:299845
CG4950NP_001261934.1 leucine-rich repeat 96..119 CDD:275380 4/30 (13%)
LRR_8 118..178 CDD:290566 12/59 (20%)
leucine-rich repeat 120..143 CDD:275380 6/22 (27%)
leucine-rich repeat 144..167 CDD:275380 5/22 (23%)
leucine-rich repeat 168..191 CDD:275380 3/22 (14%)
LRR_8 192..250 CDD:290566 19/57 (33%)
leucine-rich repeat 192..215 CDD:275380 6/22 (27%)
LRR_RI <207..432 CDD:238064 60/234 (26%)
leucine-rich repeat 216..239 CDD:275380 7/22 (32%)
leucine-rich repeat 240..299 CDD:275380 15/61 (25%)
LRR_8 299..356 CDD:290566 21/58 (36%)
leucine-rich repeat 300..321 CDD:275380 8/22 (36%)
leucine-rich repeat 322..345 CDD:275380 8/22 (36%)
LRR_8 344..405 CDD:290566 14/65 (22%)
leucine-rich repeat 346..365 CDD:275380 6/18 (33%)
leucine-rich repeat 370..394 CDD:275380 4/28 (14%)
leucine-rich repeat 395..420 CDD:275380 2/24 (8%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45453814
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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