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Protein Alignment CG16974 and Islr2

DIOPT Version :9

Sequence 1:	NP_001246018.1	Gene:	CG16974 / 34713	FlyBaseID:	FBgn0032479	Length:	1257	Species:	Drosophila melanogaster
Sequence 2:	XP_003750572.2	Gene:	Islr2 / 100910729	RGDID:	6497037	Length:	746	Species:	Rattus norvegicus

Alignment Length:	437	Identity:	102/437 - (23%)
Similarity:	154/437 - (35%)	Gaps:	142/437 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   371 RELRQ-----------LDLSQNSLSVIDRKAFESLDHLLALNVSGNNLTLLSSIIFQSLHALRQL 424
            :|||:           |.||.|.::|:.|.||.::..:.:|.::.:.:..:.|.....|..|:.|
  Rat    41 KELREVPEGLPANVTTLSLSANKITVLRRGAFVNVTQVTSLWLAHSEVRTVESGALAVLSQLKNL 105

  Fly   425 DLSRNQFKQLPSGLFQRQRSLVLLRIDETPIEQFSNWISRYDESLVDPQVLHRLRYLSVQQNRKL 489
            |||.|.....|                         |        .|.:.|..|:.|.:..|| |
  Rat   106 DLSHNLISNFP-------------------------W--------SDLRNLSALQLLKMNHNR-L 136

  Fly   490 TYLPATLFANTPNIRELLLAENGLLQLPTQISGLSRLQRLSVRGNSLGSLPENIKELRQLHYLNI 554
            ..||.......|::|.|.:..|             ||:.|.         |.....|..|.:|.:
  Rat   137 GSLPRDALGALPDLRSLRINNN-------------RLRTLE---------PGTFDALSALSHLQL 179

  Fly   555 LGNEYQCDCSMYWLTAWLANTSTSLRHQMPQAQNHSNGSTNQTPLDSYESIDHQIDALKCQY--G 617
            ..|.:.|.|.:.||.||.|:|..||    |:.                       |::.|..  .
  Rat   180 YHNPFHCSCGLVWLQAWAASTRVSL----PEP-----------------------DSIACASPPE 217

  Fly   618 YRGDMLRVLSKLNCSVPTVVQFSEP-------KMHKLLSTAKLECQISGSPVPDIIW-------- 667
            .:|..:..|..|.|:.|:|...:||       .:...||.. |.|...|.|.|.:.|
  Rat   218 LQGVPVHRLPALPCAPPSVRLSAEPPPEAPGTPLRAGLSFL-LHCVAEGHPTPRLQWQLQIPGGT 281

  Fly   668 ---VTPRNKILRHHADPDKRPIIIDSKE---DAHQP-----PSAQELAALMDESYIQSLNWTRQN 721
               |.|   :|....|..::   :|..|   |..||     |:.....|           |....
  Rat   282 VVLVPP---VLSKEEDGGEK---VDDGEGDGDEDQPTQTEAPTPTPAPA-----------WPAPP 329

  Fly   722 SLVGRRVVLVENGSLLVHNISRIDSGLYTCYAFNVMGKASAGLRLYI 768
            :.  .|.:.:.||||||..:|..::|:|||.|.|.:|..|..||:.:
  Rat   330 AT--PRFLALANGSLLVPLLSAKEAGIYTCRAHNELGTNSTSLRVTV 374

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.