DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rsph1 and jph1b

DIOPT Version :9

Sequence 1:	NP_609609.1	Gene:	Rsph1 / 34712	FlyBaseID:	FBgn0032478	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_001037813.1	Gene:	jph1b / 556485	ZFINID:	ZDB-GENE-060616-389	Length:	673	Species:	Danio rerio

Alignment Length:	337	Identity:	80/337 - (23%)
Similarity:	119/337 - (35%)	Gaps:	109/337 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 GLYIGGRNAAGQRQGRGWAILPNGD-QYDGNYRKGRRHGIGVYVFKDGSRYYGQYRCGKRCGRGI 88
            |.:.||.. .|:..|.|....|.|. :|.|::..| ...:|||.:..|:.|.|.:..|||.|.|:
Zfish    12 GTFCGGWE-DGKAHGHGICTGPKGQGEYSGSWSNG-FEVVGVYTWPSGNTYKGYWAQGKRHGLGV 74

  Fly    89 -----FIY--------------------PDGSVYEGNWRKNLKHGKGRYKYVNGDNYSGDWFKGQ 128
                 ::|                    |  :.|||.|...|:.|.|...|.:|..|.|.|..|.
Zfish    75 ESKGRWLYRGEWSHGFKGRYGVRQSLNTP--ARYEGTWSNGLQDGYGVETYGDGGTYQGQWMGGM 137

  Fly   129 RHGVGIYHFNSGKDGCCLSVRMKATWNSNMRTGPFELYIGNEDKCTILHGIWDNLYPS-----GP 188
            |||.|:.  .|...|....:|      |.:||....|. ..:...::||   |::..|     |.
Zfish   138 RHGYGVR--QSVPYGMATVIR------SPLRTSLASLR-SEQSNGSVLH---DHMSDSPAGTRGG 190

  Fly   189 AVFSFNNRYLLLGYFLPASYNMKAISNEDEMEDAEERLEDEMGEAEPMEPTLWFAQEMAVYDFSL 253
            .|.:|:                    ::.|:...:::.....|..                 |..
Zfish   191 FVLNFH--------------------SDSEVVSGKKKGLFRRGSL-----------------FGS 218

  Fly   254 LPQEPVPLAISDSELSVCSLSTEPSMRSEEKIS-----------WYGEGEEAEGEEGGEMECFPC 307
            |.|    |..|||..|:.  |...|.||:..:|           .:|:||.|:       |..|.
Zfish   219 LKQ----LRKSDSRSSIS--SKRSSARSDATMSRISSSDANSTISFGDGEVAD-------EYMPA 270

  Fly   308 ECDLTDVSEVET 319
            | |..|.:..|:
Zfish   271 E-DNVDATTTES 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rsph1	NP_609609.1	MORN	51..73	CDD:280628	7/21 (33%)
		MORN	72..93	CDD:197832	8/45 (18%)
		MORN	95..116	CDD:197832	8/20 (40%)
		MORN	118..137	CDD:197832	8/18 (44%)
jph1b	NP_001037813.1	MORN	106..128	CDD:280628	9/21 (43%)
jph1b	NP_001037813.1	MORN	305..327	CDD:280628
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4642
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900