DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rsph1 and JPH3

DIOPT Version :9

Sequence 1:NP_609609.1 Gene:Rsph1 / 34712 FlyBaseID:FBgn0032478 Length:344 Species:Drosophila melanogaster
Sequence 2:NP_065706.2 Gene:JPH3 / 57338 HGNCID:14203 Length:748 Species:Homo sapiens


Alignment Length:321 Identity:71/321 - (22%)
Similarity:108/321 - (33%) Gaps:74/321 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    25 GLYIGGRNAAGQRQGRGWAILPNGDQYDGNYRKGRRHG---IGVYVFKDGSRYYGQYRCGKRCG- 85
            |.|.||.. .|:..|.|....|.|   .|.|.....||   :|||.:..|:.|.|.:..|||.| 
Human    13 GSYCGGWE-DGKAHGHGVCTGPKG---QGEYTGSWSHGFEVLGVYTWPSGNTYQGTWAQGKRHGI 73

  Fly    86 ----RGIFIYP------------------DGSVYEGNWRKNLKHGKGRYKYVNGDNYSGDWFKGQ 128
                :|.::|.                  :|:.|||.|...|:.|.|...|.:|..|.|.|..|.
Human    74 GLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGM 138

  Fly   129 RHGVGIYHFNSGKDGCCLSVRMKATWNSNMRTGPFELYIGNEDKCTILHGIWDNLYPSGPAVF-- 191
            |.|.|:..        .:...|.|...|.:||....|. ......|.||..........|||.  
Human   139 RQGYGVRQ--------SVPYGMAAVIRSPLRTSINSLR-SEHTNGTALHPDASPAVAGSPAVSRG 194

  Fly   192 ------------------SFNNRYLLLGYFLPASYNMKAISNEDEMED---AEERLEDEMGEAEP 235
                              ....|.||.|..|..|.:..:::::...:.   :|..:......|..
Human   195 GFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASD 259

  Fly   236 MEPTLWFAQEMAVYDFSLLPQEPVPLAISDSELSVCSLSTEPSMRSEEKISWYGEGEEAEG 296
            :..|:            .|.:....||:.:.::...:..|.......:|.|.:|..:.::|
Human   260 IHSTI------------SLGEAEAELAVIEDDIDATTTETYVGEWKNDKRSGFGVSQRSDG 308

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rsph1NP_609609.1 MORN 51..73 CDD:280628 8/24 (33%)
MORN 72..93 CDD:197832 8/43 (19%)
MORN 95..116 CDD:197832 8/20 (40%)
MORN 118..137 CDD:197832 7/18 (39%)
JPH3NP_065706.2 MORN 1 15..37 8/25 (32%)
MORN 2 39..60 7/20 (35%)
MORN 3 61..82 7/20 (35%)
MORN 4 83..105 1/21 (5%)
MORN 107..129 CDD:280628 9/21 (43%)
MORN 5 107..129 9/21 (43%)
MORN 6 130..152 7/29 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 230..259 2/28 (7%)
MORN 7 288..310 4/21 (19%)
MORN 311..333 CDD:280628
MORN 8 311..333
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 416..496
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 526..597
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 624..649
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG4642
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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